Patriots vs Colts Predictions Week 15 | NFL Pick of the Day

The 9-4 New England Patriots and 7-6 Indianapolis Colts were both off with a bye in Week 14, giving them extra time to prepare for this Saturday night’s AFC showdown in Indy.

While Mac Jones vs Carson Wentz doesn’t have the same panache as Tom Brady vs Peyton Manning, these two rivals are once again in the playoff hunt after reinventing themselves as power-run teams with great defenses.

Which one will prevail in Week 15? Let’s break down our Patriots vs Colts predictions and best bets.

Please note that all NFL Week 15 odds and lines are current as of 12 PM EST on Friday, December 17.

Patriots vs Colts Prediction

As mentioned, both teams should be well-rested and well-prepared for this critical matchup after last week’s bye.

The bye was especially well-timed for New England, who lost Damien Harris to a hamstring injury against the Buffalo Bills in Week 13. Harris will not return in time for this one, so Rhamondre Stevenson will lead the Patriots’ backfield once again. In the last game that Harris missed, Stevenson had 100 rushing yards and two touchdowns.


Sportsbook Play of the Day

Before reading our Patriots vs Colts tipster picks, you should know that Caesars Sportsbook is among the industry’s best, offering tons of promotions and a first-bet match (win or lose) up to $1,001 for new signups using our promo code GAMEDAY.

Read Chris Wassel’s Caesars Sportsbook review for more insight and get your welcome bonus below, or continue reading this analysis for our Patriots vs Colts betting tips.

Caesars Sportsbook

Caesars Sportsbook

  • Intuitive App

  • Plenty of Markets & Bet Types

  • VIP Rewards System

Get a FREE NBA Authentic Jersey

Bet $100, Get Free Jersey

Get Up To $1,001 Free Bet

First Bet Matched Win or Lose

GAMEDAYGet bonus

New Customers Only, 21+. T&C’s Apply.


Both teams were on fire prior to their byes, with Indy winning six of eight and New England winning seven straight. But will the time off halt their momentum?

While the Colts have the benefit of home-field advantage, they’re only 3-4 at home this year. Meanwhile, the Patriots are a perfect 6-0 on the road.

Look for New England to stay that way.

Prediction: Patriots 24, Colts 17

Jonathan Taylor Indianapolis Colts

Can Jonathan Taylor and the Indianapolis Colts beat the New England Patriots at their own game in NFL Week 15? (Image: USA TODAY Sports)


Patriots vs Colts Best Bets

Best Bet: Patriots Moneyline (+115) at Caesars

Wager: 1 Unit

The marquee matchup to watch in this game is Jonathan Taylor versus New England’s defense. With Derrick Henry sidelined, Taylor has taken over as the clear top running back in the NFL and launched himself into the MVP conversation.

Can the Pats slow down Taylor, who’s averaging over 100 rushing yards per game and leads the league with 18 non-passing touchdowns? New England’s been middle-of-the-pack in terms of rushing yards allowed but has ceded just six rushing touchdowns all season — the fewest in the NFL.

It’s no secret that Bill Belichick goes into games trying to shut down the opposing team’s best skill player. In this case, it’s unquestionably Taylor. If New England can hold him relatively in check and/or keep him out of the end zone for the first time since Week 3, they could reel off another victory.

Take the Pats at plus odds on our NFL gameday odds.

moneyline

+115

Patriots To Defeat Colts

NE @ IND | 12/19, 1:00 PM ET

Caesars Sportsbook Welcome OfferGet Up To $1,001 Free Bet + Free NBA Jersey
Caesars Sportsbook Logo

Bet $20, Payout $43

Best Bet: Under 45.5 Points (-110) at Caesars

Wager: 1 Unit

Both of these teams have good defenses. The Colts rank ninth with 21.8 points per game allowed, while the Pats are yielding the fewest points per game in the NFL at 15.4.

Part of the reason why these two defenses allow so few points is because their offenses control the game on the ground. Indy has the fifth-most rushing attempts in the league while New England ranks seventh.

With the expectation of a run-heavy game here in which the Patriots also prevent Taylor from scoring, I’ll roll with the Under for our NFL bet of the day.

over-under

-110

Patriots @ Colts: Under 45.5 Total Points

NE @ IND | 12/19, 1:00 PM ET

Caesars Sportsbook Welcome OfferGet Up To $1,001 Free Bet + Free NBA Jersey
Caesars Sportsbook Logo

Bet $20, Payout $38

Mike Barner’s season record: 16-24-1 (-10.34 units)

Thank you for reading our NFL Week 15 Patriots vs Colts Predictions! For more NFL betting tips, check out our NFL Week 15 Best Bets.

Related articles

Promotions

Welcome offer Caesars Sportsbook promotion

Get Up To $1,001 First Bet Match + Free NBA Jersey

5 stars
Welcome offer FOX Bet promotion

Get Up To $500 Risk-Free

5 stars
Welcome offer BetMGM Sportsbook promotion

Get Up To $1,000 Risk-Free

5 stars
Welcome offer Betway Sportsbook promotion

Get Up To $250 Risk-Free

5 stars

Schedule & Odds

Top Offers

NFL Betting News

  • Early money slightly leaning towards the over in the 49ers-Rams matchup

    DraftKings Sportsbook is reporting good two-way action on the over/under for the NFC Championship Game matchup between the San Francisco 49ers and Los Angeles Rams.

    Betting Impact:
    Per DraftKings, the over of 46 points has attracted 55% of the bets and 60% of the money thus far. Much moreso than the AFC Championship Game, the betting splits on the point spread and total in this game are much more evenly split, so the sportsbook does not have too much liability on either at the moment. From a moneyline perspective, Los Angeles's -170 moneyline odds have attracted 60% of the bets and 70% of the money.

    SF vs. LAR Game Page

  • Early bettors give slight lean to the Rams over the 49ers

    Based on the betting splits at DraftKings Sportsbook, the favored Los Angeles Rams are getting slightly more betting attention in their matchup with the San Francisco 49ers.

    Betting Impact:
    Per DraftKings, Los Angeles's -3.5 point spread has received 65% of the bets and 61% of the handle thus far. Bettors are clearly torn in this matchup considering the Rams have arguably been playing better football through the first two playoff games, while the 49ers have won six consecutive games against the Rams, including a thrilling Week 18 overtime victory in Los Angeles.

    SF vs. LAR Game Page

  • Early money more than 4/1 on the over in the Bengals-Chiefs matchup

    DraftKings Sportsbook is reporting one-sided betting action for Sunday's over/under in the matchup between the Cincinnati Bengals and Kansas City Chiefs.

    Betting Impact:
    Per DraftKings, the over of 54.5 points has attracted 75% of the bets and 85% of the money thus far. At this point, the sportsbook has big liability to the Chiefs point spread and the over in this matchup, as their most ideal scenario would be a Bengals cover in a low-scoring game at the moment. From a moneyline perspective, Kansas City's -335 moneyline odds have attracted 58% of the bets and 61% of the money.

    CIN vs. KC Game Page

  • Early money 3/1 on the Chiefs over the Bengals

    DraftKings Sportsbook is reporting one-sided betting action for Sunday's matchup between the Cincinnati Bengals and Kansas City Chiefs, as the majority of the action is backing the favored Chiefs.

    Betting Impact:
    Per DraftKings, Kansas City's -7 point spread has received 61% of the bets and 76% of the handle thus far. Cincinnati is shaping up to be the biggest need of any side or any total this weekend, as the public seems to be enamored with the Chiefs after their thrilling Divisional Round win over Buffalo.

    CIN vs. KC Game Page

  • 49ers-Rams over/under reaches lowest number of the week

    After another line movement, the over/under for the NFC Championship matchup between the San Francisco 49ers and Los Angeles Rams has reached its lowest total of the week.

    Betting Impact:
    Per DraftKings, the 49ers-Rams over/under on Sunday night was posted at 47.5 points. It was quickly bet down to 46.5 in less than 24 hours. However, it has once again moved toward the under, and now currently sits at 46 points. Given that there has not yet been buyback on the over, it is extremely unlikely we see the total get back to anywhere close to the 47.5 points it opened at.

    SF vs. LAR Game Page