Heisman Trophy Odds & Predictions 2025

Through 10 weeks of the college football season, the Heisman Trophy odds have started to lean toward two quarterbacks from the Big Ten.

These are also just two of three quarterbacks on this list of Heisman favorites on teams that are undefeated.

Below, I’ll discuss the Heisman Trophy best bets, including Ohio State’s Julian Sayin, Indiana’s Fernando Mendoza, and many more.

Top Heisman Candidates 2025

All NCAAF odds used for these Heisman Trophy predictions are current as of Tuesday, Nov. 4, and courtesy of DraftKings Sportsbook.

• Julian Sayin, QB, Ohio State (+175)

• Fernando Mendoza, QB, Indiana (+230)

• Ty Simpson, QB, Alabama (+450)

• Marcel Reed, QB, Texas A&M (+850)

• Gunner Stockton, QB, Georgia (+2200)

• Trinidad Chambliss, QB, Ole Miss (+2500)

• Jeremiah Smith, WR, Ohio State (+2500)

• Diego Pavia, QB, Vanderbilt (+3000)

• Jeremiyah Love, RB, Notre Dame (+4000)

All other Heisman candidates have odds of +5000 or longer.

Who Will Win the Heisman Trophy

Julian Sayin (+175)

In his first year as a starting quarterback, Sayin has led the No. 1-ranked Buckeyes to an 8-0 record.

He has completed 80.7% of his passes for 2,188 yards, 23 touchdowns, and three interceptions.

Sayin leads the country in completion percentage, yards per attempt (10), and is third in passing touchdowns.

Back the Ohio State quarterback to win the Heisman Trophy as your NCAAF bet of the day.

Heisman Trophy Favorites

Fernando Mendoza (+230)

The Hoosiers have been a phenomenal story, and Mendoza is the catalyst.

The California transfer leads the Big Ten in passing touchdowns with 25 through nine games, which ranks second in the country.

Mendoza guided Indiana to a signature road victory over Oregon, and he will deserve consideration for this award if the Hoosiers keep winning.

Ty Simpson (+450)

The Alabama Crimson Tide had a rough start to the season, but they’ve turned things around thanks to Simpson’s play under center.

The redshirt junior quarterback has been keeping the ball out of harm’s way, throwing just one interception through eight games.

Simpson has engineered massive wins over Georgia, Vanderbilt, Missouri, Tennessee, and South Carolina, often coming through in clutch moments for the Tide.

Heisman Trophy Contenders

Marcel Reed (+850)

Heading into Week 10, the Texas A&M Aggies (8-0) are the No. 3 team in the AP Top 25.

Reed has led the Aggies to wins over Notre Dame, Florida, and Arkansas, and he completely dismantled LSU to the point that the Tigers’ head coach, Brian Kelly, was fired.

Reed isn’t the most sensational passer, but his rushing ability (64 carries for 349 yards and six touchdowns) and these massive wins have put him in the Heisman Trophy conversation.

Gunner Stockton (+2200)

We first saw Stockton in relief of Carson Beck in the College Football Playoff last season.

If you told me after that performance that he would lead the SEC in competition percentage (70.3%) through eight games, I wouldn’t have believed you.

Additionally, Stockton has scored seven rushing touchdowns and thrown just two interceptions, leading the Bulldogs to a 7-1 start.

Heisman Trophy Sleepers

Trinidad Chambliss (+2500)

What a story Chambliss has been. His college football career began at Ferris State, where he played from 2022 to 2024.

This season, he started as the backup to Austin Simmons, but got a chance to start due to injury. He owns a 6-1 record in seven starts and has thrown nine touchdown passes, run for six more, and thrown just two interceptions.

He has led Ole Miss to massive wins over LSU and Oklahoma, with his lone loss coming at Georgia 43-35.

Jeremiah Smith (+2500)

Smith is the least likely Heisman Trophy winner pick on this list, especially as a non-quarterback.

Through Week 10, he has caught 55 passes for 725 yards and scored nine touchdowns. Smith has caught a touchdown in all but two games and has posted 119 yards or more in three games.

He’s likely too far down the list in terms of receiving stats to win this award, but he’s worth a mention as the No. 1 wide receiver for Sayin.

Former Heisman Trophy Winners