Reds vs Cardinals Predictions & Best Bets | Picking Against the Spread

Last Updated: Aug 31, 2022

The Cardinals (75-54) will once again pay a visit to the Reds (50-77) in Game 2 of this regular season double header on Wednesday, August 31 at Great American Ball Park in Cincinnati. Each team will be eager to come out on top as they work their way through the final stretch of the regular season. Catch all the action at 6:40 p.m. ET!

For their upcoming game, the Reds have claimed victory against their opponents. In their most recent meeting on Tuesday, the score was 5-1 in favor of the Reds. The Reds had five runs to the Cardinals one run. Be sure to tune in and see how it all unfolds at Great American Ball Park.

Reds vs Cardinals Prediction

The bookmakers at FanDuel think this should be a win for the Cardinals, giving them -240 odds for victory. Conversely, Cincinnati is listed at +194. The predicted number of total runs in this ball game is 9.5.

In their last game on Tuesday, the Reds beat the Cardinals by a score of 5-1. So far this season, the team is currently batting .242 thanks in large part to their top hitter, James Farmer, who has a batting average of .271. Defensively, they carry an ERA of 5.01 and a .985 fielding percentage.

In their last showdown on Tuesday, the Cardinals lost to the Reds by a score of 5-1. So far this season, the team is currently batting .133, thanks in large part to their top hitter, Paul Goldschmidt, who has a batting average of .336. Defensively, they have an ERA of 3.97 and a .988 fielding percentage. Be sure to take a look at our evaluation of the odds and make your choices based on the teams’ recent performances!

Going into this clash, the Reds will play without Antonio Santillan (Back), Lucas Sims (Back), Christian Greene (Shoulder), Justin Dunn (Shoulder), Reinaldo Almora Jr. (Shoulder), Connor Overton (Back), Matthew Reynolds (Hip), Timothy James Zeuch (Back), Robert Dugger (Shoulder), Jeffrey Hoffman (Forearm), Aramis Garcia (Finger), Tyler Stephenson (Clavicle), Justin Wilson (Elbow), Douglas Ashcraft (Biceps), Vladimir Gutierrez (Forearm), Daniel Duarte (Elbow), Joseph Votto (Rotator Cuff), Michael Moustakas (Calf) and Tejay Antone (Elbow). Then, the Cardinals are missing Alexander Reyes (Shoulder), Steven Matz (Knee), Jack Flaherty (Shoulder) and Drew VerHagen (Hip).

Moneyline Pick: Cardinals (-240) at FanDuel

The team is considered the favorite in the betting market. In their previous encounter against these opponents, the Reds got the W 5-1.

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Reds vs Cardinals Betting Odds

  • Moneyline: St. Louis (-240), Cincinnati (+194) at FanDuel
  • Run Line: St. Louis -1.5 (-146), Cincinnati 1.5 (+122) at FanDuel
  • Over/Under: Under 9.5 Runs (-110), Over 9.5 Runs (-110) at FanDuel

View all the top MLB betting odds with our awesome lines comparison feature.

Reds vs Cardinals Betting Trends

  • Win % as favorite: Reds 0.13%, Cardinals 0.58%
  • Win % as underdog: Reds 0.47%, Cardinals 0.27%
  • Win-loss record last 10 games: Cincinnati 4-6, St. Louis 6-4

Runline Pick: Cardinals -1.5 Runs (-146) at FanDuel

Wager: 1 unit

For our spread pick to win, the Cardinals will need to win by the amount of the spread or more in order to cover.

Over/Under Pick: Under 9.5 Total Runs (-110) at FanDuel

Wager: 0.5 units

The Cardinals have recorded 4.5 runs per game over their last 10. Meanwhile, the Reds have averaged 4.5 runs per game in the same stretch.


TGD Computer Picks

The Game Day's staff computer crunches the numbers to create daily bet picks for sports including NFL, NBA, MLB, NHL, soccer, and more.

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