Thanksgiving NFL Parlays

Frank AmmiranteFantasy Sports & Betting Writer
Posted: Nov 22, 2022Last updated: Nov 22, 2022

Thanksgiving is finally here! It’s time to enjoy a feast with your family with a three-game slate of NFL action. It’s also the perfect day to build some parlays.

We had a much needed bounce-back, winning our best parlay in Week 11 after both the Chicago Bears/Atlanta Falcons and Cleveland Browns/Buffalo Bills games went Over.

Let’s stay hot with a Thanksgiving Day special. You’ll find a Best Bet, Longshot, and Same Game Parlay.

Here’s to a strong showing with our Week 11 Thanksgiving NFL parlays below.

Frank’s 2022 Parlay Betting Record: 9-24 (-5.84 Units)

NFL Week 12 odds used in these parlays are current as of Monday, Nov. 21, at Caesars Sportsbook.

Best NFL Week 12 Parlay

Week 12 Top Parlay (+261)

WAGER: 3 Units

  • Bills Moneyline (-420) at Lions
  • Cowboys Moneyline (-420) vs Giants
  • Vikings Moneyline (-160) vs Patriots

We’re riding with the three favorites on the moneyline as our Best Parlay for Thanksgiving. Each of these teams are in great spots for a win. The Bills and Cowboys are heavy favorites, while the Vikings are poised for a bounce-back after an embarrassing home blowout loss to Dallas.

According to Football Outsiders, Buffalo ranks seventh in Pass DVOA and third in Rush DVOA on defense. It’s hard to see how Jared Goff is going to be able to move the ball against this defense.

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Looking at the Cowboys, this is a team that is firing on all cylinders right now. They just knocked off the Vikings 40-3, which was their third win in their last four. They take on an undermanned Giants offense that just lost Wan’Dale Robinson for the season.

Minnesota got dismantled on their home field last week and now gets a short week to put that in the rearview with a win over New England. Patriots quarterback Mac Jones has been completely underwhelming this season, so we’ll take the Vikings to complete our best NFL betting pick.

Longshot NFL Week 12 Parlay

Week 12 Longshot Parlay (+386)

WAGER: 1 Unit

  • Bills at Lions Under 54 Total Points (-110) 
  • Giants at Cowboys Over 44.5 Total Points (-110)

The biggest reason why I’m rolling with the Under in the Bills/Lions game is because Josh Allen has not been himself in the last two games. He’s coming off an underwhelming game against the Browns, where he threw for 197 yards. The star quarterback is playing hurt and we’re seeing it reflected in the score line.

I’ll add the Over in the Giants/Cowboys because of how hot the Dallas offense has been lately — they’ve scored 117 points in their last three games. Dak Prescott is playing highly efficient football, while Tony Pollard has been an absolute star at running back.

NFL Week 12 Same Game Parlay

Patriots at Vikings Same Game Parlay (+282) at FanDuel

WAGER: 2 Units

  • Vikings -3 (+100) 
  • Over 42.5 Total Points (-110)

I’m confident enough in the Vikings to add them on the spread in this Same Game Parlay. This is an 8-2 team that just lost by 37 points at home. They’ll now take on Mac Jones, who has averaged 198 passing yards while throwing four touchdowns and seven interceptions this season.

We’re getting a low bar with the 42.5-point total here, so the Over looks like the safer play. Minnesota is filled with stars on offense, like Justin Jefferson and Dalvin Cook.

We could also see the Patriots have some success on the ground with Rhamondre Stevenson and Damien Harris. Just look what Tony Pollard just did to this defense.

Look for Minnesota to win by a touchdown or more, with both teams doing just enough to eclipse this total.


Frank Ammirante

Before joining The Game Day, Frank spent three years in the fantasy sports and betting industry, writing for websites like RotoBaller and 4for4football. Frank is an active member of the fantasy baseball and fantasy football community, participating in high-stakes leagues like NFBC/NFFC as well as industry competitions like Scott Fish Bowl, RazzBowl, and TGFBI. Frank is a member of the FSWA and IBWAA. Give him a shout to talk fantasy sports and sports betting.

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