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MNF Predictions Week 3 | Eagles vs Bears

Last Updated: Sep 23, 2026

Week 3 of the NFL season concludes with an intriguing Monday Night Football matchup between the Philadelphia Eagles and Chicago Bears at Soldier Field.

Philadelphia enters the game with a 2-0 record after a 24-20 comeback win over the Tennessee Titans in Week 2. Jalen Hurts and the Eagles will look to remain undefeated against a Bears team dealing with major uncertainty at quarterback.

Chicago could be forced to start third-string quarterback Case Keenum, with Caleb Williams dealing with a hamstring injury and backup Tyson Bagent in concussion protocol. The Bears managed just three points in their Week 2 loss to the Minnesota Vikings, and having Keenum under center would create another challenge against Philadelphia’s defense.

Keep reading to see the latest Eagles vs. Bears odds and my MNF best bets and predictions for Week 3.

Updated MNF Odds Comparison

All NFL odds used for these Monday Night Football predictions are current as of Wednesday, Sep. 23, and courtesy of DraftKings Sportsbook.

MNF Implied Scores & Team Totals

Eagles 23, Bears 18.5

Oddsmakers are giving Philadelphia the edge on the road, and Chicago’s quarterback situation is a major reason why the Eagles have a clear advantage in this matchup.

The Bears could be forced to start third-string quarterback Case Keenum, with Caleb Williams dealing with a hamstring injury and Tyson Bagent in concussion protocol. That’s a difficult situation against an Eagles defense that has the talent to pressure the quarterback and make life difficult for Chicago’s passing game.

The Bears managed just three points against Minnesota in Week 2, and their offensive struggles could continue if Keenum is forced into the starting lineup. Chicago may need to lean heavily on its running game to keep the Eagles’ defense honest, but that could be difficult if Philadelphia builds an early lead.

The Eagles have enough offensive firepower with Jalen Hurts, Saquon Barkley, and DeVonta Smith to take advantage of Chicago’s quarterback uncertainty. With the Bears potentially starting their third-string quarterback, I wouldn’t be surprised if Philadelphia exceeds its 23-point implied total while Chicago struggles to reach 18.5 points.

Sportsbook Play of the Day

Monday Night Football Predictions

MNF Score Prediction: Eagles 23, Bears 16

Philadelphia has the clear advantage in this matchup, especially with Chicago dealing with significant injuries at quarterback. The Bears could be forced to start third-stringer Case Keenum, with Caleb Williams nursing a hamstring injury and Tyson Bagent in concussion protocol.

That’s a difficult situation against an Eagles defense that has the talent to pressure the quarterback and force mistakes. Chicago managed just three points in its Week 2 loss to Minnesota, and I expect Philadelphia to make life even more difficult for an offense that could be without its top two quarterbacks.

The Eagles are coming off a 24-20 win over Tennessee, improving to 2-0 on the season. While their offense hasn’t been firing on all cylinders, Jalen Hurts and Saquon Barkley give Philadelphia enough firepower to put points on the board against Chicago.

The Bears have the offensive weapons to keep this game competitive, but their quarterback uncertainty makes it difficult to trust them against a strong Philadelphia defense. I expect the Eagles to generate consistent pressure, force Keenum into difficult situations, and prevent Chicago from sustaining drives.

Look for Philadelphia’s defense to take control of this matchup while Hurts and Barkley do enough offensively to secure a comfortable 23-16 road victory on Monday Night Football.

Monday Night Football Bet Tips

Keep these Monday Night Football bet tips and trends in mind before making your Eagles vs. Bears best bets.

  • Philadelphia enters Monday Night Football with a 2-0 record after defeating Tennessee 24-20 in Week 2. The Eagles have enough offensive firepower with Jalen Hurts, Saquon Barkley, and DeVonta Smith to take advantage of Chicago’s quarterback uncertainty.
  • The Bears could be forced to start third-string quarterback Case Keenum, with Caleb Williams dealing with a hamstring injury and Tyson Bagent in concussion protocol. Chicago managed just three points against Minnesota in Week 2, and facing Philadelphia’s talented defense without its top two quarterbacks would make this an even more difficult matchup.
  • Philadelphia’s defensive front could be the difference in this matchup. If Keenum starts, the Eagles should be able to generate pressure and force Chicago into difficult passing situations. The Bears may need to lean heavily on their running game to keep the offense on schedule and avoid obvious passing downs.

Monday Night Football Best Bets

MNF Over/Under Pick: Eagles @ Bears: Under 41.5 Points (-110)

This total opened at 43.5 before dropping to 41.5, and I still like the Under with Chicago potentially starting third-string quarterback Case Keenum.

The Bears managed just three points against Minnesota in Week 2, and facing Philadelphia’s talented defense without Caleb Williams would make things even more difficult.

Chicago could lean heavily on its running game to protect Keenum, shortening the game and limiting possessions for both teams.

Philadelphia should control this matchup, but the Eagles don’t need a huge offensive performance to win comfortably. With Chicago’s quarterback injuries and offensive struggles, I’m backing Under 41.5 points on Monday night.

MNF Pick Against the Spread: Eagles -4.5 (-110) at Bears

Philadelphia has the edge in the trenches, which could be the difference against a Chicago team dealing with significant quarterback injuries.

The Eagles should be able to control the line of scrimmage and establish Saquon Barkley on the ground, keeping their offense in manageable situations.

Chicago’s defense may keep things competitive early, but Philadelphia has the more balanced roster and should be able to wear down the Bears as the game progresses.

With Jalen Hurts capable of extending drives through the air and on the ground, I expect the Eagles to pull away in the second half and cover the 4.5-point spread.

Back Eagles -4.5 with your NFL pick of the day.

Monday Night Football Prop Bet

MNF Prop Bet: Saquon Barkley Over Rushing Yards (Play up to 70.5)

This is a favorable game script for Barkley, with Philadelphia likely to play from ahead against a Chicago team dealing with significant quarterback injuries.

If the Eagles build an early lead, they can lean heavily on Barkley to control the clock and keep the Bears’ offense off the field. That should give him plenty of opportunities to pile up rushing yards, especially in the second half.

Philadelphia’s offensive line should also have the advantage in the trenches, creating opportunities for Barkley to break off some longer runs.

With the Eagles favored to win and likely to establish the running game, I like Barkley to clear 70.5 rushing yards on Monday Night Football.

Monday Night Football Parlay

Best MNF Same-Game Parlay (+168)

  • Eagles ML (-225)
  • Under 41.5 (-115)

This parlay gives me some extra protection on the two straight bets I already like for Monday night.

I’m backing Eagles -4.5 against the spread, but using the moneyline gives Philadelphia some room to win a close game without needing to cover. Chicago’s quarterback injuries give the Eagles a clear advantage, and I expect their defense to make life difficult for the Bears.

The Under also fits with that game script. If Chicago is forced to start third-string quarterback Case Keenum, the Bears could struggle to sustain drives and generate explosive plays against Philadelphia’s defense.

With the Eagles likely to play from ahead, they can lean on Saquon Barkley to control the clock and limit possessions in the second half.

A 23-16 Philadelphia victory would cash both legs, making Eagles ML and Under 41.5 my favorite same-game parlay for Monday Night Football.

Author

Bryan Zarpentine

Bryan is a freelance sports writer and a jack of all trades, covering baseball, football, soccer, and basketball, among other sports. His work has been published at The Sporting News, Audacy, and other well-known sites. Bryan is a graduate of Syracuse University and spends his free time reading, traveling, and attending sporting events.

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