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Best MLB Predictions | Wednesday 9/28/22

Matt WilliamsDigital Content Coordinator
Posted: 12 hours agoLast updated: 12 hours ago

Happy Wednesday, everyone. We have a 15-game slate today, with just one afternoon contest, giving us plenty of options to choose from at our favorite sportsbooks.

That said, let’s dive right in and check out my favorite MLB best bet for today.

All MLB gameday odds are current as of Wednesday, Sept. 28, at 9 a.m. ET from the indicated sportsbook.

Matt Williams MLB Betting Record: 74-40, +40.2 Units

MLB Best Bet Today

Cleveland Guardians Moneyline (-124) at FanDuel Sportsbook

Cleveland Guardians vs Tampa Bay Rays

WAGER: 1 Unit

Tyler Glasnow will make his 2022 debut on Thursday after missing 14 months of recovering from Tommy John surgery. The right-hander posted a 2.66 ERA in 14 outings last season and could be a critical piece for the Tampa Bay Rays in the postseason.

That said, Glasnow will have a short leash of around 45 pitches during his return outing against the Cleveland Guardians, which should limit him to two or three innings of work.

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Cleveland will counter with 25-year-old Triston McKenzie, who boasts a 3.04 ERA and 0.96 WHIP over 180 ⅓ innings this season while sporting a 2.25 ERA over his previous 15 outings.

Glasnow was sharp during his rehab assignment, allowing one run on one hit over seven frames with 14 strikeouts. However, his limited workload, combined with the recent play of the Guardians, makes this our MLB bet of the day.

Catch more of our daily MLB bet picks


Matt Williams

Matt Williams is a Digital Content Coordinator with The Game Day, formerly of The Athletic and NBC Sports. Matt is the former host of the Turn Two Podcast and champion of both Tout Wars and the Kings Classic fantasy expert leagues. He has been nominated for an FSWA award and is known for his analytical breakdown threads on Twitter.

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