The Buffalo Bills and Denver Broncos will meet on Saturday in an intriguing AFC Divisional Round game that could go either way.
At first glance, this looks like a potential low-scoring affair due to Denver’s stout defense, but we’ve seen the Broncos get into some shootouts at home at times. This includes games against the Jaguars and Packers.
With that in mind, there are sure to be some good spots for Bills vs Broncos props, so let’s dive further into this AFC Divisional Round matchup.
All NFL odds used for these Bills vs Broncos player props are current as of Wednesday, Jan. 14, and courtesy of DraftKings Sportsbook.
Best Bills vs Broncos Player Props
Josh Allen: Under 36.5 Rushing Yards (-109) @ Broncos
Allen is dealing with foot, finger, and knee injuries right now. Since he’s banged up, he’s unlikely to run at the same rate as usual. We saw that against the Jaguars.
Even though Allen had 11 carries, they only went for 33 yards because several of them were on tush pushes. Watching that game, Allen was sitting in the pocket and getting rid of the ball quickly.
Allen has gone under this number in three consecutive games, so I’m betting on this trend continuing against the Broncos as my NFL pick of the day.
Bo Nix: Under 20.5 Completions (-105) vs Bills
The Bills have one of the best pass defenses in the NFL, so I’m taking Broncos quarterback Bo Nix to complete fewer than 20.5 passes.
Not only does this Buffalo group limit big plays downfield, but it also makes it difficult for opposing quarterbacks to complete passes. During the season, the Bills allowed the fewest completions in the NFL, averaging just over 16 per game.
- Get ready for this matchup with our Bills vs Broncos predictions.
Opposing offenses have also enjoyed plenty of success rushing against the Buffalo defense, which allows over five yards per carry, so there isn’t a need to rely on the passing attack.
We just saw Trevor Lawrence complete only 18 passes against this group in the Wild Card Round, so I’ll fade Nix as well.
Khalil Shakir: Over 5.5 Receptions (-110) @ Broncos
Shakir got peppered with targets against the Jaguars, hauling in 12 receptions for 82 yards.
As a slot receiver who is often targeted in the short-to-intermediate passing game, it’s always a better idea to target receptions instead of yards for Shakir.
- Sign up for The Game Day Newsletter to get the latest bet tips and sportsbook promos.
With so many injuries at wide receiver, combined with Allen running at a lower rate, look for the star quarterback to continue to get rid of the ball quickly, targeting Shakir early and often.
Consider this wager with the top sportsbook promotions for 2026.
Evan Engram: Under 2.5 Receptions (-119) vs Bills
Engram has had a disappointing season for the Broncos, putting up only 50 catches for 461 yards and one touchdown.
This matchup looks like a great spot to fade him, as the Bills allowed the fewest receptions to tight ends this season. In fact, it wasn’t close, as Buffalo gave up only 46 catches, while the team allowing the second-fewest was the Eagles at 67.
We saw just Brenton Strange catch only two passes against the Bills on Sunday, so I’ll go with the under on Engram to round out my Bills vs Broncos Divisional Round props.
