After winning their first five games to start off the 2023 NFL season, the San Francisco 49ers have since dropped three straight. They’ll try to get back on track with a road victory against Trevor Lawrence and the 6-2 Jacksonville Jaguars.
In contrast to the 49ers, the Jaguars have now won five consecutive games after starting the season 1-2 and have established themselves as one of the best teams in the AFC. Could this be a potential Super Bowl preview in Week 10?
49ers vs Jaguars Odds
NFL odds used for this San Francisco vs Jacksonville preview were found at FanDuel Sportsbook and are current as of Tuesday, Nov. 7, at 10:30 ET.
- Moneyline: 49ers (-164) • Jaguars (+138)
- Spread: 49ers -3 (-110) • Jaguars +3 (-110)
- Total Points: Over 44.5 (-115) • Under 44.5 (-105)
- Implied Score: 49ers 23.5, Jaguars 21.5
49ers vs Jaguars Predictions
Score Pick: Jaguars 27, 49ers 20
The Jaguars have been rolling ever since the division-rival Houston Texans beat them 37-17 in Week 3. They’ve now defeated five straight opponents by an average margin of victory of 11.0 points per game.
Travis Etienne Jr. has been the driving force for the Jacksonville offense in recent weeks, scoring seven touchdowns in the team’s last four games. Expect him to be featured early and often as the Jaguars look to keep pace with the Baltimore Ravens and Kansas City Chiefs atop the AFC standings in hopes of securing a playoff bye.
49ers vs Jaguars Best Bets & Props
Jaguars +3 (-108)
DraftKings Sportsbook • WAGER: 2 units
Lawrence and the Jaguars continue to find ways to win. Yet they’re being given three points on their home field against a team that has lost three in a row. They have covered the spread in each of their past five games and now face a 49ers team that has failed to exceed 17 points in their previous two road games.
The Jaguars can win this game outright, so getting three points when backing them makes this my NFL bet of the day.
Jaguars Over 2.5 Total Touchdowns (+110)
DraftKings Sportsbook • WAGER: 1 unit
During the Jaguars’ five-game win streak, the offense has been firing on all cylinders. In that span, they have scored at least three touchdowns in three games. Etienne has actually been a TD away from eclipsing this total individually in three of the last four games, which bodes well for the Jaguars’ chances of doing so as a unit.
Coming off a bye in Week 9, head coach Doug Pederson will have had two weeks to prepare his team for this showdown with the 49ers. Expect him to have his offense primed to score three-plus touchdowns.
Jaguars Over 25.5 (+195)
DraftKings Sportsbook • WAGER: 0.5 units
As previously mentioned, the Jaguars have been red hot offensively during their winning streak and will have an opportunity to keep it rolling in Week 10. They’ve averaged a gaudy 27.2 points per game over their past five and are now expected to add trade-deadline acquisition Ezra Cleveland to their offensive line.
Given the odds, this is great value and a worthy investment to make in a team that was playing its best football of the season before the Week 9 bye.
49ers vs Jaguars Same Game Parlay
49ers vs Jaguars SGP (+267)
DraftKings Sportsbook • WAGER: 0.5 units
- Jaguars +3 (-108)
- Over 45 (-110)
Although the 49ers failed to score more than 17 points in each of their past two contests, they still rank fourth in the league in points per game (27.3). This is an elite offense that’s filled with playmakers and could potentially be welcoming back former All-Pro wide receiver Deebo Samuel.
The Jaguars have not only won each of their past five games, but they’ve also covered the spread in all of them. Expect more of the same in this potential Super Bowl preview between two of the NFL’s best teams.