All odds

Rams vs Cardinals Predictions

Lance PattonPromotions Creator & Editor
Posted: Sep 20, 2022Last updated: 2 days ago

The Los Angeles Rams will play their first divisional game of the season when they go on the road to State Farm Stadium to take on the Arizona Cardinals.

The Cardinals trailed 20-0 to the Raiders at halftime in Week 2, but battled back behind two fourth-quarter touchdowns and two 2-point conversions to win in overtime. It was a much-needed comeback to get to 1-1 on the season.

The Rams held on to beat the Falcons 31-27, and the defending Super Bowl Champions are back on track after a loss to the Bills in Week 1.

Continue reading for the odds and our Los Angeles at Arizona best bets and predictions.

Rams vs Cardinals Odds

The Cardinals opened as a four-point home underdog, and it has stayed above the traditional football number of three points, a surprise with home field in a divisional contest.

The total opened at 50.5, one of the higher totals in Week 3 on Caesars, but dropped two points and dipped below the key number of 49.

Take a look at the best Rams odds and Cardinals odds for the 2022 NFL season.

Rams vs Cardinals Implied Totals

Rams 26, Cardinals 22.5

The Rams are expected to go on the road and get the win in a high-scoring game. The Cardinals haven’t received much respect from bookmakers this season, being an underdog in each of their first three games.

Rams vs Cardinals Pick of the Day

Read more on this Rams vs Cardinals bet below.

Rams vs Cardinals Prediction

Rams 28, Cardinals 27

It’s the first divisional game of the season for these NFC West foes, and the winner will have a considerable leg up early in the season.

Matthew Stafford and the Rams’ offense have struggled early this season. Stafford has 512 yards and four touchdowns but has thrown five interceptions which is the most in the league. The run game, led by Darrell Henderson Jr., has been non-existent, averaging 58.5 yards per game this season.

The good news for the Rams? They have Cooper Kupp.

Kupp is coming off the best wide receiver season in NFL history and has picked up right where he left off, catching 24 passes for 236 yards and three touchdowns through two games.

The Cardinals’ defense has been one of the worst units in the NFL through their opening two games. They’ve allowed 6.4 yards per play and 302 passing yards per game, ranking 29th and 31st in the NFL respectively.

Kyler Murray deserves a ton of credit for the comeback win over the Raiders. His ability to extend plays with his legs ignited the offense, running in a two-point conversion and then eventually the game-tying touchdown.

The PED suspension for DeAndre Hopkins has undoubtedly been a factor in the Cardinals’ passing attack. The newly acquired Marquise Brown (13 catches, 111 yards, 1 TD) and second-year speedster Greg Dortch (11 receptions, 118 yards, 1 TD) lead the team in receiving through two games.

Rams vs Cardinals Bet Tips

The Rams have had the Cardinals’ number over the last couple of seasons.

  • The Rams are 9-1-1 against the spread and 10-1 straight up in their last 11 meetings against Arizona.
  • The Rams have covered seven straight games when playing on the road against Arizona.
  • The Cardinals have generally been able to put points on the board against the Rams, and the total has gone Over in four of the last six meetings.

Rams vs Cardinals Best Bets

Cardinals +3.5 (-110) at Caesars Sportsbook

Los Angeles has shown glimpses of the dreaded Super Bowl hangover and the defense has shown signs of aging, especially in the second half of their Week 2 win over the Falcons. The run game has faltered, they’re lacking a second option at wide receiver, and they’ve had too many turnovers.

Not a great combination to be heading on the road for their first divisional game of the season.

Arizona will be able to overcome their recent history of struggling against the Rams, and will be in this game until the end behind an electrifying performance from Kyler Murray.

Before placing this bet, get the best Cardinals promo codes.

Under 48.5 Total Points (-110) at Caesars

The Rams are one-dimensional on the offensive end this season, and Cardinals DC Vance Joseph was able to keep Cooper Kupp under wraps in the NFC Wild Card last season.

The familiarity of a division game leads to a couple of turnovers and a low-scoring, grind-it-out affair where the total stays Under.

Before placing this bet, get the best Rams promo codes.


Lance Patton

Related articles