Betting on props can be profitable because it’s a market that isn’t as sharp as point spreads, moneylines, or totals, giving you a chance to find an edge.
On this page, we’ll include one game prop and three player props for each week of the 2025 NFL season.
With that in mind, read on to find out my NFL best prop bets for Week 4. I’ve locked onto the Chargers vs Giants game for each of these picks.
Week 4 NFL Prop Bets
NFL Week 4 odds used for prop bets are courtesy of DraftKings Sportsbook, current as of Thursday, Sept. 25.
Giants: Over 18.5 Points (-112)
DraftKings Sportsbook • WAGER: 1 Unit
The market hasn’t adjusted to the change at quarterback for the Giants.
There’s a legitimate chance that first-round rookie Jaxson Dart acts as a sparkplug for this offense. This is a dual-threat signal-caller who likes to throw it downfield.
With left tackle Andrew Thomas back in the lineup, the pass protection should be improved. The Chargers will be without top pass-rusher Khalil Mack, which also bodes well for this prop.
Lock in the Giants to eclipse this team total with your NFL bet of the day.
Week 4 NFL Player Props
Jaxson Dart: Over 229.5 Passing + Rushing Yards (-112) vs Chargers
DraftKings Sportsbook • WAGER: 1 Unit
We’re getting a pretty low bar on Dart’s passing+rushing yards prop considering how aggressively he likes to play.
We saw the Giants install packages for Dart while Russell Wilson was the starter, which indicates that they plan to call designed runs for him as starter.
This bodes well for his rushing yards output. Add in the fact that the Giants are six-point underdogs here, and you’re likely to see Dart have to dropback more often.
With that in mind, it wouldn’t surprise me to see Dart sail Over this number.
Malik Nabers: Over 63.5 Receiving Yards (-112) vs Chargers
DraftKings Sportsbook • WAGER: 1 Unit
Even though Russ did a good job getting the ball to Malik Nabers downfield against the Cowboys, the move to Dart is huge for the former LSU star’s upside.
We’re getting a low bar at 63.5 receiving yards, as oddsmakers are tempering expectations in Dart’s season debut.
But this is going to be an offense that features a lot of read-pass-options (RPOs), which has the quarterback locking on the first read. Guess who that will be? Yup, Nabers.
This feels like a prop that you can take alternate lines on. It wouldn’t shock me to see 100+ in this one.
Ladd McConkey: Over 62.5 Receiving Yards (-110) at Giants
DraftKings Sportsbook • WAGER: 1 Unit
With how well Quentin Johnston and Keenan Allen have been playing, everyone seems to forget how good Ladd McConkey is.
We’re thankful for that because it’s given us a low bar at 62.5 receiving yards.
The Chargers have been one of the most pass-heavy offenses in the NFL so far this year. It’s time for Justin Herbert to start to get Ladd more involved.
We’ve seen Deebo Samuel and CeeDee Lamb have big games against this Giants defense. Bet on Ladd eating in the slot here.
Find Top NFL Props
Check out the best player prop bets this week with our props comparison tool. Click on a game below to see all of its prop bets.
