Duke vs. Michigan State Predictions | Best Bets & Odds

Two coaching legends square off for one final time as No. 2 Duke will face off against seventh-seeded Michigan State in the West Region second-round game in Greenville, South Carolina.

The Blue Devils handily took care of No. 15 Cal-Fullerton on Friday night. Led by national player of the year candidate Paolo Banchero, who scored a game-high 17 points and chipped in 10 rebounds, the Blue Devils won their first tournament game for the sixth straight NCAA appearance.

The Spartans are back in the second round for the fourth time in five seasons thanks to a 74-73 win over upstart Davidson on Friday night. Tom Izzo‘s team has only advanced past its second tournament game once in that span, in 2019 when Michigan State reached the Final Four.

Duke vs. Michigan State Odds

Duke vs Michigan State/Davidson odds are provided by Caesars and are current as of Saturday, March 19 at 2 p.m. ET. 

  • Moneyline: Duke (-280) vs Michigan State (+230)
  • Spread: Duke -6.5 (-110) vs Michigan State +6.5 (-110)
  • Over/Under: Over 144.5 (-110) / Under 144.5 (-110)
  • Implied Score: Duke 75.5, Michigan State 69

Basketball Betting Play of the Day

Slam home your basketball bets with BetMGM’s welcome offer: New BetMGM Sportsbook customers can bet $10 to win $200 in free bets.

Make a $10 moneyline bet on any game. If either team makes a three-point basket, you’ll win!

🏀 NBA Bet $10, Win $200: Click here and use promo code TGDSPECIAL.

🏀 College Basketball Bet $10, Win $200: Click here and use promo code GAMEDAYCBB.

Read Anthony Cervino’s hands-on BetMGM Sportsbook review to learn more.

🤔 Want a different BetMGM welcome offer? New users can instead get up to $1,000 risk-free with code GAMEDAY. 👇

BetMGM Sportsbook

BetMGM Sportsbook

  • Terrific Promotions

  • User-friendly Layout

  • Live Streaming

Get Up To $1,000 FREE

Risk-Free Bet

GAMEDAYGet bonus

New Customers Only, 21+. T&C’s Apply.


Duke vs. Michigan State Prediction

Duke, which ranked eighth in the country in points per game (80.1), has had defensive deficiencies of late. The Blue Devils surrendered an average of 67 points per game this season, yet has allowed more than that in five of their past seven, including five of the past six against Power 5 competition. 

The Spartans are 9-10 in their past 19 games, but Izzo always seems to pull out the stops this time of the year. Plus, the Spartans offense got off the mat in the second half against Davidson, outscoring the Wildcats 23-17 over the final 6:52 of regulation.

Still, Izzo has struggled throughout his career against legendary Duke coach Mike Krzyzewski, who is expected to retire at season’s end. Coach K owns a 12-3 record against the Spartans since Izzo took over in 1995, and 3-2 record in the tournament.

This will be the legendary coaches’ sixth head-to-head meeting, the most of any coaching duo in tournament history. Izzo claimed the most recent victory, a 68-67 result in the East Regional final in 2019.

Duke vs Michigan State Score Pick

Duke 72, Michigan State 71

Duke may have superior talent, but it’s been fickle of late, with just a 3-2 record over its past five that undoubtedly cost it a No. 1 seed. The Spartans were ranked as high as 10th in the nation in January, so this won’t be your typical 2 vs. 7 second-round affair.



When you factor in the exceptional coaching on both sides, this game should be nothing short of a classic.  

Duke vs. Michigan State Best Bets

Michigan State +6.5 (-110) at Caesars 

WAGER: 2 Units

The Spartans have been playing exceptionally close games. Each of their past five has been decided by 10 points or less, and four have been by six points or fewer.

Considering the comparable talent and coaching on each side, this should be a close game. Duke could pull away late, but Michigan State should be able to hang around.

spread

-110

Michigan St.: Cover +6.5 Spread vs Duke

Caesars Sportsbook Welcome OfferGet Up To $1,100 in Bet Insurance
Caesars Sportsbook Logo

Bet $20, Payout $38

UNDER 144.5 (-110) at Caesars

WAGER: 1 Unit

The Under is never a bad bet in a game featuring a team from the Big Ten, especially this time of year when the conference historically has been successful by grinding out games. Given Michigan State’s status as underdog, we’d also expect it to slow the game down in an effort to stay close to the Blue Devils.

If Michigan State is going to compete, which we expect it to, it can’t get in a track meet with Duke.

over-under

-110

Duke vs Michigan St.: UNDER 144.5 Points

Caesars Sportsbook Welcome OfferGet Up To $1,100 in Bet Insurance
Caesars Sportsbook Logo

Bet $20, Payout $38

Related articles

Promotions

Welcome offer Caesars Sportsbook promotion

Get Up To $1,100 in Bet Insurance

5 stars
Welcome offer BetMGM Sportsbook promotion

Get Up To $1,000 Risk-Free

5 stars
Welcome offer BetRivers Sportsbook promotion

Get Up To $250 Free 1st Deposit Match

5 stars
Welcome offer Betway Sportsbook promotion

Get Up To $1,000 Risk Free Bet

5 stars

Schedule & Odds

Top Offers

NBA Betting News