NFL Prop Bets Week 6

Last Updated: Oct 12, 2023

After a forgettable showing the previous week, I rebounded to respectability in Week 5. I hit on three of five game props, moving my record to 19-23 in the ongoing quest to get back to .500.

This week, I zoom in on what should be an exciting game between the Seattle Seahawks and Cincinnati Bengals, while also taking advantage of projected blowouts. An underrated defense also gets its due attention.

Week 6 NFL Prop Bets

NFL Week 6 odds used for prop bets are current as of Thursday, Oct. 12.

Dolphins vs Panthers: MIA To Win Both Halves (-120)

DraftKings Sportsbook • WAGER: 1.5 Units

This wager seems like a slam dunk as I try to take advantage of the mismatch of the week. The winless Panthers don’t have much hope to keep up with the most explosive offense since the 2013 Denver Broncos.

Miami leads the NFL in first-half points per game at 20.6, while Carolina averages 9.2. The Dolphins average the second-most second-half points per game (15.6), and the Panthers average 9.0.

Lock in Miami to get on the board early and often with our NFL bet of the day.

Bengals vs Seahawks: Both Teams to Score 20+ Points (+135)

DraftKings Sportsbook • WAGER: 1.5 Units

Seattle is averaging 27.8 points per game, which ranks fifth in the NFL, and the Bengals looked like the better version of themselves in Week 5 when they scored a season-high 34 points. Joe Burrow is apparently rounding into form after battling a calf issue that hindered him more significantly in previous weeks.

In Week 5, Burrow set season highs in completions (36), yards (317) and TD passes (three). Geno Smith has 19 TD passes in his last 10 road starts and will do his part to help us cash on one of my favorite NFL props for Week 6.

Bills vs Giants: BUF to Score Over 13.5 2nd Half Points (-115)

DraftKings Sportsbook • WAGER: 1.5 Units

It is not much to ask from the Bills to approach their second-half average of 14.2 points overall, which is also at 17.0 for home games and in the last three overall. It will not surprise anyone if Buffalo surpasses the projected total on two quick drives.

The home team will heavily lay the offensive totals onto an inferior opponent after coming off a stinging Week 5 loss. The Bills will pull away further in the second half while getting well past the number here, even if their reserves get some run in a laugher.

Cowboys @ Chargers: DAL 1st To Score/Moneyline (+180)

DraftKings Sportsbook • WAGER: 1 Unit

The Cowboys must put the Week 5 debacle against San Francisco behind them as rapidly as possible. They will be determined to get on the board quickly, and Dallas needs this win to re-establish that they are a legitimate playoff team.

Dak Prescott has won four of five career starts on Monday night. He will wave off his critics for at least one week with a quality performance that spurs the Cowboys to a bounce-back win on the national stage.

Commanders @ Falcons: WAS Under 20.5 Points (-122)

DraftKings Sportsbook • WAGER: 1.5 Units

A solid Atlanta defense deserves more recognition. The Falcons allow 19.2 points per game and have not let up more than 20 points in two of their past three games.

Washington has not scored over 20 points in three of its five games in 2023.

Week 6 NFL Player Props

Michael Pittman Jr.: Over 61.5 Receiving Yards (-115) @ Jaguars

DraftKings Sportsbook • WAGER: 1.5 Units

Pittman is certainly looking forward to facing the Jaguars, and we should be doing the same as prop enthusiasts. In his last two games against Jacksonville, the Colts WR has 21 receptions for 231 yards.

Former Jaguar Gardner Minshew will be at QB for the Colts this week, and he is not afraid to sling the ball. Getting the ball frequently to Pittman will be his focus, and the Jaguars rank 24th in receiving yards allowed to WRs.

Tyler Lockett: Anytime TD Scorer (+185) @ Bengals

DraftKings Sportsbook • WAGER: 1 Unit

Seahawks-Bengals will likely be one of the most fun games of the week. Expect Lockett to get involved often, as Seattle will trade offensive punches with Cincinnati.

The Seahawks veteran does some of his better work as a visitor. Lockett has five TD receptions in his last five road games.

Garrett Wilson.: Over 51.5 Receiving Yards (-115) vs Eagles

DraftKings Sportsbook • WAGER: 1 Unit

The Jets’ No. 1 WR appears on my Week 6 rundown of fantasy football sleepers, as he can outperform tepid expectations against Philadelphia. Zach Wilson has started to perform better over the past two weeks, and New York’s best playmakers can exploit the Philadelphia secondary.

The Eagles rank 27th in yards allowed to opposing WRs.

Matthew Stafford: Over 280.5 Passing Yards (-115) vs Cardinals

DraftKings Sportsbook • WAGER: 1 Unit

I whiffed on a Stafford passing prop last week against the Eagles, but I was likely just a week late on cashing in with him. The Rams’ QB is fourth in the NFL in passing yardage, and Cooper Kupp has returned to form a very good WR trio with Puka Nacua and Tutu Atwell.

Arizona ranks 29th in passing yards allowed to QBs.

James Cook: Over 76.5 Rushing + Receiving Yards (-115) vs Giants

DraftKings Sportsbook • WAGER: 1 Unit

Cook has a good matchup to showcase his dual-threat abilities this week. The Giants rank 31st in rushing yards allowed to RBs, and that number serves as a solid basis for Cook to ease past the projected total.

In three of his past four games, Cook has totaled 75-plus scrimmage yards and should have little difficulty approaching that number again in a one-sided game.

Find Top NFL Props

Check out the best player prop bets this week with our props comparison tool. Click on a game below to see all of its prop bets.


Scott Engel

Scott Engel is a Senior Sports Writer at The Game Day. Previously he was at and The Athletic. His work is also featured at RotoBaller and on Scott is a host on SiriusXM Fantasy Sports Radio. He is an inaugural member of the Fantasy Sports Writers Association's Hall of Fame. Scott is a four-time FSWA award winner and a 13-time finalist. He was an Associate Editor and featured writer at and his career began at CBS SportsLine, where he was a Senior Writer and Managing Editor. Scott was the Managing Director at RotoExperts.

Related articles


Get $1,500 in Bonus Bets

5 stars

Bet $5, Get $150 in Bonus Bets or First Bet Safety Net

5 stars

Bet $5, Get $150in Bonus Bets

5 stars

Get A Bonus Bet Up to $1,000

5 stars

Bet $5, Get $200 in Bonus Bets

5 stars

Get Up To $250 Second Chance Bonus Bet

5 stars

If you or someone you know has a gambling problem and wants help, please call 1-800-GAMBLER.

21+ and present in OH. Gambling Problem? Call or text 1-800-GAMBLER (CO, DC, IL, IN, LA, MD, MS, NJ, OH, PA, TN, VA, WV, WY).

Call 877-8-HOPENY or text HOPENY (467369) (NY).

Please Gamble Responsibly. Call 1-800-NEXT-STEP (AZ), 1-800-522-4700 (KS, NV), 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-270-7117 for confidential help (MI).

All betting content on is exclusively intended for audience members 21 years and older who are permitted to gamble in legal states. The Game Day may earn revenue from site visitor referrals to betting services.

Responsible Gaming: Many sportsbooks offer ways to encourage responsible gaming, including the establishment of limits to deposits, spending, and time dedicated to betting.

The Game Day is a TGD Marketing Ltd. endeavor.