NFL Week 3 Prop Bets – Best NFL Prop Predictions & Picks Today

Last Updated: Sep 22, 2021

Let’s start with a flex.

If you followed NFL prop bets posted in this weekly staple for Week 2, you went 6-1 one last weekend. Not too shabby.

Like an elite quarterback, however, we must operate with a short memory regardless of the results — good, bad, or in between. And with the NFL season wasting no time delivering a plethora of compelling games, we must stay sharp.

While there are delightful games to be found up and down the slate, the NFC’s elite will clash in two separate games to provide some clarity. The Tampa Bay Buccaneers travel to Los Angeles to take on the Rams, and the San Francisco 49ers will welcome the Green Bay Packers into town.

After a strong opening, let’s keep the prop bet heater in motion. Here are our betting tips for Week 3.

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NFL Week 3 Best Prop Bets

Arizona Cardinals at Jacksonville Jaguars

Jacksonville Jaguars Under 21.5 Points (-105) at DraftKings

To be clear, I am not nearly as down on the Jaguars as their fans likely are after only two weeks.

Trevor Lawrence looks like a rookie, which is to be expected given the talent around him. And although Arizona’s defense has struggled early, I still feel like Jacksonville will remain a work in progress.

Outside of the opening sequence, Jacksonville’s offense struggled last weekend as well. That will be the case once again.

Under 6 Touchdowns (-105) at DraftKings

Although I question just how much offense the Jaguars will generate, that doesn’t mean they won’t compete in this game. Kyler Murray is always capable of scoring points, although we saw a much better effort at home in Week 2 after the first week.

The Cardinals will generate offense — more offense than the Jags — in a win. But it will be a lower-scoring game than expected.

Tampa Bay Buccaneers at Los Angeles Rams

Tampa Bay Buccaneers Over 28.5 Points (-105) at DraftKings

There are just too many weapons. Plain and simple. It doesn’t matter when they play, where they play or the team they play. As long as Tom Brady is healthy and upright — which his offensive line has done a brilliant job making sure happens thus far — the Tampa Bay offense will do its part.

As someone very invested in Mike Evans from a fantasy football perspective, I hope the production feeds his way. The allure with this bet and Tampa Bay is general, however, is just how many options they have.

Brady gets 4 more touchdowns and nearly hits this over himself.

Los Angeles Rams Over 6.5 First-Quarter Points (-115) at DraftKings

With a Total of more than 55 points, I expect this game to feature plenty of touchdowns. And the Los Angeles Rams, with so many weapons as well, have a chance to go blow-for-blow with the reigning Super Bowl champions.

A three-point win on the road against the Colts shouldn’t be viewed as a negative. Coming home, having seen how well the team played in the opener, inspires plenty of confidence. I don’t expect Matthew Stafford to take long to score.

This game could be (and likely will be) a great deal of fun, which is reflected in the NFL gameday odds.

Tom Brady, QB, Tampa Bay Buccaneers

Tom Brady has been terrific to begin the season, and he’s about to face his biggest test of the year to date when the Tampa Bay Buccaneers take on the Los Angeles Rams.

Washington Football Team at Buffalo Bills

Washington Football Team Over 18.5 Total Points (-110) at DraftKings

Last week wasn’t perfect for Taylor Heinicke. In fact, his final interception very nearly — and likely should have — cost Washington the game.

But lost in the madness of a weird football outcome was a quality football game from a backup QB who has showed promise in small doses, and I think Heinicke will do that again. While the Bills’ defense was great against the Dolphins, the situation, with Tua Tagovailoa getting hurt early, unquestionably played an impact.

Washington musters up enough offense to hit the over.

Washington Football Team Over 2.5 First-Quarter Points (-115) at DraftKings

Get a field goal on the road early on. It’s that simple. With the reasoning mentioned above, I expect Washington to find a way to move the ball.

I also think the seasoning from last week, something Washington’s QB hasn’t had much of, will help.

It’s not just Heinicke. Running back Antonio Gibson and wideout Terry McLaurin give WFT ample weapons. While the Bills have allowed only 16 points in two games, I expect Washington to double that figure (and then some) this week, making this our NFL bet of the day.

Best NFL Prop Bets Today

San Francisco 49ers vs. Green Bay Packers

Green Bay Packers Under 3.5 First-Quarter Points (-145) at DraftKings

Will Green Bay score a touchdown in the first quarter on Sunday night in the first 15 minutes? That’s the question, and the answers might be somewhat skewed.

On Monday night, the Packers’ offense came to life. While Aaron Rodgers made a few dazzling throws, the fact that Aaron Jones caught three touchdowns, while good for those fantasy managers, is still a concern.

A road game in California presents trouble. While Green Bay will be competitive, it’ll be a bit of a slog.

San Francisco 49ers Under 13.5 First-Half Points (-105)

So, I like the under. By now, that should make sense.

While so much of this matchup will be about Kyle Shanahan vs. Rodgers, the environment coupled with the talent on defense could make this a lower scoring game than most expect.

The Total is Under 50 points, which feels underwhelming in today’s NFL. While it’ll be impossible to keep these offenses off the board, they both feel slightly overrated in the moment.

Eventually they will get going, but it’ll take some time, making this a strong pick of the day.

Thanks for reading our NFL Week 3 Best Prop Bets! For more NFL betting tips, check out our NFL Week 3 Best Bets & Predictions.


Adam Kramer

Adam Kramer is an NFL, college football, and gambling analyst for The Game Day. While college football has long been his calling, he’s also covered sports such as boxing, horse racing, and baseball at The Game Day and in other places. He’s also written for Bleacher Report, VSiN, and various other outlets over the past decade-plus.

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