49ers vs Cowboys Predictions | NFL Wild Card Playoffs Pick of the Day

The San Francisco 49ers will travel to AT&T Stadium to face off against the Dallas Cowboys in the Wild Card Round of the NFL Playoffs at 4:30 PM EST on Sunday.

The 49ers vs Cowboys is a rivalry for the ages, as these two stored franchises have battled in the postseason dating back to 1972. Now, they will meet again on Sunday afternoon in another win-or-go-home matchup.

Read on for our 49ers vs Cowboys predictions and best bets to get you primed for this crucial NFC clash.

All NFL Wild Card odds and lines are courtesy of Caesars Sportsbook and current as of 4:30 p.m. ET on Friday, January 14.

49ers vs Cowboys Prediction NFC Wild Card Playoffs

This game is poised to be a slugfest. While both clubs have potent offenses that ranked in the top three for yards per play, they also feature strong defenses that each ranked in the top 10 for fewest points allowed.

While Dallas finished first in scoring this year, their offense has been boom-or-bust. San Francisco, on the other hand, was more consistent but has a lower ceiling than the Cowboys’ explosive offense, which eclipsed 40 points five times this season.


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Given how evenly matched these teams are, the difference in this game will likely come down to ball security.

The Cowboys’ defense ranked No. 1 in takeaways (34) this season, while the 49ers ranked 21st in giveaways (24). Dallas’ (+14) turnover differential was also tops in the league, while San Francisco’s (-4) was 10th-worst.

If Dak Prescott can get his offense going, the Cowboys will be hard to stop. While the 49ers’ defense has played well, we have also seen them get gashed through the air. It will still be important for Dallas to establish the run, however, to keep San Francisco’s defense honest.

For the 49ers, it comes down to Jimmy Garoppolo. Garoppolo isn’t the most talented or mobile quarterback in the world. If the Cowboys’ fierce pass rush gets in his face all day, Garoppolo will struggle with his accuracy and make costly mistakes.

I have more trust in the Dallas defense than I do in their offense right now, but defense wins football games in the postseason, especially if it helps the Cowboys win the all-important turnover battle.

Prediction: Cowboys 30, 49ers 24

Jimmy Garoppolo San Francisco 49ers QB

Can Jimmy Garoppolo lead the San Francisco 49ers to a road win over the Dallas Cowboys during the 1st round of the NFL Playoffs? (Image: USA TODAY Sports)


49ers vs Cowboys Best Bets

*Anthony Cervino is 33-25 on his NFL Best Bets for 2021 for The Game Day.

Best Bet: Cowboys Moneyline (-160) at Caesars

Wager: 2 Units

This will be a close game and San Francisco will stay in it. However, I do expect Dallas to come out victorious in the end for our NFL bet of the day.

The Cowboys’ defense will be too much for Garoppolo to handle, and he’ll likely turn the ball over at least once as a result. Mistakes like that will end up costing the Niners the game.

Look for big performances on the defensive end from Micah Parsons and Trevon Diggs. They carried Dallas to the playoffs and will shine when it matters most.

Also of note:

  • The Cowboys are 5-1 in their last six meetings with the 49ers, including a 41-33 victory last season sans Dak Prescott at home.
  • The 49ers are 7-2 straight up in their past nine games and 4-1 over their past five, including two straight.
  • The Cowboys are 5-1 in their last six games.

moneyline

-160

Cowboys Defeat 49ers

SF @ DAL | 01/16, 4:30 PM ET

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Check out more of our 49ers vs Cowboys Predictions


Best Bet: Over 51 Total Points (-110) at Caesars

Wager: 1 Unit

This game can really go either way with the total on our NFL gameday odds. With my projected 30-24 final score, however, I’m betting on the Over.

While the betting trends suggest this game will go Under, I’m fading the trend. Both teams feature high-powered offenses, and the Cowboys in particular are capable of scoring off turnovers. Accordingly, we should see plenty of points on the scoreboard in this one.

Also of note:

  • The Over is 2-4 in the Cowboys’ past six games.
  • The Over is 1-4 in the 49ers’ past five games.
  • The Over is 4-2 in the past six meetings between the 49ers and Cowboys, hitting in two straight.

over-under

-110

49ers @ Cowboys: OVER 51 Points

SF @ DAL | 01/16, 4:30 PM ET

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Best Bet: Cowboys -3 (-115) at Caesars

Wager: 2 Units

Vegas seems to be favoring the 49ers on the road here. However, I am sticking to my guns and rolling with the Cowboys to cover again. Dallas was a league-best 13-4 against the spread this season, so expect that trend to continue on Sunday.

Looking at it another way, Dallas won 12 games this season, 11 of which were by at least four points.

If the Cowboys win, expect them to do so by at least a field goal.

spread

-115

Cowboys Cover -3 Spread vs 49ers

SF @ DAL | 01/16, 4:30 PM ET

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NFL Betting News

  • Early money slightly leaning towards the over in the 49ers-Rams matchup

    DraftKings Sportsbook is reporting good two-way action on the over/under for the NFC Championship Game matchup between the San Francisco 49ers and Los Angeles Rams.

    Betting Impact:
    Per DraftKings, the over of 46 points has attracted 55% of the bets and 60% of the money thus far. Much moreso than the AFC Championship Game, the betting splits on the point spread and total in this game are much more evenly split, so the sportsbook does not have too much liability on either at the moment. From a moneyline perspective, Los Angeles's -170 moneyline odds have attracted 60% of the bets and 70% of the money.

    SF vs. LAR Game Page

  • Early bettors give slight lean to the Rams over the 49ers

    Based on the betting splits at DraftKings Sportsbook, the favored Los Angeles Rams are getting slightly more betting attention in their matchup with the San Francisco 49ers.

    Betting Impact:
    Per DraftKings, Los Angeles's -3.5 point spread has received 65% of the bets and 61% of the handle thus far. Bettors are clearly torn in this matchup considering the Rams have arguably been playing better football through the first two playoff games, while the 49ers have won six consecutive games against the Rams, including a thrilling Week 18 overtime victory in Los Angeles.

    SF vs. LAR Game Page

  • Early money more than 4/1 on the over in the Bengals-Chiefs matchup

    DraftKings Sportsbook is reporting one-sided betting action for Sunday's over/under in the matchup between the Cincinnati Bengals and Kansas City Chiefs.

    Betting Impact:
    Per DraftKings, the over of 54.5 points has attracted 75% of the bets and 85% of the money thus far. At this point, the sportsbook has big liability to the Chiefs point spread and the over in this matchup, as their most ideal scenario would be a Bengals cover in a low-scoring game at the moment. From a moneyline perspective, Kansas City's -335 moneyline odds have attracted 58% of the bets and 61% of the money.

    CIN vs. KC Game Page

  • Early money 3/1 on the Chiefs over the Bengals

    DraftKings Sportsbook is reporting one-sided betting action for Sunday's matchup between the Cincinnati Bengals and Kansas City Chiefs, as the majority of the action is backing the favored Chiefs.

    Betting Impact:
    Per DraftKings, Kansas City's -7 point spread has received 61% of the bets and 76% of the handle thus far. Cincinnati is shaping up to be the biggest need of any side or any total this weekend, as the public seems to be enamored with the Chiefs after their thrilling Divisional Round win over Buffalo.

    CIN vs. KC Game Page

  • 49ers-Rams over/under reaches lowest number of the week

    After another line movement, the over/under for the NFC Championship matchup between the San Francisco 49ers and Los Angeles Rams has reached its lowest total of the week.

    Betting Impact:
    Per DraftKings, the 49ers-Rams over/under on Sunday night was posted at 47.5 points. It was quickly bet down to 46.5 in less than 24 hours. However, it has once again moved toward the under, and now currently sits at 46 points. Given that there has not yet been buyback on the over, it is extremely unlikely we see the total get back to anywhere close to the 47.5 points it opened at.

    SF vs. LAR Game Page