MNF Predictions Week 17 | Bills vs Bengals

Frank AmmiranteFantasy Sports & Betting Writer
Posted: Jan 2, 2023Last updated: Jan 5, 2023

Thank you for reading our Monday Night Football predictions all season long.

While the 2022 MNF slate is now complete, you can still keep up with the latest NFL odds and NFL betting tips throughout the remainder of the 2022 NFL regular season and playoffs.

The Buffalo Bills (12-3) look to cement their position as the No. 1 seed in the AFC with a win against the Cincinnati Bengals (11-4) in Week 17.

This is a matchup of two Super Bowl contenders who are among the hottest teams in football. The Bills are currently on a six-game winning streak, while the Bengals have now won seven in a row.

Here’s a look at our favorite Buffalo vs Cincinnati betting tips for Monday Night Football.

Bengals fans: Ohio online betting is live! Find our best Ohio sports betting offers to get started.

Bills vs Bengals Odds

Bills vs Bengals odds are courtesy of Caesars Sportsbook as of 4:30 p.m. EST on Jan. 2.

The Bills are 2.5-point road favorites, which is a bit surprising considering the Bengals’ home-field advantage, but makes sense when you dive deeper.

The total comes in at 50.5 points, which reflects how prolific these two offenses are while also accounting for their stout defenses.

Bills vs Bengals Implied Score

Bills 26.5, Bengals 24

Bookmakers are projecting a close game between two of the best teams in the NFL. They like the Bills to come through in the end.

Take a look at the best Bills odds and Bengals odds for the 2022 NFL season.

Monday Night Football Pick of the Day

Read more on this Bills vs Bengals bet below.

Monday Night Football Matchup

The biggest factor in this game will likely come down to pass protection. Cincinnati suffered a major loss when right tackle La’el Collins suffered a torn ACL in the first quarter against the Patriots in Week 16.

While Joe Burrow was still able to throw for 375 yards, he was sacked twice and threw two interceptions. The Bengals were limited to only 22 points and shut out for the entire second half.

That doesn’t bode well against a Bills defense that has at least two sacks in 13 of their 15 games this season. Buffalo also ranks seventh in Pass DVOA, per Football Outsiders, so this is a tough matchup.

We could see the Bills pressure Burrow and slow down the Bengals’ passing game via their pass rush.

Monday Night Football Prediction

Bills 26, Bengals 20

We’re starting to see the Bills offense round into form, as they’ve eclipsed 30 points in consecutive games after failing to do so in their previous three.

Their running game came alive against the Bears, as Devin Singletary and James Cook combined for 205 rushing yards. If they can continue to run the ball efficiently, this offense will be unstoppable.

When you add in Cincinnati’s pass-protection concerns, you come away feeling confident that Buffalo will take this one.

Monday Night Football Bet Tips

Here are a few betting trends to consider before making your Bills vs Bengals bets:

  • The Bills are 7-7-1 against the spread, and Unders are 10-5 in their games.
  • The Bengals are 12-3 ATS, and Unders are 9-5-1 in their games.
  • Cincinnati may struggle to cope without Collins on the offensive line.

Monday Night Football Best Bets

Bills -2.5 (-110) at Caesars Sportsbook

WAGER: 1 Unit

The line is telling us that oddsmakers feel that Buffalo has the advantage here, as they’re favored despite being on the road.

Look for Buffalo to exploit Cincinnati’s weakness in pass protection.

Want to bet on the Bills? Check out the best NY sportsbooks.

Under 50.5 Points (-110) at Caesars Sportsbook

WAGER: 1 Unit

Both of these teams have trended Under all year long, as they have combined to stay below the number in 19 of their 30 games.

I expect more of the same in this projected close game, especially with Cincinnati having to deal with Buffalo’s pass rush.

Soon you will be able to bet on the Bengals with these Ohio sportsbooks.

Monday Night Football Prop Bet

Bills to Win by 1-6 Points (+290) at Caesars Sportsbook

Wager: 0.5 Unit

The most likely outcome here is that Buffalo wins by 1-6 points. Taking this prop also gives us a win if the Bills only win by one, causing our spread pick to push.

Monday Night Football Same-Game Parlay

Best MNF Same-Game Parlay (+264) at Caesars Sportsbook

  • Bills -2.5 (-110)
  • Under 50.5 Points (-110)

Wager: 1 Unit

I’m confident in the Bills winning a relatively low-scoring game here, so we’ll parlay these two results for a chance at a higher payout.

The +264 odds are nice value when you consider Buffalo’s advantage up front.


Frank Ammirante

Before joining The Game Day, Frank spent three years in the fantasy sports and betting industry, writing for websites like RotoBaller and 4for4football. Frank is an active member of the fantasy baseball and fantasy football community, participating in high-stakes leagues like NFBC/NFFC as well as industry competitions like Scott Fish Bowl, RazzBowl, and TGFBI. Frank is a member of the FSWA and IBWAA. Give him a shout to talk fantasy sports and sports betting.

Related articles

Create Betslip