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Best MLB Predictions Today

Frank AmmiranteSenior Sports Writer
@FAmmiranteTFJ
Last Updated: 18 hours ago

The 2026 MLB season is here, so keep this page bookmarked to find our best bets for baseball.

On this page, you’ll find our favorite moneyline, run line, and totals wagers. To read more of my plays, check out my X page @FAmmiranteTFJ.

The Game Day will have coverage for each game of the MLB season, including score predictions, best bets, and props. Be sure to check back daily for our MLB Play of the Day.

MLB Best Bets Today

MLB odds are courtesy of DraftKings Sportsbook as of June. 12

Tigers/Guardians F5 Under 4.5 Runs (-105)

WAGER: 1 unit • DraftKings Sportsbook

I’m going with the Under 4.5 runs in the first five innings between the Tigers and Guardians.

Jack Flaherty has been rolling lately, while Tanner Bibee owns the Tigers.

Look for a low-scoring start to this one.

MLB Best Bet Odds Today

Below are the latest odds for today’s MLB action.


How to Bet MLB Moneylines

Moneyline bets are a simple way of wagering on MLB games. All you need to do is pick the winner of the game, and you’ll win your bet.

The odds are pretty easy to understand, too. For example, if the Mets are a (-200) favorite, you would have to bet $20 to win $10. If they’re a (+200) underdog, you can win $20 off a $10 bet.

These odds will change every day depending upon the Mets’ matchup, so there’s always an opportunity for value every step of the way.

How to Bet MLB Run Lines

Run Line betting is another common way to bet on MLB games; you’re probably already familiar with it. You may know it as how much a team is “picked by" to win.

If the Red Sox are 1.5 run favorites over the Tigers, the Run Line would look something like this: Red Sox -1.5 (-200) vs Tigers +1.5 (+200).

In this scenario, the Red Sox would have to win by more than one run to cash your bet.

How to Bet MLB Over/Unders

If you’re unsure about a team’s moneyline or run line on a given day, you can still place a bet on the Over/Under — or total — in the matchup.

Sportsbooks will set a line for how many combined runs they project will be scored. From there, you can bet on the Over or Under.

For example, if you believe in the Braves’ offense and think it’ll be a high-scoring game, then you’ll want to take the Over. However, if it’s supposed to be more of a pitcher’s duel, you should go with the Under.

Author

Frank Ammirante

Frank Ammirante is a Contributor at The Game Day. You will also see his work at RotoBaller, FantasyPros, ProFootballNetwork, and much more. Frank is a member of the Fantasy Sports Writer's Association while maintaining an active presence within the community. He has competed in industry contests like the Tout Wars, Scott Fish Bowl, The Great Fantasy Baseball Invitational, and more. He's got a diverse sporting background, but specializes in football and baseball.

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