NFL Prop Bets Week 1 | Player Props & Game Prop Betting Tips

Posted: Sep 10, 2022Last updated: Jan 23, 2023

Every week, we provide our featured and favorite game and player NFL prop bets. We cover it all, from daring wagers to more apparent strong plays. There is a varied style of bets to consider with a heavy emphasis on diversifying our targeted games.

There’s something for everyone here on a jam-packed Week 1 NFL schedule. We consider game flow, matchups, injuries, and many other key factors before finalizing our suggestions.

Week 1 NFL Prop Bets

Buccaneers vs Cowboys: Bucs Cover -1 1Q Spread (+125) at DraftKings Sportsbook

WAGER: 2 Units

The Cowboys’ offense does not match up well with the ferocious Tampa Bay defense. Dak Prescott’s arsenal of pass-catchers looks less impressive this season, and rushing yards may be hard to come by against the Buccaneers’ stout front seven.

Meanwhile, an inconsistent Dallas pass defense will pay for any mistakes against Tom Brady as he quickly pilots the Buccaneers to a comfortable first-quarter lead.

Ravens vs Jets: 1st Scoring Play Ravens TD (+120) at DraftKings

WAGER: 1.5 Units

The Ravens’ defense is looking healthier and formidable again, and the Jets’ offense needs time to gel even though the talent is promising for eventual success. Baltimore will cut significant holes in the Jets’ front seven while engineering a tone-setting early scoring drive as the Ravens revert to a comfortable run-heavy approach.

Mike Davis may prove to be surprisingly effective as a lead RB.

49ers vs Bears: 49ers Win 1H by 13+ Points (+425) at DraftKings

WAGER: 1 Unit

San Francisco has decisive matchup edges on both sides of the ball. Their offensive playmakers can do a lot of the work after the catch for Trey Lance against the Chicago pass defense.

  • Check out the latest NFL Week 1 Odds for more on the upcoming slate of games.

The 49ers’ front seven is going to make it a long day for Justin Fields, who does not have enough weaponry to challenge the San Francisco secondary. The Niners are going to be up comfortably at halftime.

Saints vs Falcons: Saints Win Both Halves (+180) at DraftKings

WAGER: 1 Unit

The Saints’ defense is one of the best in the league, and the Falcons don’t have the quarterback or playmakers needed to put up much of a battle. On the other side of the ball, Jameis Winston has a lot of weaponry to work with against a Falcons defense that has not improved much.

Once Atlanta gets behind, the New Orleans defense will feast. You should also consider the Saints’ defense/special teams to score a TD at (+450).

Patriots vs Dolphins: Patriots Score 1st And Lose (+285) at DraftKings

WAGER: 1 Unit

The Patriots do have a sturdy running game, so they could at least muster a field goal on an early drive. But ultimately, New England figures to fall far behind against Miami.

The Dolphins have won three of the last four against the Patriots, and their secondary and pass rush will make it very difficult on Mac Jones and his mediocre receiving crew.

Miami also has too much talent on offense this season for New England to handle. The Patriots will have their hands full in the secondary with Tyreek Hill, Jaylen Waddle, Ced Wilson, and Mike Gesicki.

Packers vs Vikings: Vikings Win 1st Half By 4-6 Points (+800) at DraftKings

WAGER: 0.5 Units

This will be a close game, and maybe it won’t be a very high-scoring affair. The Minnesota offense should be more potent this year, but Green Bay has a solid defense. The Packers also have uncertainty among the wide receiving crew.

The Vikings have more proven playmakers and enough to help them notch a slight edge at the half.

Week 1 NFL Player Props

Alec Pierce: Anytime TD vs Texans (+210) at DraftKings

WAGER: 2 Units

The Houston secondary is again one of the worst in the league, and the Colts will come out looking to feature a more balanced offensive attack guided by Matt Ryan. He is no longer an elite passer, but Ryan can still effectively lead an offense.

Pierce, an impressive second-round pick, should be his top target other than Michael Pittman Jr. in Indy’s season-opener.

Pierce is coming off a strong preseason and will get some targets near the goal line. He is a big receiver who can be a matchup problem for the Houston defensive backs.

Amari Cooper: UNDER 50.5 Receiving Yards vs Panthers (-120) at DraftKings

WAGER: 2 Units

Cleveland is going to struggle in the passing game until Deshaun Watson returns, and Cooper takes a big hit in the quarterback department working with Jacoby Brissett. Carolina has a good secondary and can shut Cooper down without having to worry much about his complements in the receiving game.

Browns-Panthers figures to be a lower-scoring affair, and Cleveland likely won’t be able to pad any passing numbers while playing from behind.

Jalen Hurts: OVER 229.5 Passing Yards vs Lions (-115) at DraftKings

WAGER: 2.5 Units

Hurts went over this number just five times last season, and only twice after his fourth game, so this would appear to be no slam dunk based on what we saw statistically in 2021.

However, with the addition of A.J. Brown, Hurts has the needed pass-catchers to improve his production. The Detroit defense still looks highly vulnerable, and Hurts will be aiming to demonstrate that he is making strides forward as a pure passer.

Rashaad Penny: 1st TD Scorer vs Broncos (+1100) at DraftKings

WAGER: 1 Unit

The Broncos intend to let Russell Wilson rip against the Seahawks secondary in his first game as a visitor to Lumen Field. Seattle must counter with its running game to control time of possession and keep Wilson on the sidelines as much as possible.

In an emotional matchup, Pete Carroll will strike first with his top RB.

Antonio Gibson: 1st TD Scorer vs Jaguars (+625) at DraftKings

WAGER: 1 Unit

Gibson is coming off a forgettable preseason but is now ticketed to be Washington’s lead running back again. He must get off to a good start to show he is still deserving of a significant workload.

Washington must exhibit a solid running game to support Carson Wentz, and the Commanders can put together a good early drive against a suspect Jacksonville front seven.

Scoring first will make a statement for both the running back and the Washington offense to begin the season. The optimism may not linger for much of the year, but the Commanders can establish that they will stay in the game in the season opener.

Gibson has rushed for 18 TDs in the past two years, so this scenario certainly is not far-fetched.

Mecole Hardman: Anytime TD vs Cardinals (+260) at DraftKings

WAGER: 1.5 units

The Chiefs begin the post-Tyreek Hill era needing to establish other deep threats. Former Packer Marquez Valdes-Scantling is one option, but Hardman does have a more established on-field rapport with Patrick Mahomes.

The Arizona secondary is looking very depleted and shaky heading into the season opener, and Hardman is a viable option to catch a rainbow from Mahomes and zip into the end zone.

Davante Adams: OVER 78.5 Receiving Yards vs Chargers (-115) at DraftKings

WAGER: 3 Units

This appears to be one of the strongest plays of the week. The Chargers are going to be without J.C. Jackson as he continues to recover from ankle surgery. Adams will chew up yardage as he reunites with former Fresno State teammate Derek Carr in their first game as NFL teammates.

Adams should be the star of what may turn out to be a high-scoring contest between the Raiders and Chargers.


Scott Engel

Scott Engel is a Senior Sports Writer at The Game Day. Previously he was at and The Athletic. His work is also featured at RotoBaller and on Scott is a host on SiriusXM Fantasy Sports Radio. He is an inaugural member of the Fantasy Sports Writers Association's Hall of Fame. Scott is a four-time FSWA award winner and a 13-time finalist. He was an Associate Editor and featured writer at and his career began at CBS SportsLine, where he was a Senior Writer and Managing Editor. Scott was the Managing Director at RotoExperts.

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