Cardinals vs Seahawks Predictions Week 11 | NFL Pick of the Day

Week 11 features two NFC West foes battling to get back in the win column this weekend. The Arizona Cardinals (8-2) head to Seattle to take on the Seahawks (3-6).

The Cardinals are coming off their second loss of the season, a blowout 34-10 loss at home to the Carolina Panthers. The Seahawks return home in Week 11 after putting up a goose egg at Lambeau, ruining Russell Wilson‘s return from finger surgery with the team’s first shutout loss in ten years.

With that in mind, let’s take a look at our Cardinals vs Seahawks predictions and best bets.

Please note that all odds and lines are current as of 12:00 p.m. ET on Friday, November 19.

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Cardinals vs Seahawks Prediction

The Seattle defense is the ninth-best scoring defense, allowing only 20.7 points per game. It ranks second in the league over the last three weeks, however, giving up only 12.3 per game.

The Seahawks offense, led by superstar quarterback Russell Wilson and their dynamic duo of receivers DK Metcalf and Tyler Lockett, have fallen off and are now 20th in scoring.

Wilson was injured in Week 5 on Thursday Night Football against the Rams and finally came back in Week 11, only to be dominated by the Green Bay Packers defense. Seattle hasn’t had the best offensive line and hardly any running game to speak of.

Seattle just has one win this season at home. On the flip side, the Cardinals are 5-0 on the road.

Arizona’s defense is fifth in the league in scoring, but it has really started to show some weaknesses due to injuries, giving up 25 points per game over the last three games.

On the offensive side of the ball, the Cardinals are fourth in the league in points per game. What’s more remarkable is their 34.8 road points per game, good for best in the NFL.

While the Cardinals offense was buried last week against the Panthers, the Seahawks don’t have anywhere near as aggressive a defense as Carolina. There is a chance Kyler Murray returns for Arizona this week, but even if he isn’t, Colt McCoy will likely be ready. Ironically, he took the New York Giants into Seattle last year and won.

This is going to be a shocker for some, but Seattle with Russell Wilson has been a cockroach. They simply do not die and they always go through spurts where they fall off and have to come back from it.

With the Seahawks sitting at 3-7 and staring their first non-postseason finish since 2017 in the face, I expect them to play much tougher than they did against the Packers last Sunday.

Kyler Murray, whether he plays or not, may not be fully healthy. I think Seattle is going to escape with a win at home, bouncing back in a massive way after getting embarrassed a week ago.

Prediction: Seahawks 24, Cardinals 20

James Conner Arizona Cardinals RB

Can the Arizona Cardinals bounce back in their NFC West clash against the Seattle Seahawks in NFL Week 11? (Image: USA TODAY Sports)

Cardinals vs Seahawks Best Bets

Best Bet: Seahawks Moneyline (+110) at Caesars

Wager: 2 Units

After looking at our NFL gameday odds, this is a game where the Seahawks aren’t a massive underdog because of the recent injuries the Cardinals are battling. I like Seattle’s line here, but I like winning more with the moneyline odds. Since I picked Seattle to win outright, so to me this is the best bet.

I expect the Seahawks to be able to put the same amount of pressure on Murray (or McCoy) that they put on Rodgers last week. I think they will be able to find some success running the football as well. Also, coming off one of the worst losses of his career, I expect Wilson to get it together in front of the 12’s and win, pushing Seattle’s playoff odds a bit higher.

Both of these teams have talent and while the Cardinals have been the better team this year, it looks like something has clicked with the Seattle defense. If they can build off of the Packers game, they will be playing some more winning football. I think that’s exactly what happens and the Seattle offense comes alive. I’m making this my NFL bet of the day.



Seattle Seahawks Moneyline (ARI @ SEA, NFL Week 11)

ARI @ SEA | 11/21, 4:25 PM ET

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Bet $20, Payout $42

Best Bet: Under 48 (-110) at Caesars

Wager: 1 Unit

Cardinals games have combined for an average of 47.6 points this season, while Seahawks games have averaged 40.7 points.

Both teams have great red zone offenses, with Seattle scoring touchdowns in the red zone 71.43% of the time, just ahead of Arizona’s 70% clip. However, the Seahawks have the upper hand when it comes to their defense.

Seattle’s defense ranks fifth, allowing touchdowns in the red zone at a 47.22% clip. The Cardinals are 17th in the NFL in red zone defense, allowing touchdowns in the red zone 60% of the time.

This bet isn’t impossible to lose, but with the way the Seahawks are playing, I believe my 24-20 prediction is going to be right on course. If that score holds and you picked the Under, you’ll win the bet.



Under 48 Total Points Scored (ARI @ SEA, NFL Week 11)

ARI @ SEA | 11/21, 4:25 PM ET

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Bet $20, Payout $38

Thank you for reading our NFL Week 11 Cardinals vs Seahawks Predictions! For more NFL betting tips, check out our NFL Week 11 Best Bets.

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