Ghana vs Uruguay World Cup Predictions

Last Updated: Dec 2, 2022

The final matchday of Group H play will see Ghana take on Uruguay at the Al Janoub Stadium, with kickoff scheduled for 10 a.m. ET on Friday, Dec. 2.

While it’s hard to know what situation both these teams will find themselves in heading into this contest, I can guarantee a lot of the pre-match chatter will be about the unforgettable 2010 World Cup quarterfinal contested by these two nations.

Diego Forlán’s stunning second-half free-kick canceled out Sulley Muntari’s long-range opener, and it seemed as though the teams were heading for penalties until Uruguay striker Luis Suárez batted a last-gasp, goal-bound header away from the Uruguay goal with his hand.

Suárez was shown a red card and Ghana was awarded a penalty, which Asamoah Gyan struck off the crossbar, sending the match to a penalty shootout that Uruguay ultimately won. Although Uruguay would crash out in the semifinals, the play was quickly dubbed “The Second Hand of God."

With Suárez set to appear in his fourth, and likely final, World Cup for Uruguay, you can be sure that Ghana will be looking to avenge that defeat against the man who single-handedly prevented the Black Stars from becoming the first African nation to reach the World Cup semifinals.

Now that we’ve enjoyed our trip down memory lane, let’s look into this upcoming Ghana vs Uruguay matchup.

Ghana vs Uruguay Odds

  • 3-Way Handicap: Ghana (+360) | Draw (+250) | Uruguay (-145)
  • Draw No Bet: Ghana (+260) | Uruguay (-350)
  • Over/Under Goals: Over 2.5 (-108) | Under 2.5 (-126)

Ghana vs Uruguay World Cup odds are courtesy of BetMGM and are current as of 3:30 p.m. ET on Friday, Nov. 11.

Oddsmakers are once again expecting Uruguay to break Ghanaian hearts at the World Cup, which isn’t much of a surprise given the South American side sits nearly 50 places above its opposition in the latest FIFA rankings.

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Ghana vs Uruguay Prediction

Ghana 1-1 Uruguay

These two nations played to a 1-1 draw after 90 minutes 12 years ago, and it wouldn’t totally surprise me to see it happen again.

Uruguay isn’t the most adventurous side going forward and, depending on the situation, may not need more than a point from their final group game. (Read more about this quartet’s chances to advance in our World Cup Group H odds report.)

Meanwhile, Ghana could once again surprise some people, especially if Tariq Lamptey and Athletic Bilbao forward Iñaki Williams are called up after changing international allegiances. These two top-level players would be a massive boost to the squad, especially when you play them alongside Arsenal’s Thomas Partey and Ajax’s Mohammed Kudus.

Ghana vs Uruguay Betting Tips

While motivation isn’t enough of a reason to wager on a team, it will eventually tell us a little more when it comes to the potential for squad rotation (or the lack thereof) in this match.

Based on what we know now, this contest should be a physical battle between two teams that may not particularly be too fond of one another.

Even if Ghana are already eliminated before kickoff, which I’m not sure will be the case, you can expect their best effort here in a chance to play spoiler.

Ghana vs Uruguay Best Bets

Under 2.5 Total Goals (-126) at FanDuel Sportsbook

WAGER: 1 Unit

This should be a hard-fought game from the first whistle to the last. While Uruguay has the talent up front to make it a difficult day for Ghana’s defense, Diego Alonso‘s squad is known for playing things a bit more conservatively.

While I predicted a 1-1 draw, there is certainly a scenario where Uruguay keeps a clean sheet in a low-scoring win.


John Arlia

Before joining The Game Day, John served as the National Writer for the United Soccer League, where he primarily covered the USL Championship out of the league’s headquarters in Tampa, FL. A devout soccer fan, John attended the men’s World Cups in Brazil and Russia and can’t wait for the 2026 edition to come to North America. Having also written for Sporting News Canada since getting his master’s from the Walter Cronkite School of Journalism at ASU, John has acquired a diverse sporting background, but considers football, golf, and soccer his three strong suits.

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