NFL Week 3 Parlays Picks & Predictions – NFL Play of the Day

Frank AmmiranteSenior Sports Writer
Last Updated: Oct 27, 2022

Thanks for navigating to The Game Day’s NFL betting coverage! Click to read our new home for NFL Week 3 parlays.

It was another poor week of parlay betting here, as we weren’t able to hit any of our bets. The Steelers’ surprising home loss against the Raiders was the death blow.

You need to remember to show patience if you’re focusing on parlay betting since they’re difficult to win, but when you finally do hit, it’s a nice payout!

This week, we’ve got more data on teams, which will help us hit some parlays. Let’s take a look at the best parlay bets for Week 3 in the NFL play of the day series!

Please note that all odds are current as of Wednesday, September 22.

Best NFL Parlays Week 3

NFL Week 3 Parlay Picks

  • Washington Football Team +8 (-110) Spread at BetMGM (at Buffalo Bills)
  • Chicago Bears +7 (-110) Spread at BetMGM (at Cleveland Browns)
  • Pittsburgh Steelers -3 (-110) Spread at BetMGM (vs Cincinnati Bengals)

Sportsbook Play Of The Day

Before continuing on to our Week 3 parlay betting tips, you should know that WynnBET is one of the best sportsbooks around, offering tons of promotions and a fantastic $1,000 bonus bets welcome bonus to !

Read Juan Carlos Blanco’s WynnBET review for more insight and get your welcome bonus below, or continue on to our Week 3 parlay tipster picks.

Washington Football Team +8 (-110) Spread

The Washington Football Team come in as 8-point underdogs, which seems to be too high for a team that got 10 days of rest following a Thursday night victory over the New York Giants. While Washington ranks No. 16 in pass DVOA and No. 21 in run DVOA, this defense is too talented to keep playing like this.

The Buffalo Bills are coming off an impressive blowout win against the Miami Dolphins, but their offense looks out of sorts right now. Josh Allen is only completing 56% of his passes with 5.3 yards per attempt through two games. This spread feels too high for Buffalo.

Chicago Bears +7 (-110) Spread

The Chicago Bears held on to beat the Cincinnati Bengals last week, and it looks like dynamic rookie quarterback Justin Fields will make his first career start with Andy Dalton on the shelf. Fields is a dual-threat playmaker who can add another dimension to this offense, which is reflected in the NFL gameday odds.

The Cleveland Browns took care of business at home against the Houston Texans, but they lost wideout Jarvis Landry to injury. If Odell Beckham Jr. can’t go for another week, that leaves them with Donovan Peoples-Jones and Anthony Schwartz as their starting wideouts.

Pittsburgh Steelers -3 (-110) Spread

The Pittsburgh Steelers came into Week 2 riding high after an upset win over the Bills, but they had a letdown game against the Las Vegas Raiders. Look for them to have a better performance against the Cincinnati Bengals.

Bengals quarterback Joe Burrow crashed back to Earth against the Bears following a great performance against the Minnesota Vikings, completing only 6.9 yards per attempt with 3 interceptions. It’s going to be tough for him against a Steelers defense that shut down Josh Allen, which makes this one of our picks of the day.

Najee Harris, RB, Pittsburgh Steelers

After a disappointing loss to the Las Vegas Raiders, rookie RB Najee Harris could play a big role in Pittsburgh’s next outing with the Cincinnati Bengals.

NFL Week 3 Longshot Parlay Prediction

  • Washington Football Team +8 (-110) Spread at BetMGM (at Buffalo Bills)
  • Chicago Bears +7 (-110) Spread at BetMGM (at Cleveland Browns)
  • Pittsburgh Steelers (-165) Moneyline at BetMGM (vs. Cincinnati Bengals)
  • New York Giants (-160) Moneyline at BetMGM (vs. Atlanta Falcons)
  • New Orleans Saints +2.5 (-110) Spread at BetMGM (at New England Patriots)

This week’s longshot parlay will start with Washington and Chicago, as I believe both spreads are too high considering the Bills’ offensive struggles and Browns’ injuries. I suggest also making a smaller parlay with these two teams on the moneyline, because both are live dogs here.

I’ll add the Steelers moneyline as insurance in case they don’t cover the 3-point spread, which is a definite possibility considering both Bengals’ games have been decided within 3 points. I’d be surprised if the Steelers lose this game, though.

The Giants moneyline looks like a good bet, as quarterback Daniel Jones is playing very well right now and running back Saquon Barkley looks poised for a strong outing against a struggling Atlanta Falcons’ defense.

The Saints should be able to cover the 2.5-point spread because of their proficiency at shutting down opposing running games. This makes them a bad matchup for the Patriots, who like to establish the run with Damien Harris.

Same Game Parlay Picks Week 3

  • Jacksonville Jaguars +7.5 (-115) Spread at BetMGM (vs Arizona Cardinals)
  • Cardinals/Jaguars OVER 52 (-110) Total at BetMGM

The Jacksonville Jaguars have lost both games to start off the Urban Meyer era; one by 16 points and the other by 10. Rookie quarterback Trevor Lawrence is struggling mightily, throwing several uncatchable balls to his talented group of wideouts.

The Arizona Cardinals, on the other hand, are riding high with a 2-0 start, taking care of business with a blowout win over the Tennessee Titans and nail-biter against the Minnesota Vikings. The Cardinals look like a clear-cut public play in this spot.

You have two teams headed in opposite directions. This game profiles as a trap for the Cardinals, who have a massive road game against the division rival Los Angeles Rams in Week 4. There’s a chance that they take the Jags lightly, resulting in a closer game than expected.

The Over looks appealing even with Jacksonville’s struggles on offense. The Jags rank No. 2 in pace of play in neutral game scripts (score within 7 points), while the Cardinals have scored 72 points in two games this season. This has the look of a shootout, which makes it our NFL bet of the day.

Thanks for reading our NFL Week 3 Best Parlay Bets and Predictions! For more NFL betting tips, check out our NFL Week 3 Best Bets and Predictions.


Frank Ammirante

Frank Ammirante is a Senior Sports Writer at The Game Day. Previously, he wrote for 4for4 Football and RotoBaller. Frank is a member of the Fantasy Sports Writer's Association while maintaining an active presence within the community. He has competed in industry contests like the Scott Fish Bowl, The Great Fantasy Baseball Invitational, and more. Frank will be making his debut in Tout Wars this year. He's got a diverse sporting background, but specializes in football and baseball.

Related articles


Get $1,500 in Bonus Bets

5 stars

Bet $5, Get $150 in Bonus Bets or First Bet Safety Net

5 stars

Bet $10, Get $200 in Bonus Bets

5 stars

Get A Bonus Bet Up to $1,000

5 stars

Bet $5, Get $200 in Bonus Bets

5 stars

Get A Bonus Bet Up To $250

5 stars

Bet $5, Get $200 in Bonus Bets Every Day for 5 days!

5 stars

If you or someone you know has a gambling problem and wants help, please call 1-800-GAMBLER.

21+ and present in OH. Gambling Problem? Call or text 1-800-GAMBLER (CO, DC, IL, IN, LA, MD, MS, NJ, OH, PA, TN, VA, WV, WY).

Call 877-8-HOPENY or text HOPENY (467369) (NY).

Please Gamble Responsibly. Call 1-800-NEXT-STEP (AZ), 1-800-522-4700 (KS, NV), 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-270-7117 for confidential help (MI).

All betting content on is exclusively intended for audience members 21 years and older who are permitted to gamble in legal states. The Game Day may earn revenue from site visitor referrals to betting services.

Responsible Gaming: Many sportsbooks offer ways to encourage responsible gaming, including the establishment of limits to deposits, spending, and time dedicated to betting.

The Game Day is a TGD Marketing Ltd. endeavor.