Colorado Odds & Best Bets

Last Updated: Sep 14, 2023

Coach Prime is the biggest story in college football through September.

The University of Colorado football team is back, surpassing its 2022 win total in just two weeks. First-year coach and famed self-promoter Deion Sanders has brought the Buffaloes back from irrelevance to become the hottest team in FBS.

If you missed the chance to take the Over on Colorado’s win total, there’s still ample opportunity to cash in. Let’s take a look at how to bet on the 2023 Buffaloes.

Colorado Betting Odds

Colorado Game Odds

Colorado Current Lines

Colorado odds used in this report are current as of Sept. 14, 2023 at 11 a.m. ET, at the sportsbooks cited.

Colorado: Win National Championship (+8000)

DraftKings Sportsbook

Colorado may have stunned national runner-up TCU in its initial game, then rolled longtime rival Nebraska, but the Buffaloes are still a national-championship longshot. Colorado has a hellacious schedule that is about to be realized, as though facing off on the road against the Horned Frogs wasn’t difficult enough.

But Sanders and the Buffaloes will square off against the best of the Pac-12, starting with their road game at Oregon on Sept. 23. They will then host reigning Heisman Trophy winner Caleb Williams and Pac-12 favorite USC before late-season road matchups at UCLA, Washington State, and reigning conference champ Utah.

If Colorado can survive all that, it’ll probably have to beat Utah, USC, or Oregon in the Pac-12 championship game, then win both College Football Playoff games. You can see why the odds are this long.

Find more updated CFB National Championship odds and bets at The Game Day.

Colorado: Win Pac-12 (+1800)

DraftKings Sportsbook

This seems slightly more practical, though again the schedule is prohibitive, as may be the Buffaloes defense.

Still, Vegas isn’t a believer yet in Colorado’s ability to win the conference, since it still has the sixth-shortest odds. If you feel Sanders and Co. can go from worst to first, the odds are worth a sprinkle.

Colorado Best Prop Bets

Colorado: Over 6.5 Regular-Season Wins (-170)

DraftKings Sportsbook • WAGER: 1 Unit

The Buffaloes have a hellacious schedule where six of their final 10 regular-season games will be against ranked opponents, and four of those games will be on the road. But Colorado already defeated a ranked team away from home (TCU) and is about one-third of the way to seven wins.

Colorado isn’t likely to run the table, even though it is the feel-good story of the season so far. But bowl eligible? That seems like a lock, which makes this bet worth placing, despite the substandard odds.

Shedeur Sanders: Heisman Trophy (+1800)

DraftKings Sportsbook • WAGER: 0.25 Units

Shedeur Sanders is the Colorado quarterback and son of Deion, and he has electrified the college-football world by surpassing 900 passing yards and posting a 6-0 TD/INT ratio through two games. The Jackson State transfer has catapulted both the Buffaloes offense and his own Heisman Trophy candidacy by lighting up TCU and Nebraska.

Williams, the USC QB, is still the frontrunner to become only the second player ever to win the Heisman multiple times. But Sanders will have the opportunity to square off against Williams directly and could supplant him by outplaying him and if Colorado can defeat USC.

Plus, if he does have a huge game against the Trojans and Colorado doesn’t win, there’s still a chance Sanders could get into the Heisman conversation. Voters are apt to find a candidate who could supplant Williams since no player has repeated as Heisman since Archie Griffin in 1973 and 1974.

Sanders could certainly be that guy, especially with his father playing the role as promoter all season.

Get the latest Heisman Trophy odds and bets from TGD’s Lance Patton.

Find the best Colorado betting sites

Place your college football bets in Colorado:


Pat Pickens

Pat Pickens is a seasoned sportswriter who has covered pro sports since 2013 for various websites, including The New York Times,, Bleacher Report,, USA Today, the Associated Press and many others. His debut book, titled "The Whalers" about the history of the NHL's Hartford Whalers, was released in October 2021.

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