Checking NFL Week 18 early lines will give prospective football bettors a solid idea of trends that the sportsbooks and the public will folow.
To offer our NFL readers perspective, we’ve gathered some Week 18 NFL Opening Lines and Odds, including moneyline, against the spread, Over/Under, and implied total points score information to start your betting off right.
All NFL gameday odds and lines are current as of 9:00 p.m. ET on Sunday, January 2, and provided by Caesars Sportsbook (unless otherwise specified).
New York Jets @ Buffalo Bills Early Lines
- Moneyline: Jets (+800), Bills (-1400)
- Spread: Jets +17 (-110), Bills -17 (-110)
- Over/Under Points Total: Over 45.5 (-110), Under 45.5 (-110)
- Implied Score: Bills 31.25, Jets 14.25
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Green Bay Packers @ Detroit Lions Early Lines
- Moneyline: TBD
- Spread: TBD
- Over/Under Points Total: TBD
- Implied Score: TBD
Indianapolis Colts @ Jacksonville Jaguars Early Lines
- Moneyline: Colts (-1000) @ Jaguars (+650)
- Spread: Colts -14.5 (-110) @ Jaguars +14.5 (-110)
- Over/Under Points Total: Over 44 (-110), Under 44 (-110)
- Implied Score: Colts 29.25, Jaguars 14.75
Tennessee Titans @ Houston Texans Early Lines
- Moneyline: Titans (-550), Texans (+400)
- Spread: Titans -10.5 (-110), Texans +10.5 (-110)
- Over/Under Points Total: Over 43 (-110), Under 43 (-110)
- Implied Score: Titans 26.75, Texans 16.25
Chicago Bears @ Minnesota Vikings Early Lines
- Moneyline: Bears (-110), Vikings (-110)
- Spread: Bears -1 (-110), Vikings +1 (-110)
- Over/Under Points Total: TBD
- Implied Score: TBD
Read all of our NFL betting picks ahead of Week 18.
Carolina Panthers @ Tampa Bay Buccaneers Early Lines
- Moneyline: Panthers (+350), Buccaneers (-450)
- Spread: Panthers +9.5 (-110), Buccaneers -9.5 (-110)
- Over/Under Points Total: Over 42.5 (-110), Under 42.5 (-110)
- Implied Score: Buccaneers 26, Panthers 16.5

Tom Brady’s Tampa Bay Buccaneers should pile on points against the Carolina Panthers as they try to swipe the No. 1 NFC seed in Week 18. (Image: USA TODAY Sports)
Washington Football Team @ New York Giants Early Lines
- Moneyline: Washington (-290), Giants (+235)
- Spread: Washington -6.5 (-110), Giants +6.5 (-110)
- Over/Under Points Total: Over 39 (-110), Under 39 (-110)
- Implied Score: Washington 22.75, Giants 16.25
New Orleans Saints @ Atlanta Falcons Early Lines
- Moneyline: Saints (-200), Falcons (+170)
- Spread: Saints -4.5 (-110), Falcons +4.5 (-110)
- Over/Under Points Total: Over 40 (-110), Under 40 (-110)
- Implied Score: Saints 22.25, Falcons 17.75
Cincinnati Bengals @ Cleveland Browns Early Lines
- Moneyline: Bengals (+130), Browns (-150)
- Spread: Bengals +3 (-115), Browns -3 (-105)
- Over/Under Points Total: Over 44 (-110), Under 44 (-110)
- Implied Score: Browns 23.5, Bengals 20.5
BEST BET: Bengals Moneyline (+130)
Really? Cleveland is favored? Is this just because of the Betty White Hot In Cleveland karma?
I know Cincy is on the road, but the Bengals still have an outside shot to earn the top seed in the AFC. The Browns are eliminated from the postseason.
This is a truly odd opening line that we should pounce on immediately.
Pittsburgh Steelers @ Baltimore Ravens Early Lines
- Moneyline: Steelers (+175), Ravens (-210)
- Spread: Steelers +4.5 (-110), Ravens -4.5 (-110)
- Over/Under Points Total: Over 42 (-110), Under 42 (-110)
- Implied Score: Ravens 23.25, Steelers 18.75
New England Patriots @ Miami Dolphins Early Lines
- Moneyline: Patriots (-250), Dolphins (+205)
- Spread: Patriots -5.5 (-110), Dolphins +5.5 (-110)
- Over/Under Points Total: Over 39.5 (-110), Under 39.5 (-110)
- Implied Score: Patriots 22.5, Dolphins 17
BET PICK: Patriots Cover -5.5 @ Dolphins (-110)
New England’s tussle with the Buffalo Bills for the AFC East crown will come down to the final weekend, and while the Dolphins eked out a victory over New England in Week 1, don’t expect a repeat.
Mac Jones‘ Pats are 6-1 on the road, and a tandem run game of Damien Harris and Rhamondre Stevenson should help New England control the tempo.
Dallas Cowboys @ Philadelphia Eagles Early Lines
- Moneyline: TBD
- Spread: Cowboys -2.5 (-110), Eagles +2.5 (-110)
- Over/Under Points Total: Over 41 (-110), Under 41 (-110)
- Implied Score: Cowboys 21.75, Eagles 19.25
Seattle Seahawks @ Arizona Cardinals Early Lines
- Moneyline: Seahawks (+235), Cardinals (-290)
- Spread: Seahawks +6.5 (-110), Cardinals -6.5 (-110)
- Over/Under Points Total: Over 48 (-110), Under 48 (-110)
- Implied Score: Cardinals 27.25, Seahawks 20.75
San Francisco 49ers @ Los Angeles Rams Early Lines
- Moneyline: 49ers (+205), Rams (-250)
- Spread: 49ers +5.5 (-110), Rams -5.5 (-110)
- Over/Under Points Total: Over 44.5 (-110), Under 44.5 (-110)
- Implied Score: Rams 25, 49ers 19.5
Kansas City Chiefs @ Denver Broncos Early Lines
- Moneyline: TBD
- Spread: Chiefs -10 (-110), Broncos +10 (-110)
- Over/Under Points Total: Over 44.5 (-110), Under 44.5 (-110)
- Implied Score: Chiefs 27.25, Broncos 17.25
Los Angeles Chargers @ Las Vegas Raiders Early Lines
- Moneyline: Chargers (-150), Raiders (+130)
- Spread: Chargers -3 (-105), Raiders +3 (-115)
- Over/Under Points Total: Over 48.5 (-110), Under 48.5 (-110)
- Implied Score: Chargers 25.75, Raiders 22.75
BEST BET: Chargers @ Raiders OVER 48.5 (-110)
One of the heavy favorites to be flexed into either one leg of the Saturday doubleheader or Sunday Night Football due to its “win and in" status, this AFC West clash will be one of Week 18’s featured matchups.
Allegiant Stadium isn’t too much of a homefield advantage for the Raiders, and if TE Darren Waller (COVID-19) returns from the sidelines, the Raiders should have a more robust playmaking corps to complement Hunter Renfrow and Josh Jacobs.
The Chargers’ offense, meanwhile, kept rolling in Week on the arm of Justin Herbert and legs of Austin Ekeler.