Jaguars vs Chiefs Predictions & Odds

Posted: Nov 7, 2022Last updated: Nov 7, 2022

Patrick Mahomes and the Kansas City Chiefs will play host to Trevor Lawrence and the Jacksonville Jaguars in Week 10 of the 2022 NFL season. The Chiefs are coming off a close 20-17 overtime win against the Titans, while the Jaguars won 27-20 over the Raiders in Week 9.

At 6-2, the Chiefs are sitting atop the loaded AFC West Conference, while the Jaguars are in third place in the AFC South at 3-6.

I’ll be covering some of my betting tips and predictions for this one as Mahomes and the high-powered Kansas City offense looks to roll over the Jaguars. Continue reading for my best bets to target in this one.

All odds are current as of noon ET on Monday, Nov. 7, at FanDuel Sportsbook.

Jaguars vs Chiefs Odds

The Chiefs are 9.5-point favorites as of this writing at Fanduel Sportsbook. That’s the second-largest spread of the Week 10 slate at the moment, just behind just the Eagles, who play host to the Commanders.

While this 9.5-point spread may seem a bit high, I’m expecting the Chiefs to dominate this one. Kansas City could be even bigger favorites by the time kickoff rolls around.

Take a look at the best Jaguars odds and Chiefs odds for the 2022 NFL season.

Jaguars vs Chiefs Implied Totals

Chiefs 29.5, Jaguars 20

As of noon on Monday, the game total is set at 49.5, making this matchup the highest implied total of the week.

Jaguars vs Chiefs Pick of the Day

Read more on this Jaguars vs Chiefs bet below.

Jaguars vs Chiefs Prediction

Chiefs 30, Jaguars 17

For the most part, Mahomes and the Kansas City offense have been healthy all season long. Travis Kelce continues to dominate and is Mahomes’ favorite target to lean on. Kelce has three games with 100-plus yards, and he should be able to have another this week against a weak Jaguars defense.

The Jaguars ended their five-game losing streak over the Raiders, but get one of the worst possible matchups you could ask for on the road against the Chiefs.

Both of these teams have been a bit lucky, avoiding major injuries to key players despite many big names getting hurt this year around the NFL. Last week, both teams had just one name on the injury report. Neither of those players - Jamal Agnew for the Jaguars and Jody Fortson for the Chiefs - have played large roles for their respective teams.

Lawrence and the Jaguars have shown flashes at times this year. Their up-and-coming star running back Travis Etienne is starting to solidify himself as one of the most electric pass-catching backs in the league.

As for Kansas City, JuJu Smith-Schuster is starting to catch on to this Chiefs offense. He caught 10 of 12 targets in Week 9, both season highs. Look for Smith-Schuster to continue getting more involved in this one.

Jaguars vs Chiefs Bet Tips

Here are some Jaguars vs Chiefs betting trends to consider before placing your bets:

  • The Chiefs have won their last five matchups against the Jaguars.
  • The Chiefs are 0-4 against the spread at home this year.
  • The total has gone Under in four of the Jaguars’ last five games.

Jaguars vs Chiefs Best Bets

Chiefs -9.5 (-115) at FanDuel Sportsbook

The Chiefs are not just one of the best teams in a loaded AFC Conference, they’re one of the Super Bowl favorites. Mahomes is playing at his usual MVP-caliber type of play and just continues to get it done, even after the departure of Tyreek Hill.

Jacksonville has definitely shown some promise and improvement since last year, but they still lack discipline and haven’t really found their true identity.

I’m banking on the Chiefs to win this one by multiple scores, reminding everyone that they’re likely to make a deep playoff run this year.

Before placing this bet, get the best Chiefs promo codes.

Under 49.5 Total Points (-110) at FanDuel Sportsbook

With the highest implied total points for Week 10, I’m taking the Under in this one. The biggest reason is that the Jaguars’ total points have gone Under in four of their last five games. The Jaguars also turn the ball over quite a bit. Their 13 giveaways are tied for the fourth-worst mark in the NFL.

Jacksonville is ninth in the NFL in points per game this year at 19.8. The Chiefs’ defense has been steadily improving, and I’m expecting them to neutralize the Jaguars’ offense in this one.

Before placing this bet, get the best Jaguars promo codes.

Jaguars vs Chiefs Props

Check out the best Jaguars vs Chiefs player prop bets this week with our props comparison tool. Click on “Show More Games" below to find the Jacksonville vs Kansas City game and see all of its prop bets.


Aaron Schill

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