2021 March Madness Guide: NCAA Tournament Bracket Predictions, Bet Picks, & DFS Plays

Read our full 2021 March Madness Guide, complete with NCAA Tournament bracket picks, upset specials, sleeper teams and predictions.

2021 March Madness Guide: Bracket Picks, Upsets, Sleepers, & Predictions

2021 March Madness Schedule

(Per NCAA.com. All times ET.)

• First Four: Thursday, March 18 — 4 p.m. first tip-off
• First Round: Friday, March 19, & Saturday, March 20 — 12 p.m. first tip-off
• Second Round: Sunday, March 21, & Monday, March 22 — 12 p.m. first tip-off
• Sweet 16: Saturday, March 27 — 2 p.m. ET first tip-off; & Sunday, March 28 — 1 p.m. first tip-off
• Elite Eight: Monday, March 29 — 7 p.m. first tip-off; & Tuesday, March 30 — 6 p.m. first tip-off
• Final Four: Saturday, April 3 — 5 p.m. first tip-off
• NCAA Championship Game: Monday, April 5 — 9 p.m. tip-off

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2021 March Madness Game DFS Tips

• 2021 Final Four DFS Game Picks on Monkey Knife Fight

2021 March Madness Game Bet Tips

FINAL 4

• 1 Baylor vs. 2 Houston Bet Tips & Predictions (5:14 p.m. ET)
• 1 Gonzaga vs. 11 UCLA Bet Tips & Predictions (8:34 p.m. ET)

ELITE 8

MONDAY, MARCH 29

• Midwest Region Final: 2 Houston vs. 12 Oregon State Bet Tips (7:15 p.m. ET)
• South Region Final: 1 Baylor vs. 3 Arkansas Bet Tips (9:57 p.m. ET)

TUESDAY, MARCH 30

• West Region Final: 1 Gonzaga vs. 6 USC Bet Tips (7:15 p.m. ET)
• East Region Final: 1 Michigan vs. 11 UCLA Bet Tips (9:57 p.m. ET)

SWEET 16

SATURDAY, MARCH 27

• Midwest Region: 12 Oregon State vs. 8 Loyola Chicago Pick & Bet Tips
• South Region: 1 Baylor vs. 5 Villanova Pick & Bet Tips
• South Region: 3 Arkansas vs. 15 Oral Roberts Pick & Bet Tips
• Midwest Region: 2 Houston vs. 11 Syracuse Pick & Bet Tips

SUNDAY, MARCH 28

• West Region: 1 Gonzaga vs. 5 Creighton Pick & Bet Tips
• East Region: 1 Michigan vs. 4 Florida State Pick & Bet Tips
• East Region: 2 Alabama vs. 11 UCLA Pick & Bet Tips
• West Region: 6 USC vs. 7 Oregon Pick & Bet Tips

2021 March Madness Features

• 3 Breakout Players From 2021 NCAA Tournament
• Reliving Cinderella & Upsets from First Weekend of 2021 NCAA Tournament

2021 March Madness Bracket Preview & Futures Bet Tips

• 2021 March Madness West Region Preview & Predictions
• 2021 March Madness South Region Preview & Predictions
• 2021 March Madness East Region Preview & Predictions
• 2021 March Madness Midwest Region Preview & Predictions

2021 March Madness Picks & Predictions

• Top 5 Cinderella Sleepers For 2021 March Madness Brackets
• 3 March Madness First-Round Upsets For The 2021 NCAA Tournament

2021 March Madness Betting Odds

Odds To Win 2021 NCAA Tournament

From BetMGM, current as of Sunday, March 14, at 11 p.m. ET:

• Gonzaga (+250)
• Baylor (+300)
• Michigan (+600)
• Illinois (+600)
• Oklahoma State (+1600)
• Iowa (+1600)
• Ohio State (+1600)
• Alabama (+1600)
• Florida State (+2000)
• Houston (+2000)
• West Virginia (+2000)
• Texas (+2000)
• Kansas (+2500)
• Creighton (+2500)
• Texas Tech (+2500)
• Virginia (+3500)
• Oklahoma (+3500)
• USC (+3500)
• Arkansas (+3500)
• Villanova (+4000)
• Tennessee (+4000)
• Purdue (+4000)
• UConn (+4000)
• Loyola Chicago (+4000)
• Wisconsin (+4000)
• San Diego State (+5000)
• Oregon (+5000)
• North Carolina (+5000)
• LSU (+5000)
• Michigan State (+6600)
• Virginia Tech (+6600)
• Missouri (+6600)
• Colorado (+6600)
• Utah State (+6600)

See BetMGM’s odds for the rest of the 2021 NCAA Tournament championship field.

2021 March Madness Bracket

West Region

• (1) Gonzaga (No. 1 overall seed) vs. (16) Norfolk State/Appalachian State
• (8) Oklahoma vs. (9) Missouri
• (5) Creighton vs. (12) UC Santa Barbara
• (4) Virginia vs. (13) Ohio
• (6) USC vs. (11) Wichita State/Drake
• (3) Kansas vs. (14) Eastern Washinton
• (7) Oregon vs. (10) VCU
• (2) Iowa vs. (15) Grand Canyon

South Region

• (1) Baylor vs. (16) Hartford
• (8) North Carolina vs. (9) Wisconsin
• (5) Villanova vs. (12) Winthrop
• (4) Purdue vs. (13) North Texas
• (6) Texas Tech vs. (11) Utah State
• (3) Arkansas vs. (14) Colgate
• (7) Florida vs. (10) Virginia Tech
• (2) Ohio State vs. (15) Oral Roberts

Midwest Region

• (1) Illinois vs. (16) Drexel
• (8) Loyola Chicago vs. (9) Georgia Tech
• (5) Tennessee vs. (12) Oregon State
• (4) Oklahoma State vs. (13) Liberty
• (6) San Diego State vs. (11) Syracuse
• (3) West Virginia vs. (14) Morehead State
• (7) Clemson vs. (10) Rutgers
• (2) Houston vs. (15) Cleveland State

East Region

• (1) Michigan vs. (16) Mount St. Mary’s/Texas Southern
• (8) LSU vs. (9) St. Bonaventure
• (5) Colorado vs. (12) Georgetown
• (4) Florida State vs. (13) UNC Greensboro
• (6) BYU vs. (11) Michigan State/UCLA
• (3) Texas vs. (14) Abilene Christian
• (7) UConn v. (10) Maryland
• (2) Alabama vs. (15) Iona