Steelers vs Bills Predictions

Last Updated: Oct 3, 2022

If you thought things were already bad in Pittsburgh, it’s about to get much worse.

After losing to the Jets at home and falling to 1-3 on the season, the Steelers will take on Josh Allen and the Bills in Week 5. But will Buffalo overlook their opponent ahead of their rematch with the Kansas City Chiefs?

Find out how we see this one going in our Pittsburgh vs Buffalo best bets and predictions.

Steelers vs Bills Odds

The Bills are listed as 14-point favorites over the Steelers, which is hardly a surprise. Yes, it’s a massive spread, but Pittsburgh hasn’t shown that it can contend with a team of Buffalo’s caliber.

Take a look at the best Steelers odds and Bills odds for the 2022 NFL season.

Steelers vs Bills Implied Totals

Bills 30.5, Steelers 16.5

Oddsmakers have the Bills running up the score and blowing out the Steelers in what’s expected to be the least competitive game on the slate this weekend.

Steelers vs Bills Pick of the Day

Read more on this Steelers vs Bills bet below.

Steelers vs Bills Prediction

Bills 34, Steelers 17

By no means should this be a close game. Buffalo will be playing its second home game of the season against a vastly inferior team. In case you need a refresher, the Bills beat the wheels off of the Titans in a 41-7 victory back in Week 2. Their other three games have all been played on the road.

Meanwhile, the Steelers have recorded just six offensive touchdowns through the first four weeks of the season. Rookie quarterback Kenny Pickett provided a nice spark in Week 4 with two rushing touchdowns after Mike Tomlin removed veteran Mitchell Trubisky from the game at halftime.

Pittsburgh’s offense has more life with Pickett under center, and I don’t doubt that he’ll register a couple of scores in Week 5. But this Steelers defense is highly vulnerable without T.J. Watt, and Pickett’s rookie mistakes will likely lead to some easy scores for Buffalo.

There is some trap game potential here for the Bills — they play at Kansas City in Week 6, where they’ll look to avenge their loss from last year’s Divisional Round — but even an unfocused Bills team is better than this version of the Steelers.

Steelers vs Bills Bet Tips

Here are some Steelers vs Bills betting trends to consider before placing your bets:

  • The Bills are 2-1-1 against the spread, while the Steelers are 1-2-1.
  • Overs have gone 2-2 in Steelers games and 1-3 in Bills games.
  • The Steelers are 0-7 all-time without T.J. Watt.

Steelers vs Bills Best Bets

Bills -14 (-110) at Caesars Sportsbook

This is an enormous spread, but Buffalo can cover it. In victories, their average scoring margin is 19.3 points, which includes wins of 21+ points over the Rams and Titans.

Meanwhile, the Steelers are averaging just 18.5 points per game, and none of their opponents have been as stout defensively as the Bills are.

Before placing this bet, get the best Bills promo codes.

Steelers: OVER 16.5 Points (-105) at Caesars Sportsbook

Pittsburgh’s offense looked snappier with Pickett on the field this past Sunday. He looked more decisive than Trubisky, demonstrated immediate rapport with his receivers, and extended plays with his legs.

Assuming he draws the start, the Steelers will score more than they’re expected to with Pickett in for an entire game, even if the rookie does only offer a slight boost compared to Trubisky.

Want to place this bet on the Steelers? First, find the best Steelers promo codes.


Garrett Chorpenning

Garrett Chorpenning is the Lead NBA Editor for The Game Day. His previous work includes covering the LA Clippers for Sports Illustrated and FanSided. He graduated from Ball State University in 2021.

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