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2021 NFL Early Lines Week 6 | Opening Betting Odds & Implied Totals for NFL Games This Week

Posted: Oct 11, 2021Last updated: Oct 11, 2021

Checking NFL early lines each week gives prospective football bettors a solid idea of trends that the sportsbooks and the public will enact for that week’s action.

To offer our NFL readers perspective, we’ve gathered some Week 6 NFL Opening Lines and Odds, including moneyline, against the spread, Over/Under, and implied total information to start your betting off right.

2021 NFL Early Lines Week 6: Opening Odds & Betting Info for NFL Games This Week

  • All Week 6 NFL gameday odds and lines are from Caesars Sportsbook.
  • Week 6 NFL lines data is current as of 8 p.m. ET on Sunday, October 10.
  • NFL Week 6 Teams on Bye: Atlanta Falcons, New Orleans Saints, New York Jets, San Francisco 49ers

Tampa Bay Buccaneers @Philadelphia Eagles (Thursday Night Football, 8:20 p.m. ET)

  • Moneyline: Buccaneers (-110), Eagles (+260)
  • Spread: Buccaneers -6.5 (-110), Eagles +6.5 (-110)
  • Over/Under Points Total: Over 52.5 (-110), Under 52.5 (-110)
  • Implied Score: Buccaneers 29.5, Eagles 23

Tom Brady’s 4-1 Buccaneers host the Philadelphia Eagles, both clubs fresh off wins. Can Jalen Hurts hang with the GOAT’s defending Super Bowl champions?


Sportsbook Play of the Day

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Read Chris Wassel’s Caesars Sportsbook review for more insight and get your welcome bonus below before reading the rest of the NFL Week 6 Early Lines.


Miami Dolphins @ Jacksonville Jaguars (9:30 a.m. ET, London)

  • Moneyline: Dolphins (-110), Jaguars (+155)
  • Spread: Dolphins -3 (-115), Jaguars +3 (+105)
  • Over/Under Points Total: Over 44 (-110), Under 44 (-110)
  • Implied Score: Dolphins 23.5, Jaguars 20.5

The second back-to-back and final NFL London game pits the two other Florida squads against each other.

Los Angeles Rams @ New York Guants (1 p.m. ET)

  • Moneyline: Rams (-115), Giants (-105)
  • Spread: Rams -7 (-110), Giants +7 (-110)
  • Over/Under Points Total: Over 49 (-110), Under 49 (-110)
  • Implied Score: Rams 28, Giants 21

Minnesota Vikings @ Carolina Panthers (1 p.m. ET)

  • Moneyline: Vikings (+100), Panthers (-120)
  • Spread: Vikings +1 (-110), Panthers -1 (-110)
  • Over/Under Points Total: Over 47 (-110), Under 47 (-110)
  • Implied Score: Panthers 24, Vikings 23

Los Angeles Chargers @ Baltimore Ravens (1 p.m. ET)

  • Moneyline: Chargers (-110), Ravens (-110)
  • Spread: Chargers +3 (+100), Ravens -3 (-120)
  • Over/Under Points Total: Over 48 (-110), Under 48 (-110)
  • Implied Score: Ravens 25.5, Chargers 22.5

Sure, these two defenses have some talent, but the Chargers just let an injured Baker Mayfield‘s Cleveland Browns drop 42 points on them. With Justin Herbert and Lamar Jackson under center, these two clubs should pile up points — especially if the Ravens can activate talented rookie wide receiver Rashod Bateman (groin) from injured reserve.

Hammer the Over while the total is so low.

Green Bay Packers at Chicago Bears (1 p.m. ET)

  • Moneyline: Packers (-180), Bears (+155)
  • Spread: Packers -4.5 (-110), Bears +4.5 (-110)
  • Over/Under Points Total: Over 46 (-110), Under 46 (-110)
  • Implied Score: Packers 25.25, Bears 20.75

Cincinnati Bengals @ Detroit Lions (1 p.m. ET)

  • Moneyline: Bengals (-110), Lions (-110)
  • Spread: Bengals -3.5 (-110), Lions +3.5 (-110)
  • Over/Under Points Total: Over 49 (-110), Under 49 (-110)
  • Implied Score: Bengals 26.25, Lions 22.75

Houston Texans @ Indianapolis Colts (1 p.m. ET)

  • Moneyline: Texans (-105), Colts (-115)
  • Spread: Texans +7 (-110), Colts -7 (-110)
  • Over/Under Points Total: Over 49 (-110), Under 49 (-110)
  • Implied Score: Colts 28, Texans 21

Kansas City Chiefs @ Washington Football Team (1 p.m. ET)

  • Moneyline: Chiefs (-110), Washington (-110)
  • Spread: Chiefs -6 (-110), Washington +6 (-110)
  • Over/Under Points Total: Over 54 (-110), Under 54 (-110)
  • Implied Score: Chiefs 30, Washington 24

Arizona Cardinals @ Cleveland Browns (4 p.m. ET)

  • Moneyline: Cardinals (-110), Browns (-110)
  • Spread: Cardinals +3 (-110), Browns -3 (-110)
  • Over/Under Points Total: Over 52.5 (-110), Under 52.5 (-110)
  • Implied Score: Saints 22, Washington 22

Las Vegas Raiders @ Denver Broncos (4:25 p.m. ET)

  • Moneyline: Raiders (-110), Broncos (-110)
  • Spread: Raiders +2.5 (-110), Broncos -2.5 (-110)
    Over/Under Points Total: Over 44 (-110), Under 44 (-110)
  • Implied Score: Broncos 23.25, Raiders 20.75

Dallas Cowboys @ New England Patriots (4:25 p.m. ET)

  • Moneyline: Cowboys (-110), Patriots (-110)
  • Spread: Cowboys -1 (-110), Patriots -1 (-110)
    Over/Under Points Total: Over 48 (-110), Under 48 (-110)
  • Implied Score: Cowboys 24.5, Patriots 23.5

Seattle Seahawks at Pittsburgh Steelers (Sunday Night Football, 8:20 p.m. ET)

  • Moneyline: Seahawks (-110), Steelers (-110)
  • Spread: Seahawks -1 (-110), Steelers +1 (-110)
  • Over/Under Points Total: Over 48 (-110), Under 48 (-110)
  • Implied Score: Seahawks 24.5, Steelers 23.5

Buffalo Bills at Tennessee Titans (Monday Night Football, 8:15 p.m. ET)

  • Moneyline: Bills (-110), Titans (-110)
  • Spread: Bills -3 (-120), Titans +3 (+100)
  • Over/Under Points Total: Over 53.5 (-110), Under 53.5 (-110)
  • Implied Score: Bills 28.25, Titans 25.25

Thanks for reading our NFL Week 6 Early Lines!

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