NFL Week 4 Parlays Picks & Predictions – NFL Play of the Day

We’re off to a brutal start with parlay betting, as it was another week without a win. I expected a better performance from some of the underdogs, particularly the Chicago Bears with Justin Fields making his debut.

It’s time to buckle down and get back on track here in Week 4. This is going to be a huge week, I can already feel it!

Let’s take a deeper dive to see which are my favorite parlay bets for Week 4 in the NFL play of the day series!

Please note that all odds are current as of Monday, September 27.

Best NFL Parlays Week 4

NFL Week 4 Parlay Picks

  • Houston Texans +17 (-110) Spread at Caesars (at Buffalo Bills)
  • New York Jets +7.5 (-110) Spread at Caesars (vs Tennessee Titans)
  • New York Giants +8 (-110) Spread at Caesars (at New Orleans Saints)

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Houston Texans +17 (-110) Spread at Caesars (at Buffalo Bills)

The Houston Texans are massive 17-point underdogs, which looks like an overreaction to Week 3, where they struggled to move the ball with rookie quarterback Davis Mills and the Buffalo Bills blew out the Washington Football Team. Houston has been a scrappy team so far, and I like their chances at covering this huge number.

New York Jets +7.5 (-110) Spread at Caesars (vs Tennessee Titans)

The New York Jets have been outscored 51-6 in their last two games, but the Tennessee Titans have no business coming in as 7.5-point road favorites. Tennessee has squeaked out wins over the Seahawks and Colts after a blowout Week 1 home loss to the Cardinals.

Their defense is also exploitable, making this a potential get-right spot for the Jets. I’ll take the home dog here.

New York Giants +8 (-110) Spread at Caesars (at New Orleans Saints)

The final pick on our first parlay is the New York Giants at 8-point underdogs. The Giants have kept it close in each of their last two losses, losing by 1 and 3 points, respectively, which is reflected in the NFL gameday odds.

They head to New Orleans to take on an inconsistent Saints team that has blown out Green Bay and New England, but lost handily to the Panthers. I don’t think this team is good enough to be laying 8 points, which makes this one of our picks of the day.

prop bet

+596

Houston Texans +17; New York Jets +7.5; & New York Giants +8 (NFL Week 4)

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Zach Wilson, QB, New York Jets

Could Week 4 serve as a turning point for Zach Wilson and the New York Jets? (Image: USA TODAY Sports)


NFL Week 4 Longshot Parlay Prediction

  • Los Angeles Rams -6 (-110) Spread at Caesars (vs Arizona Cardinals)
  • New York Giants +8 (-110) Spread at Caesars (at New Orleans Saints)
  • New England Patriots +6.5 (-110) Spread at Caesars (vs Tampa Bay Buccaneers) 
  • Los Angeles Chargers -3.5 (-110) Spread at Caesars (vs Las Vegas Raiders) 
  • Baltimore Ravens +1 (-105) Spread at Caesars (at Denver Broncos)

Los Angeles Rams -6 (-110) Spread at Caesars (vs Arizona Cardinals)

The Los Angeles Rams are firing on all cylinders with new quarterback Matthew Stafford, so I can’t pass them up here. I don’t think the Cardinals have enough on defense to slow down this prolific offense.

New York Giants +8 (-110) Spread at Caesars (at New Orleans Saints)

I’ll add the Giants as well, because they’re my favorite play on the previous parlay.

New England Patriots +6.5 (-110) Spread at Caesars (vs Tampa Bay Buccaneers)

The New England Patriots are coming off a poor showing in their loss to the New Orleans Saints, but now head coach Bill Belichick gets to square off with Tom Brady. I have to think the Pats will be highly motivated here, which should be enough to cover the 6.5-point spread as home underdogs.

Los Angeles Chargers -3.5 (-110) Spread at Caesars (vs Las Vegas Raiders)

The Los Angeles Chargers are coming off a huge road upset win over the Kansas City Chiefs. Their defense has been great under new head coach Brandon Staley, while Justin Herbert continues to establish himself as a star at quarterback.

The Las Vegas Raiders are off to a good start, but I don’t think they’re as good as their record. Give me the Chargers at this low spread.

Baltimore Ravens +1 (-105) Spread at Caesars (at Denver Broncos)

The Baltimore Ravens are only 1-point road underdogs to the undefeated Denver Broncos. It’s clear that the Ravens are viewed as the better team in this spot.

The Broncos have beaten up on the Giants, Jaguars, and Jets so far. These teams have a combined record of 0-9. Give me the Ravens plus the points.

prop bet

+2493

Los Angeles Rams -6; New York Giants +8; New England Patriots +6.5; Los Angeles Chargers -3.5; & Baltimore Ravens +1 (NFL Week 4)

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Same Game Parlay Picks Week 4

  • Los Angeles Chargers -3.5 (-110) Spread at Caesars (vs Las Vegas Raiders)
  • Raiders/Chargers UNDER 52.5 (-110) Total at Caesars

The Los Angeles Chargers have held the Dallas Cowboys to 20 points and the Kansas City Chiefs to 24 points in the last two weeks. That’s highly impressive, considering that these are two of the most explosive offenses in the NFL.

The Las Vegas Raiders have surprisingly jumped out to a 3-0 start, with quarterback Derek Carr looking like a potential MVP candidate, but I refuse to believe in this team right now. They’re definitely better than I expected, but they still look like an average team on paper.

The Chargers just limited Patrick Mahomes to only 5.9 yards per attempt along with 2 interceptions. I think they’ll make Carr crash back down to Earth in this spot. I also believe that the 3.5 points are putting too much stock in the Raiders’ surprising start.

The Chargers are simply the much better team here, which is a big reason why this is our NFL bet of the day.

I like rolling with the Under because of how good this Chargers defense is, as their games have totaled 36, 37, and 54 points so far this season. The 52.5-point total is simply too high given Los Angeles’ combination of strong talent and coaching on defense.

prop bet

+264

Los Angeles Chargers -3.5 & Point Total Under 52.5 (LV @ LAC, NFL Week 4)

LV @ LAC | 10/04, 8:15 PM ET

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Thanks for reading our NFL Week 4 Parlays Picks & Predictions! For more NFL Week 4 betting tips, check out our NFL Week 4 Best Bets

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