Michigan vs Ohio State Predictions & Odds

Lance PattonPromotions Creator & Editor
Last Updated: Nov 26, 2022

Everything is on the line for the Ohio State Buckeyes and Michigan Wolverines when they meet up for the 2022 edition of one of the all-time college football rivalries.

Ohio State trailed at half to Maryland but earned a 13-point win after a defensive touchdown in the final seconds. It wasn’t their best performance of the year, but they kept the undefeated season intact.

Michigan narrowly escaped with a win against Illinois after scoring three 4th-quarter field goals - two in the final three minutes - to remain undefeated with a 19-17 win.

Both squads winning sets up a matchup of undefeated teams and one of the most highly anticipated matchups in recent history.

The winner of this year’s contest between two of the top teams in the nation will represent the Big Ten East in the Big Ten Championship and remain on the inside track to reaching the College Football Playoff — and possibly winning it.

Continue reading for more predictions, CFB Odds, and betting tips for Michigan vs Ohio State.

Michigan vs Ohio State Odds

After both teams struggled in their last outings, Ohio State is now up to a 7.5-point favorite at home as of the odds on the Caesars Sportsbook on Nov. 21 at noon ET.

The total has also dropped around 2.5 points and is now listed at 57 for these two CFB National Championship odds contenders.

Michigan vs Ohio State Implied Totals

Ohio State 32.25, Michigan 24.75

The implied total at Caesars as of Monday, Nov. 21, at noon ET has Ohio State winning by a touchdown and the hook with the total set at 57.

This number may be surprisingly lopsided to some, but Ohio State’s high-powered offense at home is enough to give them a significant edge from the oddsmakers’ perspective in this game.

Michigan vs Ohio State Pick of the Day

Read more about this Michigan vs Ohio bet below.

Michigan vs Ohio State Prediction

Ohio State 35, Michigan 31

Both of these offenses are excellent, and they both find success in different methods.

Michigan is going to hand the ball off between 30-40 times a game and lean on opposing defenses with a big and nasty offensive line. As they should with a Heisman candidate in running back Blake Corum, who has rushed for 1,457 yards and 18 touchdowns on nearly six yards per carry this season.

Corum left last week’s game against Illinois and received just one carry in the second half, and he is questionable heading into this week.

Ohio State is going to space teams out and throw it around the field with C.J. Stroud and multiple wide receivers with NFL futures.

Stroud is the favorite in Heisman winner odds after throwing for 2,991 yards and 35 touchdowns through the opening 11 games. He leads the nation in touchdown passes with an 89.7 QBR.

Defensively, both teams are sound, but the advantage goes to Michigan, who has allowed just 11.2 points and 232.8 yards per game this season.

Michigan won this game last year by bullying the Ohio State front seven and running the ball effectively, but the Buckeyes have taken major steps since that game to improve their defense.

Michigan vs Ohio State Bet Tips

Before you make your CFB Week 13 bets, consider these Michigan vs Ohio State betting trends before placing your wagers:

  • Ohio State has won eight of the last nine matchups and 15 of the last 17.
  • The winner of Michigan-Ohio State has won the Big Ten East in seven of the last eight years.
  • Ohio State is No. 1 and Michigan is No. 2 in Points Per Game differential this season.
  • Michigan hasn’t won back-to-back games against Ohio State since 1999 and 2000.

Michigan vs Ohio State Best Bets

Michigan +9.5 (-110) at FanDuel Sportsbook

WAGER: 1 Unit

Although I do think Ohio State comes away with the win, this is just a case of too many points.

As long as Corum gives it a go, this rushing attack will have a lot of success against the Ohio State defense. and will never be out of the game.

Not only will they be able to score, but the run-heavy offense will keep the Ohio State offense off the field, which is enough to keep this game close.

There’s no reason the Wolverines won’t have a chance to win this game late, so I’ll confidently take the 9.5-points spread.

Total Points Over 57 Points (-110) at Caesars Sportsbook

WAGER: 1 Unit

Two Heisman Trophy candidates and two of the best offenses in the country.

Michigan is going to run the ball effectively and try to recreate the game plan from last season, and Ohio State’s offense is simply too talented to be slowed down for long.

This game goes back and forth for four quarters with the offenses finding plenty of success to take this total Over.

Michigan vs Ohio State Props

Michigan To Win Big Ten Championship (+300) at DraftKings Sportsbook

WAGER: 1 Unit

One thing to consider if you think Michigan will win this game is taking them to win the Big Ten Championship, rather than just taking the moneyline.

A +300 moneyline generally would correlate to a spread of about 10 points. With this spread at 7.5, the moneyline of this game at DraftKings is +250.

And if Michigan does beat Ohio State, they’ll likely be in the range of a three-touchdown favorite in the Big Ten Championship.

This also gives you the opportunity to hedge, or even middle, if you decide the Big Ten West representative has a chance to keep it close or win the Big Ten Championship.


Lance Patton

Lance Patton is the Promotions Creator & Editor for The Game Day and also creates content for the NFL, college football, and college basketball. Before joining The Game Day, Lance did freelance work for a variety of sports betting websites as well as covering the Iowa Hawkeyes for FanSided.

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