Best MLB Prop Bets Today: MLB Player Prop Bets 9/16/21

Last Updated: Sep 16, 2021

For Thursday, Mike Barner has your MLB Betting Picks of the Day: Best Baseball Props Today 9/16/21. All odds for our MLB player prop picks today were obtained from PointsBet.

Thursday brings nine games across baseball, most of which have early start times. With my season record sitting at 27-17 (+8.12 units), let’s discuss three of our best MLB prop bets today that could prove to be profitable.

Best MLB Player Prop Pick Today

For in-depth analysis of this MLB bet of the day and other MLB player prop bets, continue reading.

MLB Props Of The Day: Best Baseball Props Today 9/16/21

Nelson Cruz, Tampa Bay Rays vs. Detroit Tigers

To Record An RBI (+100)

Wager: 1 unit (win would pay 2 units)

The Detroit Tigers will send left-hander Tyler Alexander to the mound tonight, who’s been decent this year but has really struggled against righties (.812 OPS). He’s also given up 14 home runs across 83 2/3 innings this season, 12 of which have come against right-handed hitters. We could be looking at a productive evening for Nelson Cruz, who has a career 153 wRC+ against southpaws and is enjoying a strong September with a .976 OPS and 12 RBIs in 14 games this month.

Mike Zunino, Tampa Bay Rays vs. Detroit Tigers

To Record A Hit (-150)

Wager: 1 unit (win would pay 1.67 units)

Cruz isn’t the only player in Tampa Bay’s lineup with favorable splits against lefties. While Mike Zunino is hitting only .127 versus right-handed pitchers this season, he’s raked lefties to the tune of a .346 average over 118 plate appearances. With better numbers against southpaws throughout his career as well, taking a chance on Zunino to record a base knock is one of our best MLB prop picks today.

Framber Valdez, Houston Astros at Texas Rangers

To Record A Win (-115)

Wager: 0.5 units (win would pay 0.93 units)

Framber Valdez has had plenty of success against the Texas Rangers, winning both of his starts against them this year while allowing just two earned runs over 13 innings. Valdez is having a strong season overall with a 3.26 ERA and a 3.96 FIP for the Houston Astros, who should be able to give him plenty of run support with their potent lineup. With wins in 10 of his 19 starts this year, Valdez is a good bet to record another W against one of the worst teams in the league.


Mike Barner

Mike started covering fantasy sports in 2007. In addition to The Game Day, Mike has written for RotoWire, Sportsline, Sports Illustrated, DK Live and RealTime Fantasy Sports. In 2018, he was a finalist for the 2018 FSWA Basketball Writer of the Year award. .

Related articles


Get $1,500 in Bonus Bets

5 stars

Bet $5 & Get $150 in Bonus Bets or First Bet Safety Net

5 stars

Bet $5, Get $200 in Bonus Bets

5 stars

Get A Bonus Bet Up to $1,000

5 stars

Get $150 in Bonus Bets

5 stars

Get Up To $250 2nd Chance Bonus Bet

5 stars

If you or someone you know has a gambling problem and wants help, please call 1-800-GAMBLER.

21+ and present in OH. Gambling Problem? Call or text 1-800-GAMBLER (CO, DC, IL, IN, LA, MD, MS, NJ, OH, PA, TN, VA, WV, WY).

Call 877-8-HOPENY or text HOPENY (467369) (NY).

Please Gamble Responsibly. Call 1-800-NEXT-STEP (AZ), 1-800-522-4700 (KS, NV), 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-270-7117 for confidential help (MI).

All betting content on is exclusively intended for audience members 21 years and older who are permitted to gamble in legal states. The Game Day may earn revenue from site visitor referrals to betting services.

Responsible Gaming: Many sportsbooks offer ways to encourage responsible gaming, including the establishment of limits to deposits, spending, and time dedicated to betting.

The Game Day is a TGD Marketing Ltd. endeavor.