NFL Prop Bets Week 2

Last Updated: Sep 16, 2022

Every week, we provide our featured and favorite game and player NFL prop bets. We cover it all, from daring wagers to more apparent strong plays. You will enjoy the varied styles of bets to consider with a heavy emphasis on diversifying our games targeted.

There’s something for everyone here on the Week 2 NFL schedule. We consider game flow, matchups, potential rebound performances, and many other key factors before finalizing our suggestions.

Week 2 NFL Prop Bets

Buccaneers vs Saints: First Score, TB Field Goal (+360) at DraftKings Sportsbook

WAGER: 1 Unit

The Saints’ defense allowed the Falcons to score 16 first-half points last week and they are obviously facing a much better offense in Week 2. But Mike Evans has endured some tough outings vs Marshon Lattimore, and the Buccaneers are dealing with some notable injuries on offense.

Still, Tom Brady can move the ball effectively enough to put Ryan Succop in range early after he made four field goals against Dallas in the opener.

The Saints had 10 points in the first three quarters last week, and it does not look good for Jameis Winston to score first against the stout Tampa Bay defense. The Buccaneers should be able to get on the board first with the obvious advantage at QB.

New York Jets vs Browns: CLE Over 10.5 2H Points (+105) at DraftKings

WAGER: 1.5 Units

With Jacoby Brissett at QB, it is very apparent that Cleveland will continue to lean heavily on their ground game. The Jets have dink and dunker Joe Flacco at QB and are unlikely to be in a position to force the Browns to play catch-up in the second half.

Cleveland allowed 261 total yards in Week 1 and will greatly limit the Jets’ offense while using Nick Chubb and Kareem Hunt to extend their lead.

  • Check out the latest NFL Week 2 Odds for more on the upcoming slate of games.

The Browns rushed for 217 yards against the Panthers last week, and the Jets won’t be able to stop the Cleveland ground game even though it’s obvious what the Browns plan to do on offense. Cleveland will wear the New York defense down while adding to its edge later in the game.

Falcons vs Rams: LAR Win By 13-18 Points (+425) at DraftKings

WAGER: 1 Unit

You can expect an impressive rebound performance from the Rams’ offense after they were smoked by Buffalo last week. The Atlanta defense should continue to be one of the worst in the league this season, and Los Angeles may roll up a lot of points on their way to a rout in this one. Matthew Stafford will get Allen Robinson involved this week as both guys put a forgettable opener behind them.

The Rams will want to make a statement and get back on a clear winning path this week, and you can expect a victory total in double digits in their home opener.

Bengals vs Cowboys: CIN Wins Both Halves (+130) at DraftKings

WAGER: 2 Units

After a mistake-prone showing against the Steelers in Week 1, the Bengals will have a decisive matchup advantage over a Cowboys team missing its starting QB. Some NFL backups can perform respectably when called into action, but the Dallas offense doesn’t project to offer much punch with Cooper Rush.

He has only started one NFL game in his career, and he didn’t offer any signs of encouragement in the preseason, with no TD passes in three games.

Dallas can be aggressive on defense, but that will lead to a few big plays surrendered even if the Bengals keep turning the ball over. The Cowboys didn’t score a touchdown against Tampa Bay, and their offense won’t deliver much this week, either. The Bengals should easily maintain a significant edge on the scoreboard throughout the day.

Texans vs Broncos: DEN Wins 1st Half By 4-6 Points (+650) at DraftKings

WAGER: 1 Unit

Denver will certainly perform better on offense after a disappointing outing at Seattle, but the Texans should stick close for a while. Houston will be generous on defense, but Davis Mills can keep his team in the game. He does not make many mistakes, and Houston was able to tie Indianapolis last week in a matchup some expected to be more one-sided in the Colts’ favor.

The Broncos will certainly win this game, but the Texans will hang tough for at least one half. If Houston can get the running game moving effectively behind rookie Dameon Pierce, then Denver’s halftime margin can stay below a touchdown. Pinpointing an exact window of the lead is a fun way to cash in as you watch the time tick away in the first half.

Titans vs Bills: BUF 1H -5.5/Over 24.5 Total Points (+235) at DraftKings

WAGER: 1.5 Units

After decisively dispatching the defending Super Bowl champions on the road, Buffalo is going to pull away quickly from an overmatched opponent at home. Tennessee allowed 394 yards of offense to the Giants in Week 1.

Josh Allen is going to get very excited when watching the game film in anticipation of taking the field against a Titans defense that let up big plays, such as a 65-yard TD to Sterling Shepard.

The Bills’ defense will key on containing Derrick Henry and should force the mediocre Tennessee passing game into adverse situations. Buffalo will roll up points quickly and not surrender much as the Bills move out to a comfortable halftime lead.

Week 2 NFL Player Props

Gabriel Davis: Anytime TD Scorer (+105) vs Titans at DraftKings Sportsbook

WAGER: 2 Units

Davis is a TD and big-play machine who will deliver a big breakout campaign in 2022, after signaling it was coming in the playoffs last season with a four-TD outing. He got the scoring started in the season opener for Buffalo with a 26-yard TD reception.

Finding the end zone should be even easier against Tennessee than it was against the Rams, as we previously noted the Shepard bomb vs Tennessee for a score in Week 1. If you are feeling realty gutsy, you can take Davis to score twice at a tempting (+650).

Chase Edmonds: Over 11.5 Rushing Attempts (+105) vs Ravens at DraftKings

WAGER: 1 Unit

Edmonds is the clear lead running back for the Dolphins, as he had 12 carries to five for Raheem Mostert last week. He only gained 25 yards, but Miami needs to keep the Baltimore defense honest while trying to take pressure off Tua Tagovailoa. The Dolphins will continue to attempt to run the ball and achieve better offensive balance.

Michael Carter rushed for six yards per carry on 10 attempts in Week 1 against the Ravens, so Edmonds can produce better this week with ample work. Handing Edmonds the ball frequently enough to keep him in a rhythm can help him provide at least respectable production.

Baker Mayfield: Over 1.5 TD Passes (+135) vs Giants at DraftKings

WAGER: 2.5 Units

Mayfield has a pretty good crew of playmakers around him, making this a strong wager after Ryan Tannehill passed for two scores against the Giants last week. Robby Anderson caught a 75-yard TD pass from Mayfield in Week 1, and of course, Christian McCaffrey is always a significant threat to take a reception for a score from anywhere on the field.

D.J. Moore has never caught more than four TD passes in a season, but he could establish a new career high in that department working with Mayfield this season.

Allen Robinson: 1st TD Scorer (+700) vs Falcons at DraftKings

WAGER: 1 Unit

When a good wide receiver has a bad game, his quarterback will make it a point to get him involved quickly and frequently in the following game. Robinson’s quiet opening week set social media ablaze with widespread theories about why he fizzled out.

Robinson will silence the naysayers this week in a much better matchup and show why the Rams viewed him as a quality complement to Cooper Kupp when they signed him in the offseason. Taking Robinson at (+100) to go Over 53.5 receiving yards is the safer play and is also recommended, but we believe that he and Stafford will connect for an early statement score in Week 2.

Trey Lance: Over 1.5 Passing TDs (+140) vs Seahawks at DraftKings

WAGER: 2 Units

Lance did not throw a TD pass in the season opener, but the weather obviously played a big factor in his performance. Seattle allowed one TD pass to Russell Wilson on Monday. The Seahawks defense may indeed be better than many projected, but Lance needs to deliver a quality outing to show he can hold onto the starting job.

Lance’s wide receivers, Deebo Samuel and Brandon Aiyuk, will be the keys to helping you cash in here, as they should match up well with the Seattle secondary. Ultimately, Lance cannot let the 49ers head into a date with the Broncos at 0-2, and he must show he can lead his team to an important win.

Albert Okwuegbunam: Anytime Touchdown Scorer (+180) vs Texans at DraftKings

WAGER: 1.5 Units

Wilson showed a new willingness to get the ball more frequently to his tight ends in Week 1. As opponents try to take away his deep strikes and focus heavy attention on the WRs, Wilson may opt to go to other open targets in a revised approach. He often tried to create big plays instead of taking what the defense gave him in the past with the Seahawks.

Okwuegbunam nearly scored in Week 1, and the highly vulnerable Houston pass defense allowed two TD catches to O.J. Howard in their opener.

Cordarrelle Patterson: Over 53.5 Rushing Yards (+120) vs Rams at DraftKings

WAGER: 2 Units

Patterson appears to have recaptured his better form again, and he rushed for 120 yards in what was perceived to be a very challenging matchup against New Orleans. Devin Singletary rushed for 48 yards on just eight carries against the Rams in Week 1, and even if Patterson doesn’t approach 100 yards this week, he should be able to vault past this projected number.


Scott Engel

Scott Engel is a Senior Sports Writer at The Game Day. Previously he was at and The Athletic. His work is also featured at RotoBaller and on Scott is a host on SiriusXM Fantasy Sports Radio. He is an inaugural member of the Fantasy Sports Writers Association's Hall of Fame. Scott is a four-time FSWA award winner and a 13-time finalist. He was an Associate Editor and featured writer at and his career began at CBS SportsLine, where he was a Senior Writer and Managing Editor. Scott was the Managing Director at RotoExperts.

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