NFL Schedule 2022 | Top 10 NFL Games To Watch This Season

Posted: Jun 7, 2022Last updated: Aug 25, 2022

The NFL has released its schedule for the 2022 season and there is a litany of exciting games on tap for us this year.

But which games are we the most excited to watch this season? And which games will be must-see TV?

Here are the top 10 NFL games we can’t wait to watch.

Please note that all 2022 NFL odds are courtesy of Caesars Sportsbook and are current as of Friday, May 13 at 11 a.m. ET.

Top 10 NFL Games To Watch This Season

1. Buffalo Bills @ Kansas City Chiefs

Week 6: Sunday, October 16 (4:25 p.m. ET, CBS)

One of the best games in NFL history took place last year in the AFC Divisional Round as the Chiefs completed a crazy comeback win over the Bills. Buffalo will have a chance to get revenge here as they will take on the Chiefs yet again in Kansas City.

I can’t wait to watch Patrick Mahomes vs Josh Allen once again. Sign me up. This game could very well be a preview of the AFC Championship Game for the 2022 season.

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2. Kansas City Chiefs @ Tampa Bay Buccaneers

Week 4: Sunday, October 2 (8:20 p.m. ET, SNF)

It’s Tom Brady vs Patrick Mahomes on Sunday Night Football. Need I say more?

These two teams last met in Super Bowl 55, with the Buccaneers winning that game convincingly. But this will actually be the third time the Brady-led Buccaneers will face Mahomes after playing twice in 2020.

Both teams believe they are Super Bowl contenders and this will be a huge matchup early in the season to see where each team stands after the first month of the campaign.

3. Buffalo Bills @ Los Angeles Rams

Week 1: Thursday, September 8 (8:20 p.m. ET, NBC)

The very first game of the NFL season will feature the Super Bowl champion Los Angeles Rams and the Buffalo Bills. Both teams are the current betting favorites to represent their respective conferences in Super Bowl 57 and both have elite offenses.

We should see a ton of points scored in this Thursday Night Football matchup on opening night.

4. Green Bay Packers @ Tampa Bay Buccaneers

Week 3: Sunday, September 25 (4:25 p.m. ET, FOX)

The Buccaneers have to wait until Week 3 to play their first home game and will do so against the visiting Green Bay Packers. These two teams met in the NFC Championship Game during the 2020 season, with the Buccaneers advancing to and ultimately winning the Super Bowl.

Is this the last time ever we get to see Aaron Rodgers take on Tom Brady? Maybe. So try to enjoy it.

5. Dallas Cowboys @ Green Bay Packers

Week 10: Sunday, November 13 (4:25 p.m. ET, FOX)

The Cowboys and the Packers have played some incredible games over the last few years, but this will be the first time Aaron Rodgers will get to take on his former coach Mike McCarthy.

Both Dallas and Green Bay are expected to be playoff teams again in 2022, so this big-time matchup during FOX’s late window will be must-see TV.

Don’t be surprised if this game gets some of the highest ratings we’ve ever seen for a regular-season game.

6. Kansas City Chiefs @ Cincinnati Bengals

Week 13: Sunday, December 4 (4:25 p.m. ET, CBS)

A rematch of last season’s AFC Championship Game, Patrick Mahomes and the Chiefs will travel to Cincinnati to take on Joe Burrow and the Bengals. Cincinnati won both meetings against Kansas City last year, with each game coming down to the final play.

These two teams both have elite young quarterbacks with highly explosive offenses. Don’t be surprised if this is one of the highest-scoring games of the regular season.

7. Los Angeles Chargers @ Kansas City Chiefs

Week 2: Thursday, September 15 (8:15 p.m. ET, Amazon Prime Video)

One of the best games of the season will take place in Week 2 on Thursday Night Football. The Chargers and Chiefs played two incredible games against one another last year, but it was the Chargers who made some big-time acquisitions this offseason.

Will Khalil Mack and J.C. Jackson be enough to take down the Chiefs in Kansas City? I’m not sure, but this AFC West showdown should be a blast to watch.

8. Indianapolis Colts @ Denver Broncos

Week 6: Thursday, October 6 (8:15 p.m. ET, Amazon Prime Video)

The Broncos will play a Monday Night Football game in Week 1 against the Seahawks, which will be Russell Wilson’s first time playing against his former team, but a matchup that is more intriguing comes a few weeks later.

Both the Colts and the Broncos have new starting quarterbacks, so it will be fascinating to see which one looks better at this point in the season. Indianapolis and Denver are playoff contenders in 2022, so seeing them on a primetime stage after the first month of the campaign should be a lot of fun.

9. Los Angeles Rams @ Green Bay Packers

Week 15: Monday, December 19 (8:15 p.m. ET, ESPN)

The Packers dominated the Rams in the regular season last year, but it was the Rams who advanced through the NFC playoffs to the Super Bowl. This late-season showdown on Monday Night Football will be a compelling watch as these are two of the best three teams in the conference.

10. New Orleans Saints @ Tampa Bay Buccaneers

Week 13: Monday, December 5 (8:15 p.m. ET, ESPN)

Since Tom Brady joined the Buccaneers and the NFC South, he’s had a ton of trouble getting past the Saints. Tampa Bay lost just four games last year, but two of those defeats came against New Orleans.

In fact, Tampa Bay was shut out in their second loss to the Saints last year. That’s how well New Orleans has played their division rival over the previous two years.

Another primetime matchup between these two teams will be intriguing. And the fact that this one takes place later in the season means we could have some major playoff implications on the line here in Week 13.


Marcus Mosher

Marcus Mosher is an NFL analyst at The Game Day, residing in Erie, PA. He covers the NFL from a betting and fantasy perspective, producing written and video content. Marcus currently hosts multiple football-related podcasts and is a managing editor at USA Today’s Sports Media Group covering the Las Vegas Raiders. He has previously worked at The Athletic and Bleacher Report.

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