NFL Week 13 Parlays Picks & Predictions | NFL Play of the Day

Frank AmmiranteSenior Sports Writer
Last Updated: Nov 30, 2021

It was a tough week in parlay betting. We hit the Raiders moneyline on Thanksgiving, but the Lions and Saints let us down. Luckily, we bounced back with a winning day on Sunday.

Let’s dive in to find my favorite parlay bets for Week 13 in the NFL pick of the day series.

Please note that all NFL gameday odds are from Caesars Sportsbook and are current as of Tuesday, November 30, at 12:15 p.m. ET.

Best NFL Parlay Week 13

NFL Week 13 Top Parlay Picks

Wager: 2 Units To Win 11.92 Units (+596) at Caesars

  • Arizona Cardinals & Chicago Bears Under 45.5 Total Points (-110)
  • San Francisco 49ers & Seattle Seahawks Under 45.5 Total Points (-110)
  • Minnesota Vikings & Detroit Lions Under 46.5 Total Points (-110)

NFL Week 13 Parlay

Arizona Cardinals & Chicago Bears Under 45.5 Total Points (-110) at Caesars

The Under is 6-5 in Arizona Cardinals games and 8-3 in Chicago Bears games. This will likely be Kyler Murray‘s first start in a month, so we could see some rust in this Arizona offense.

There’s a good chance that we see Andy Dalton starting for the Bears once again. This is a tough matchup against a strong Cardinals defense that ranks third in pass DVOA and fifth in Adjusted Sack Rate. Dalton could find himself under duress throughout this game.

The Cardinals are eight-point road favorites in this game, giving the Bears an implied total of only 19.0 points. Arizona is likely to control this game, making it difficult for Chicago to score enough points to push this Over.

This total opened at 46.5 and has already moved down to 45.5. Go with the Under here.

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San Francisco 49ers & Seattle Seahawks Under 45.5 Total Points (-110) at Caesars

The Under is 6-5 in both San Francisco 49ers and Seattle Seahawks games. The 49ers are rolling right now, outscoring opponents by 59 points during their current three-game winning streak.

The Seahawks have really struggled since Russell Wilson has returned from injury, scoring only 30 points in their current three-game losing streak.

Both teams play at a slow pace. The 49ers have a strong running game with the ability to sustain long drives, which bodes well for the Under.

Minnesota Vikings and Detroit Lions Under 46.5 Total Points (-110) at Caesars

The Under is 5-6 in Minnesota Vikings games and 8-3 in Detroit Lions games. The Lions have scored fewer than 20 points in 10 of their 11 games this season.

The Vikings have a good pass defense, ranking No. 10 in pass DVOA, but they’re vulnerable on the ground (No. 29 in rush DVOA). The Lions have been run-heavy since head coach Dan Campbell took over play-calling duties.

If Detroit can find success on the ground, that’s great news for the Under.

The Lions’ defense has also been better lately, holding opponents to a combined 45 points in their last three games. The Under looks good here, so feel comfortable making this your NFL bet of the day.

D'Andre Swift, RB, Detroit Lions

The Detroit Lions will likely struggle to score against the Minnesota Vikings, especially if running back D’Andre Swift is unable to go. (Image: USA TODAY Sports)

NFL Week 13 Longshot Parlay Prediction

Wager: 1 Unit To Win 11.67 Units (+1167) at Caesars

  • Los Angeles Chargers Moneyline (+140) @ Cincinnati Bengals
  • New York Giants Moneyline (+140) @ Miami Dolphins
  • Washington Football Team Moneyline (+120) @ Las Vegas Raiders

NFL Week 13 Longshot Parlay

Los Angeles Chargers Moneyline (+140) @ Cincinnati Bengals at Caesars

Here we have a battle of two of the most impressive young quarterbacks in the NFL in Justin Herbert and Joe Burrow. The Chargers have the firepower to keep pace with the Bengals with studs like Austin Ekeler, Keenan Allen, and Mike Williams.

Los Angeles is in dire need of a win here after dropping two of their last three games. I think that this team is better than their current 6-5 record, which makes them a solid value at plus money as road underdogs.

The risk here is that red-hot Bengals running back Joe Mixon can exploit this league-worst run defense (Chargers rank No. 32 in rush DVOA), but I like going with the value here on the comparable team.

New York Giants Moneyline (+140) @ Miami Dolphins at Caesars

The New York Giants are coming off a big divisional win over the Philadelphia Eagles. New play-caller Freddie Kitchens allowed quarterback Daniel Jones to spread his wings on the ground, who rushed for 30 yards after combining for 39 yards in his previous three games.

The Giants (4-7) are better than their record, and they’ve played in a bunch of competitive games this season. While the Miami Dolphins (5-7) are red-hot having won four games in a row, they’re still a comparable team to the Giants.

I’ll roll with the value on the road team in this inter-conference game.

Washington Football Team Moneyline (+120) @ Las Vegas Raiders at Caesars

The Washington Football Team is red-hot, currently riding a three-game winning streak. Their defense is finally performing towards expectations, allowing only 55 points in their last three games.

Washington has found an identity with the running game, leading long drives to control the clock. Running back Antonio Gibson looks healthy, coming off a 36-touch game against the Seahawks. The team also has Curtis Samuel and Logan Thomas back, so it’s all hands on deck on offense.

The Las Vegas Raiders are coming off an upset win against the Dallas Cowboys, but this team will be without their best weapon in tight end Darren Waller.

I’ll go with the hot team at plus money in Washington here.

Same Game Parlay Picks NFL Week 13

Indianapolis Colts @ Houston Texans

Wager: 1 Unit To Win 2.64 Units (+264) at Caesars

  • Houston Texans +9 (-110)
  • Total Points Under 46 (-110)

The Houston Texans (2-9) are one of the worst teams in the NFL, but they’re a much scrappier team with Tyrod Taylor under center. We just saw them upset the division rival Tennessee Titans two weeks ago.

The Indianapolis Colts (6-6) are much better than their record with a dominant running game led by Jonathan Taylor. This plays well against Houston’s biggest weakness: run defense (No. 25 in rush DVOA).

However, nine points is a lot for a road team in a divisional game. The Texans have proven to be able to keep games close against division rivals this season, so I’ll take the home underdog here.

I like going with the Under because I expect the Colts to lean on their running game, which would slow the game down. The Under is 7-4 in Texans’ games and I expect this team to try to play at a slow pace as well.

Frank Ammirante’s 2021 NFL Parlay Betting Record: 5-34, -1.51 Units

Thanks for reading our NFL Week 13 Parlays Picks & Predictions! For more NFL Week 13 betting tips, check out our NFL Week 13 Best Bets.


Frank Ammirante

Frank Ammirante is a Senior Sports Writer at The Game Day. Previously, he wrote for 4for4 Football and RotoBaller. Frank is a member of the Fantasy Sports Writer's Association while maintaining an active presence within the community. He has competed in industry contests like the Scott Fish Bowl, The Great Fantasy Baseball Invitational, and more. Frank will be making his debut in Tout Wars this year. He's got a diverse sporting background, but specializes in football and baseball.

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