Portugal vs Uruguay World Cup Predictions

Last Updated: Nov 28, 2022

The two favorites to emerge from Group H will collide when European giants Portugal take on South American side Uruguay at the Lusail Stadium, with kickoff scheduled for 2 p.m. ET on Monday, Nov. 28.

With both teams being favored to win their opening group match, this fixture could present an opportunity for one nation to essentially secure a spot in the knockout round with a game to spare.

Let’s dig into this matchup further to pick out our Portugal vs Uruguay best bets for the second Group H clash of the 2022 World Cup.

Portugal vs Uruguay Odds

  • 3-Way Handicap: Portugal (+100) | Draw (+220) | Uruguay (+250)
  • Draw No Bet: Portugal (-210) | Uruguay (+160)
  • Over/Under Goals: Over 2.5 (+112) | Under 2.5 (-156)

Portugal vs Uruguay odds are current as of 3:15 p.m. ET on Wednesday, Nov. 9.

World Cup betting fans will see that sportsbooks are expecting a low-scoring game, with Portugal the more likely of the two sides to emerge victorious. However, the Correct Score market tells us that the result most likely to occur is a 1-1 draw (+500), followed closely by a 1-0 Portugal win (+600) and a 0-0 draw (+700).

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Portugal vs Uruguay Prediction

Portugal 2-1 Uruguay

These two nations last met four years ago in the Round of 16, with Uruguay emerging victorious by a 2-1 scoreline on the back of a brace from striker Edinson Cavani. A further examination of the stats, however, shows that it was a bit of a smash-and-grab performance.

Portugal had 67% possession, outshot Uruguay 20-5 (5-3 on target), and created way more chances. Cavani’s clinical finishing, however, proved to be the difference as Uruguay advanced to the Quarterfinals, where they fell to eventual champions France.

I’m expecting things to go a bit differently this time around, as Fernando Santos‘ side looks to exact some measure of revenge.

Portugal vs Uruguay Betting Tips

After rewatching highlights of their 2018 meeting in Sochi, I found the game to be more open than I would have expected it to be. Given the stakes of the occasion and Uruguay’s tendency to play more conservatively, I was surprised at the number of chances Portugal created in open play.

I also think there may be something to the second group game being slightly more high-scoring. In 2018, 9-of-16 games at this stage saw three-plus goals scored, while a further three finished with exactly two total goals scored.

This could be the sweet spot for Overs in the three-game group stage, with both teams typically fighting nerves in the opener and the pressure to advance in the third game with the knockout stage looming.

Portugal vs Uruguay Best Bets

Over 2.5 Goals (+112) at FanDuel Sportsbook

WAGER: 1 Unit

There will be world-class finishers on the field for both teams in this game, so even if the number of chances is limited, the ball could very likely still find its way into the back of the net multiple times.

Cavani, former Liverpool striker Luis Suárez, and current Reds forward Darwin Núñez are more than capable of converting chances that Uruguay creates, while Portugal’s star man Cristiano Ronaldo always rises to the occasion for his country.

Plus, Portugal has enticing attacking options on the wings in Manchester City’s Bernardo Silva and AC Milan youngster Rafael Leão, who could really burst onto the scene in Qatar.

Draw No Bet: Portugal (-210) at FanDuel Sportsbook

WAGER: 1 Unit

Given the odds, I would probably try to parlay this with another game, but I think this is a pretty safe bet.

Portugal has had four years to stew on its Round of 16 defeat in Russia, and it was pretty clearly the more talented side on that day. Uruguay’s forwards and defense are getting up there in age, and while Portugal has some injury issues of its own to worry about, they should get the job done.


John Arlia

Before joining The Game Day, John served as the National Writer for the United Soccer League, where he primarily covered the USL Championship out of the league’s headquarters in Tampa, FL. A devout soccer fan, John attended the men’s World Cups in Brazil and Russia and can’t wait for the 2026 edition to come to North America. Having also written for Sporting News Canada since getting his master’s from the Walter Cronkite School of Journalism at ASU, John has acquired a diverse sporting background, but considers football, golf, and soccer his three strong suits.

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