Giants vs Diamondbacks Predictions & Best Bets | Picking Against the Spread

Last Updated: Aug 17, 2022

The Diamondbacks (53-62) will once again visit the Giants (58-57) in Game 2 of this regular season double header on Wednesday, August 17 at Oracle Park in San Francisco. Each team will be eager to come out on top as they work their way through the final stretch of the regular season. Catch all the action at 6:45 p.m. PT!

For their upcoming game, the Giants have earned a win against their opponents. In their most recent meeting on Tuesday, the score was 2-1 in favor of the Giants. The Giants had six runs to the Diamondbacks one run. Be sure to tune in and see how it all plays out at Oracle Park.

Giants vs Diamondbacks Prediction

The oddmakers believe that the Giants have better chances of taking this one. Per FanDuel, they are at -220 odds for victory, while Arizona are +184. Total runs for this contest is predicted to be 7.

The last time these two teams met, the Giants defeated the Diamondbacks on Monday, by a 6-1 margin. Led by their top hitter, Thairo Estrada, who has a batting average of .269, the team is currently batting .237 so far this season. In terms of defense, the team has put up an ERA of 3.9 and a .984 fielding percentage.

In their last showdown on Monday, the Diamondbacks lost to the Giants by a score of 6-1. So far this season, the team is currently batting .194, thanks in large part to their top hitter, Joshua Rojas, who has a batting average of .275. Defensively, they have an ERA of 4.17 and a .984 fielding percentage. Be sure to take a look at our odds analysis and make your choices based on the teams’ recent performances!

The latest squad news is that the Giants are missing José Álvarez (Elbow), Mauricio Llovera (Hip), Colton Welker (Shoulder), Evan Longoria (Hamstring), Samuel Delaplane (Forearm), Zack Littell (Oblique) and Anthony DeSclafani (Ankle). And the Diamondbacks are without Keynan Middleton (Ankle), Caleb Smith (Hand), Tyler Gilbert (Elbow), Kyle Nelson (Back), Humberto Castellanos (Elbow), Ketel Marte (Hamstring) and Nicholas Ahmed (Shoulder).

Moneyline Pick: Giants (-220) at FanDuel

The team is considered the favorite according to the betting market. In their previous confrontation against these opponents, the Giants won 2-1.

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Giants vs Diamondbacks Betting Odds

  • Moneyline: San Francisco (-220), Arizona (+184) at FanDuel
  • Run Line: San Francisco -1.5 (+106), Arizona 1.5 (-128) at FanDuel
  • Over/Under: Under 7 Runs (102), Over 7 Runs (-124) at FanDuel

View all the top MLB betting odds with our awesome lines comparison feature.

Giants vs Diamondbacks Betting Trends

  • Win % as favorite: Giants 0.74%, Diamondbacks 0.3%
  • Win % as underdog: Giants 0.14%, Diamondbacks 0.5%
  • Win-loss record last 10 games: San Francisco 7-3, Arizona 6-4

Runline Pick: Giants -1.5 Runs (+106) at FanDuel

Wager: 1 unit

For our spread pick to win, the Giants will need to win by the amount of the spread or more in order to cover.

Over/Under Pick: Under 7 Total Runs (102) at FanDuel

Wager: 0.5 units

The Diamondbacks have recorded 4.9 runs per game over their last 10. Meanwhile, the Giants have averaged 4.9 runs per game in the same stretch.


TGD Computer Picks

The Game Day's staff computer crunches the numbers to create daily bet picks for sports including NFL, NBA, MLB, NHL, soccer, and more.

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