The Indianapolis Colts visit the Buffalo Bills at New Era Field on Saturday at 1:05 p.m ET. Here’s our complete guide to Colts-Bills Bet Tips. Odds and lines for Colts-Bills picks are from PointsBet, current as of Tuesday at 4 p.m. ET.
Indianapolis Colts (11-5) at Buffalo Bills (13-3)
Colts-Bills Bet Tips & Colts-Bills Picks
Odds & Betting Lines for Colts-Bills Picks
- Against The Spread: Bills -6.5 (-110)/Colts +6.5 (-110)
- Moneyline: Bills (-301)/Colts (+240)
- Total: 51 — Over 51 (-115)/Under 51 (-105)
- Implied Team Totals: Bills 28.75, Colts 22.25