NFL Week 8 Odds & Opening Lines

Tim HeaneyDirector of Sports Content
Last Updated: Jan 23, 2023

NFL’s Week 8 schedule features a rematch of the 2022 NFC Championship Game between NFC West-rival San Francisco 49ers and defending Super Bowl champion Los Angeles Rams.

Week 8 also sees possible Super Bowl 57 matchups on Thursday Night Football and Monday Night Football, along with the Jacksonville Jaguars hosting their annual “home" game in London for the International Series.

The Kansas City Chiefs and Los Angeles Chargers are on their bye week, depriving us of watching two of the league’s best offenses.

Still, football bettors will find plenty of action to play among these Week 8 NFL odds and lines.

Week 8 NFL Odds & Lines

Keep tabs on all of our current NFL odds leading into NFL Week 8, which will change periodically on our football odds comparison module.

Week 8 lines referenced below are current as of Monday, Oct. 24, at 9 a.m., over on FanDuel Sportsbook.

Week 8 NFL Games

Baltimore Ravens @ Tampa Bay Buccaneers (Thursday Night Football)

Ravens -1.5 (-106) @ Buccaneers +1.5 (-114)

During the preseason, this looked like a matchup of possible NFL MVP favorites with the Bucs’ Tom Brady and the Ravens’ Lamar Jackson. Unfortunately, both quarterbacks have looked stuck in the mud in their stats columns the past few weeks.

Still, despite their uninspiring records, the 4-3 Ravens and 3-4 Buccaneers sit tied for first place in their respective divisions, so this primetime clash boasts plenty of stakes.

This line has flipped on its head since August from the Bucs -3.5, given Tampa Bay’s struggles in nearly every facet of football in losing four of their past five games.

I’d more so target player props in this one than bet too strongly on any traditional wager.

Denver Broncos @ Jacksonville Jaguars (Sunday, Oct. 30, 9:30 a.m. ET - LONDON)

Broncos +3.5 (-110) @ Jaguars -3.5 (-110)

Betting on the jetlag-fueled London games typically throws betting off-kilter.

The Jaguars will be playing their league-high sixth London game, meaning they have experience in the travel wrench thrown into their schedule.

The Broncos may not have QB Russell Wilson (hamstring), who missed Week 7. For all of Russ’ terrible cooking this year, Denver looked lost on offense without him.

Still, I don’t like the Jags already taking more than a field goal’s worth of points on the spread.

Carolina Panthers @ Atlanta Falcons (Oct. 30, 1 p.m. ET)

Panthers +6.5 (-110) @ Falcons -6.5 (-110)

Before Week 7, Carolina traded star running back Christian McCaffrey in a headline step of its firesale.

Atlanta’s tepid offense makes it look like they’re in the middle of their own tanking, but the 3-4 Falcons are oddly tied for first place with the Bucs in the NFC South.

And with all its absurdities, Atlanta is tied for the league lead with a 6-1 record against the spread.

Even with Carolina rolling over, not sure -6.5 makes me happy for Atlanta’s side.

Chicago Bears @ Dallas Cowboys

Bears +10.5 (-110) @ Cowboys -10.5 (-110)

Speaking of boring offenses, Chicago hasn’t generated much excitement for Justin Fields.

The Cowboys, meanwhile, treaded water with Cooper Rush before Dak Prescott’s Week 7 return from a thumb fracture, which helped Dallas’ offense look closer to what many pundits expected.

The preseason Dallas -7 line wasn’t a true bargain but was better than a double-digit overreaction after their win against the Lions. Of course, Dallas’ defense maintains a major advantage over a sloppy Chicago offense.

I’ll pivot off less favorable general odds by targeting a win margin for the Cowboys. Keep an eye on those props when they come out.

Miami Dolphins @ Detroit Lions

Dolphins -3.5 (-110) @ Lions +3.5 (-110)

Tua Tagovailoa returned in Week 7 after recovering from tumultuous concussion issues, and despite scoring just 16 points, Miami’s offense looked like its “typical” self.

Detroit has suffered on offense without RB D’Andre Swift (ankle, shoulder), who has a chance to return in Week 8.

However, the Lions might be without top wideout Amon-Ra St. Brown, who suffered a concussion of his own Sunday.

Maybe I’ll take a chance if it dips to something around 47, but the reputation of Miami’s offense will likely keep the total at 50.5, which remains too high for me.

The Under looks great here, especially if Detroit’s two offensive stars don’t return.

Arizona Cardinals @ Minnesota Vikings

Cardinals +3.5 (-106) @ Vikings -3.5 (-114)

Arizona thumped the New Orleans Saints on TNF thanks in part to the returning DeAndre Hopkins. He’ll help ‘Zona get through the weeks-long absence of Marquise Brown (foot).

However, traveling to face Minnesota, who’s coming off a bye, presents a major defensive disadvantage with a rested Kirk Cousins, Justin Jefferson, and Dalvin Cook.

How much would buying Vikings -2.5 cost you? Pairing it with another leg in a parlay would help it pay more.

Las Vegas Raiders @ New Orleans Saints

Raiders -1.5 (-114) @ Saints +1.5 (-106)

The Saints’ quarterback may determine this lean. Will Jameis Winston (back, ankle) move Andy Dalton to the bench? Will WR Michael Thomas (foot) return?

Las Vegas will use Davante Adams and Josh Jacobs as much as possible on offense, and that might be enough to keep them competitive regardless of New Orleans’ injury report.

Still, I would take the chance that Winston and Thomas return, which would likely give Saints +1.5 sprinkle-bettors closing line value.

New England Patriots @ New York Jets

Patriots -2.5 (-110) @ Jets +2.5 (-110)

This might shift after the Patriots vs Bears MNF, but these odds haven’t changed since the summer.

The Jets are 5-2 despite Zach Wilson‘s struggles under center, and they’ve just lost excellent rookie RB Breece Hall with a torn ACL.

If pressed, I would lay the (reasonable) wood with the Pats on the road here before that line climbs, but it’s not one of my favorite bets in this article.

Pittsburgh Steelers @ Philadelphia Eagles

Steelers +10.5 (-110) @ Eagles -10.5 (-110)

Pennsylvania online betting will be amped up for this interconference but intrastate meeting.

The Eagles are defending their home turf off a bye while facing rookie quarterback Kenny Pickett.

I rue when this line read Eagles -3.5 this summer. Buy Eagles points, build a PHI ML parlay, or target player props for optimal Steelers vs Eagles pick value.

Tennessee Titans @ Houston Texans (Oct. 30, 4:05 p.m. ET)

Titans -2.5 (-104) @ Texans +2.5 (-118)

Divisional game aside, this feels like a gimme line to snag for the Titans, who just upended the Colts in Week 7.

Houston (1-4-1) has little home-field advantage to care about, given their many personnel holes. Derrick Henry should control this affair.

The hook below the field goal for this ATS bet is stunningly favorable. This spread is going to climb strongly in Tennessee’s favor as the week progresses. Pounce.

Washington Commanders @ Indianapolis Colts

Commanders +3 (-105) @ Colts -3 (-115)

August writeup: “The Carson Wentz Bowl. Lol. He might not even be under center against his 2021 Colts team by this point.”

Cut to Week 8: Wentz is out for a few weeks, with Taylor Heinicke taking snaps ahead of meeting the Colts.

Indy has benched dead-armed Matt Ryan in favor of Sam Ehlinger. Maybe that’s a split-the-difference development? Not sure it helps.

Jonathan Taylor should help the Colts dictate play – but a possible return of Washington defensive end Chase Young (knee) would further scare me away from giving a flawed Indy club that many points.

The spread has already shifted; I don’t care at the moment. But run to bet Under on any total higher than 39.

San Francisco 49ers @ Los Angeles Rams

49ers -1.5 (-114) @ Rams +1.5 (-106)

NFC Championship rematch alert, but we’re already seeing a huge change from that January matchup.

The five-point swing of these 49ers-Rams odds toward San Francisco since August is the result of numerous factors, including a Rams team going through a Super Bowl winner hangover (weak offensive line, lack of contributions from Allen Robinson, and more issues).

The 49ers traded for Christian McCaffrey before Sunday and will look to expand his playbook for this crucial NFC West battle.

Luckily, since the preseason, the Over/Under has toppled down to 41.5, which makes me want to buy the Over. The Rams are coming off a bye, which could give them an offense that looks closer to the Lombardi Trophy-winning unit under Matthew Stafford.

New York Giants @ Seattle Seahawks

Giants +2.5 (-104) @ Seahawks -2.5 (-118)

Two of the NFL’s most surprising teams square in what’s become an afternoon-slate co-headliner. The Giants are 6-1 and sit near the top of the NFC East, while Seattle sits 4-3 atop the vaunted NFC West.

New Giants head coach Brian Daboll and emergent Seattle QB Geno Smith have reinvigorated their franchises. This will mark a significant test of which team is more “for real.”

The lines haven’t changed much since August, but the betting interest likely will surge. The cross-country travel for the Giants might bulk up Seattle’s given points, which in turn might make the Giants the better late-week buy.

Green Bay Packers @ Buffalo Bills (Sunday Night Football)

Packers +10.5 (-110) @ Bills -10.5 (-110)

Anyone who landed Buffalo -4 in the preseason is cackling at the moment. The Packers have done little to help Aaron Rodgers with surrounding talent on both sides of the ball, while Buffalo continues to carry some of the shortest Super Bowl odds to win.

The Bills rank second with a 14-8-2 ATS record as a home favorite in the Josh Allen era but see how you can tease this spread down to a more manageable figure.

Green Bay still boasts a run game that, if used logically, could help keep Green Bay competitive and cut into that double-digit spread.

Cincinnati Bengals @ Cleveland Browns (Monday Night Football)

Bengals -3 (-118) @ Browns +3 (-104)

Cleveland continues to lean on running back Nick Chubb, wideout Amari Cooper, and its often talented defense. They’ll need to slow the pace down to cool red-hot Joe Burrow and Ja’Marr Chase on the other side.

I fear a bit about the Browns’ pass rush versus the Bengals’ weak offensive line, but the QB advantage for Cincy doesn’t play strongly enough for these MNF odds.


Tim Heaney

Before joining The Game Day, Tim spent more than a decade in the fantasy sports and betting industry. Having written for ESPN, RotoWire, and USA TODAY, Tim earned an FSWA award nomination for Best MLB Print Article and multiple Top-5 finishes in fantasy baseball rankings contests. Tim has competed in Tout Wars (1 championship), LABR, Scott Fish Bowl, NFBC/NFFC, TGFBI, and RazzBowl (recent 4th-overall finish out of 200+). Drop him a line about TV, music, craft beer & pro wrestling.

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