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NFL Prop Bets Week 5

Frank AmmiranteSenior Sports Writer
@FAmmiranteTFJ
Last Updated: Oct 1, 2025

Betting on props is my preferred strategy because these types of bets are easier to win than point spreads, moneylines, and totals. You can find an edge in this market.

On this page, we’ll include one game prop and three player props for each week of the 2025 NFL season.

So, without further ado, read on to find out my NFL best prop bets for Week 5. I’ve locked onto the Raiders vs Colts game for each of these picks.

Week 5 NFL Prop Bets

NFL Week 5 odds used for prop bets are courtesy of DraftKings Sportsbook, current as of Wednesday, Sept. 1.

Colts: Over 27.5 Points (-108)

DraftKings Sportsbook • WAGER: 1 Unit

The Colts offense has been terrific this season. Shane Steichen deserves votes for Coach of the Year for what he’s done with Daniel Jones.

We’ve seen the Colts perform much better at home, where they’ve scored 29 and 33 points so far this year.

Up next is an exploitable matchup against a Raiders defense that ranks 24th in EPA against the pass this season.

I like that we’re getting below the key number of 28 here, so we’ll ride with the Colts to go Over this team total with our NFL bet of the day.

Week 5 NFL Player Props

Daniel Jones: Over 229.5 Passing Yards (-112) vs Raiders

DraftKings Sportsbook • WAGER: 1 Unit

The market continues to be slow to adjust to Daniel Jones’ passing yards prop this season, listing it below 230 yards once again this week.

Check out Jones’ game log this season:

  • 262 yards
  • 228 yards
  • 316 yards
  • 272 yards

Jones has averaged nine or more yards per attempt in three of four games this season. The big plays have been there, and I don’t expect that to change against a vulnerable Raiders defense.

Jonathan Taylor: Over 86.5 Rushing Yards (-113) vs Raiders

DraftKings Sportsbook • WAGER: 1 Unit

Jonathan Taylor has been phenomenal this season, rushing for 414 yards on 5.4 yards per carry. Just take a look at how dominant he’s been:

  • 76 yards
  • 102 yards
  • 165 yards
  • 71 yards

While 86.5 is a high bar, you have to like Taylor’s chances here due to the projected positive game script. With the Colts as six-point home favorites, that means they should be playing with the lead for most of this game, which would mean more rushing volume.

That gives JT a terrific opportunity to sail Over this number.

Michael Pittman Jr: Over 52.5 Receiving Yards (-113) vs Raiders

DraftKings Sportsbook • WAGER: 1 Unit

Michael Pittman Jr. is reminding the league how good he can be when healthy. After all, he played through a back injury last season.

Take a look at his game log:

  • 41 yards
  • 73 yards
  • 40 yards
  • 80 yards

Up next is an exploitable matchup against a Raiders defense that has given up big games to Quentin Johnston (71 yards), Keenan Allen (61 yards), and Terry McLaurin (74 yards).

Look for Pittman Jr. to eclipse this number here.

Find Top NFL Props

Check out the best player prop bets this week with our props comparison tool. Click on a game below to see all of its prop bets.

Author

Frank Ammirante

Frank Ammirante is a Senior Sports Writer at The Game Day. Previously, he wrote for 4for4 Football and RotoBaller. Frank is a member of the Fantasy Sports Writer's Association while maintaining an active presence within the community. He has competed in industry contests like the Scott Fish Bowl, The Great Fantasy Baseball Invitational, and more. Frank will be making his debut in Tout Wars this year. He's got a diverse sporting background, but specializes in football and baseball.

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