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SNF Predictions Week 7 | Falcons vs 49ers

Last Updated: Oct 15, 2025

The Week 7 edition of Sunday Night Football will see the Atlanta Falcons (3-2) visit the San Francisco 49ers (4-2) in an NFC clash.

Atlanta is coming off its biggest win of the season, defeating the Buffalo Bills 24-14 on Monday night. Meanwhile, San Francisco suffered a 30- 19 setback at the Tampa Bay Buccaneers on Sunday.

Below, I will dive into my Falcons vs 49ers best bets and predictions for this Sunday Night Football matchup.

Updated SNF Odds Comparison

The 49ers enter this matchup as 2.5-point favorites despite heading into this game with several injuries on both sides of the ball. The over/under for this matchup is 47.5 points, making it one of the highest totals on the Week 7 slate.

All NFL odds used for these Sunday Night Football predictions are current as of Wednesday, Oct. 15, and courtesy of DraftKings Sportsbook.

SNF Implied Scores & Team Totals

49ers 25, Falcons 22.5

Oddsmakers expect San Francisco to get back on track with a narrow Week 7 victory.

Sportsbook Play of the Day

Sunday Night Football Predictions

SNF Score Prediction: Falcons 24, 49ers 20

This is a dangerous spot to back the Falcons, as they are coming off their biggest win of the season — a statement home victory over the Buffalo Bills. However, I like Atlanta to continue its impressive run with a road victory on a short week.

The 49ers are dealing with several injury concerns on both sides of the ball. Quarterback Brock Purdy has not played in multiple weeks but could return to action on Sunday. He could be joined by wide receiver Ricky Pearsall and tight end George Kittle, who also missed Sunday’s loss to Tampa Bay.

While some offensive reinforcements could be on the way, more are needed for the defense. Standout linebacker Fred Warner suffered a season-ending ankle injury on Sunday, a massive blow to a unit that already lost All-Pro defensive lineman Nick Bosa (torn ACL) for the year.

While Kyle Shanahan’s squad has done well to maintain a 4-2 record despite numerous injuries, I expect those concerns to take their toll on Sunday against Atlanta.

Sunday Night Football Bet Tips

Keep these bet tips and trends in mind before making your Sunday Night Football bets.

  • The Falcons have won three of the last four meetings between these teams.
  • The 49ers are 2-2 against the spread as a favorite this season.
  • Atlanta’s games are 4-1 to the Under, while San Francisco’s are 4-2 to the Over.

Sunday Night Football Best Bets

SNF Over/Under Pick: Falcons @ 49ers Under 47.5 Points (-115)

Atlanta’s games have tended to go under the total this season, which makes sense since the Falcons have allowed the fewest yards per game (253.4) in the NFL.

New defensive coordinator Jeff Ulbrich has this unit playing at a high level, as we saw when Atlanta limited Josh Allen and the Bills to 14 points on Monday night.

San Francisco has some offensive pieces getting healthy, but it wouldn’t surprise me if Purdy takes some time to shake off the rust after a few weeks on the sidelines.

SNF Pick Against the Spread: Falcons +2.5 (-112) at 49ers

I like the Falcons to win this game outright as 2.5-point underdogs, but I’ll take the points just in case it’s close.

Atlanta quarterback Michael Penix Jr. has this offense humming. Last week, Atlanta accumulated more than 200 yards on the ground and through the air in their win over the Bills, with running back Bijan Robinson and wide receiver Drake London both going over 150 total yards on their own.

The 49ers struggled to stop Baker Mayfield and a host of backup weapons last week against the Buccaneers, allowing 30 points in a loss. They will not be able to match up against a more talented outfit in this one, especially considering their injuries.

I’ll take the Falcons as my best NFL bet today.

Sunday Night Football Prop Bet

SNF Prop Bet: Falcons Over 23.5 Points (+100)

While returning defensive coordinator Robert Saleh has reenergized the 49ers’ defense, the former New York Jets head coach is currently short on players.

Injuries are particularly prevalent along the defensive front and at linebacker, which is a significant concern in this matchup against the Falcons’ rushing attack led by Robinson.

Additionally, San Francisco has the second-worst pressure rate in the NFL this season (10%), meaning Penix will have plenty of time to pick apart this secondary.

Sunday Night Football Parlay

Best SNF Same-Game Parlay (+300)

  • Falcons ML
  • Under 47.5 Points

Player props aren’t available for this Sunday Night Football matchup yet, so I’m going to lean into my side and total picks for this SNF parlay.

The Falcons and the Under play well together, given Atlanta’s strength on defense, and I like the healthier, more confident team this week to pull out a low-scoring road win.

Author

John Arlia

Before joining The Game Day, John served as the National Writer for the United Soccer League, where he primarily covered the USL Championship out of the league’s headquarters in Tampa, FL. A devout soccer fan, John attended the men’s World Cups in Brazil and Russia and can’t wait for the 2026 edition to come to North America. Having also written for Sporting News Canada since getting his master’s from the Walter Cronkite School of Journalism at ASU, John has acquired a diverse sporting background, but considers football, golf, and soccer his three strong suits.

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