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NBA Predictions & Best Bets Today

Frank AmmiranteSenior Sports Writer
@FAmmiranteTFJ
Last Updated: Nov 5, 2025

We’ve got a jam-packed basketball slate for Wednesday, November 5, so it’s time to dive into my NBA predictions today.

On this page, you’ll find a best bet, over/under bet, and moneyline wager.

All NBA odds are current as of Friday, October 31st.

Frank Ammirante 2025-26 NBA Predictions Record: 10-5 (+5.32 units)

NBA Best Bets Today

Trail Blazers +3.5 (-102) vs Thunder

DraftKings Sportsbook • WAGER: 1 Unit

My NBA best bet today is the Trail Blazers +3.5 vs the Thunder.

This looks like a fishy line. Why is it so low against the defending champion Thunder, who have opened the season on an eight-game winning streak?

The reason is simple: this is the Thunder’s third game in the last four nights. We could see them rest a couple of key players in this spot.

On the other side, the Blazers are well-rested, having only played once since Halloween. This team has been scrappy so far, off to a respectable 4-3 start, so we’ll take them to cover the spread here.

Ride with the Blazers to keep it close in my NBA bet of the day.

76ers @ Cavaliers: Over 235.5 Points (-110)

DraftKings Sportsbook • WAGER: 1 Unit

I’ll add 76ers vs Cavaliers to go Over 235.5 points as my Over/Under wager for the night.

Bet on the Sixers playing at a faster pace with Joel Embiid (rest) out of the lineup. We’ve seen them pour on points at times this year, including 129+ in three games.

Cavs’ games have gone Under this number in six of seven this season, so why is it so high? It’s because the market is telling us that they project a fast-paced, high-scoring game here.

With that in mind, I’ll ride with the Over here.

Spurs ML (+114) at Lakers

DraftKings Sportsbook • WAGER: 1 Unit

The last pick of the day is the Spurs moneyline over the Lakers.

San Antonio is coming off their first loss of the season in a disappointing result at the Suns, but they’ve had two days of rest now, set to take on the Lakers, who are playing their third game in four nights.

The Lakers are coming off an impressive win at the Blazers, where they got it done without Luka Doncic and Austin Reaves.

Now back home, this sets up as a letdown against Victor Wembanyama and company.

NBA Best Betting Odds Today

Use our top NBA lines to place the best wagers throughout the NBA postseason:

Author

Frank Ammirante

Frank Ammirante is a Senior Sports Writer at The Game Day. Previously, he wrote for 4for4 Football and RotoBaller. Frank is a member of the Fantasy Sports Writer's Association while maintaining an active presence within the community. He has competed in industry contests like the Scott Fish Bowl, The Great Fantasy Baseball Invitational, and more. Frank will be making his debut in Tout Wars this year. He's got a diverse sporting background, but specializes in football and baseball.

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