Think you’ve got what it takes to outsmart your co-workers with your NFL ATS picks this season? Us too.
This season, The Game Day’s staff will be picking every NFL game against the spread in a season-long competition that will run through Super Bowl 59 in New Orleans. We’ll also break down our best ATS bet for each week, and see who can compile the best record over the course of the year.
Whether you’re playing in your office pick’em pool or a high-profile ATS picks contest, we’ll give you all the insight you need to stay ahead of the game all season long.
NFL odds used for these Week 3 ATS picks are courtesy of DraftKings Sportsbook and current as of Tuesday, Sept. 17, at 9:30 a.m. ET.
NFL Week 3 ATS Picks
TGD NFL Staff Writers: Frank Ammirante, John Arlia, Garrett Chorpenning, David Kaestle, Rich Migliorisi
| Week 3 | Ammirante | Arlia | Chorpenning | Kaestle | Migliorisi |
|---|---|---|---|---|---|
| NE @ NYJ (-6.5) | NYJ | NE | NE | NE | NYJ |
| NYG @ CLE (-6) | CLE | CLE | CLE | NYG | CLE |
| GB @ TEN (-3) | TEN | TEN | GB | GB | TEN |
| CHI @ IND (-2) | IND | CHI | IND | CHI | IND |
| HOU @ MIN (+2.5) | HOU | HOU | MIN | HOU | HOU |
| PHI @ NO (-1) | NO | PHI | NO | PHI | NO |
| LAC @ PIT (-2) | LAC | LAC | PIT | LAC | PIT |
| DEN @ TB (-6.5) | TB | DEN | TB | TB | DEN |
| CAR @ LV (-5) | CAR | CAR | LV | LV | LV |
| MIA @ SEA (-5) | SEA | MIA | SEA | SEA | SEA |
| BAL @ DAL (+1) | BAL | BAL | DAL | BAL | BAL |
| SF @ LAR (+7) | SF | SF | SF | LAR | SF |
| DET @ ARI (+2.5) | DET | DET | ARI | DET | DET |
| KC @ ATL (+3.5) | KC | KC | KC | KC | KC |
| JAC @ BUF (-5.5) | BUF | JAC | BUF | BUF | BUF |
| WAS @ CIN (-8) | CIN | WAS | CIN | CIN | CIN |
| Best Bet | SF -7 | SF -7 | TB -6.5 | TB -6.5 | TB -6.5 |
2024 Season ATS Picks Record (Best Bet Record)
- Ammirante 14-15-3 (0-2)
- Arlia 13-16-3 (1-0-1)
- Chorpenning 16-3-3 (1-1)
- Kaestle 13-16-3 (1-1)
- Migliorisi 14-15-3 (2-0)
Sportsbook Play of the Day
NFL Week 3 ATS Best Bets
49ers -7 (-115) @ Rams
The Rams are absolutely decimated with injuries, with a list that includes Puka Nacua, Cooper Kupp, John Johnson III, Jonah Jackson, Steve Avila, and Joe Noteboom.
While the 49ers are without Deebo Samuel and Christian McCaffrey, there’s still enough talent here to cruise to victory against a Rams team with major pass protection issues.
Not to mention, we just saw Los Angeles get completely shredded by Kyler Murray and the Cardinals. Good luck stopping Kyle Shanahan’s offense this week. – FRANK AMMIRANTE
- For more of Frank’s favorite bets, check out his NFL prop bets today.
Kyle Shanahan has dominated head-to-head meetings with Sean McVay in recent seasons, so I’m fine laying seven with the Niners on the road.
San Francisco has won nine of its last 11 games against Los Angeles, with six of those victories coming by seven or more points.
This matchup has historically been bad for the Rams, who are severely short-handed heading into Week 3. Much like last week’s contest against the Cardinals, this game could get out of hand quickly. – JOHN ARLIA
Buccaneers -6.5 (-115) vs Broncos
Tampa Bay has gotten off to an impressive start, throttling Washington at home before taking down Detroit on the road in Week 2. Baker Mayfield’s five passing touchdowns lead the NFL, and the team has yet to allow a score through the air.
The same can’t be said for Denver, which fell to 0-2 after scoring just six points against Pittsburgh over the weekend. The Broncos have one touchdown on the year, and rookie QB Bo Nix has thrown a league-high four interceptions.
Based on what we’ve seen so far, the Buccaneers should dominate this game on both sides of the ball and win by at least a touchdown. – GARRETT CHORPENNING
- For more of our favorite plays this week, check out our NFL parlay picks.
Based on preseason expectations, the Buccaneers have arguably gotten off to the most impressive start in the NFL this season through two weeks. Behind great defensive play and a no-fluke resurgence of Baker Mayfield’s career, the Bucs are humming. The offense hasn’t missed a beat without former OC Dave Canales, as Mike Evans and Chris Godwin look like the best WR duo in the league.
None of the same can be said for the Broncos offense, which is still struggling to get its footing under HC Sean Payton and rookie QB Bo Nix. The Bucs stifled one of the most talented offenses in the league last week, the Detroit Lions, on their home field.
I don’t see them struggling back in Tampa against a much less lethal offense. This defense will be Nix’s toughest NFL test to date, and I don’t expect him to find his first NFL success against them in Week 3. – DAVID KAESTLE
Not to sound like a broken record with the others here picking the Bucs as their lock of the week, but sometimes it is best to go with the most obvious pick.
No need to break this one down as the rest of The Game Day staff already has, but this spread is simply too light. – RICH MIGLIORISI
NFL Odds Against the Spread
Before making your football bets today, use our odds comparison tool to ensure you get the best ATS odds and betting lines:
