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NFL Week 8 Odds | Opening NFL Moneyline, Spread, & Total Betting Lines

Tim HeaneyManaging Editor
Posted: Jul 12, 2022Last updated: Aug 25, 2022

NFL’s Week 8 schedule features a rematch of the 2022 NFC Championship Game between NFC West-rival San Francisco 49ers and defending Super Bowl champion Los Angeles Rams.

Week 8 also sees possible Super Bowl 57 matchups on Thursday Night Football and Monday Night Football, along with the Jacksonville Jaguars hosting their annual “home" game in London for the International Series.

The Kansas City Chiefs and Los Angeles Chargers are on their bye week, depriving us of watching two of the league’s best offenses.

Still, football bettors will find plenty of action to play among these Week 8 NFL odds and lines. Sure, we’re writing these in the preseason, but I’m happy to offer my early leans for each of these Week 8 games.

Week 8 NFL Odds & Lines

Week 8 NFL odds are courtesy of Betway Sportsbook unless otherwise noted and are current as of Monday, August 8 at noon ET. Be sure to keep tabs on all of our current NFL odds leading into NFL Week 8.

Week 8 NFL Games

Baltimore Ravens @ Tampa Bay Buccaneers (Thursday Night Football)

Ravens +3.5 (-110) @ Buccaneers -3.5 (-110)

This could become a pivotal point in the NFL MVP discussion as the Bucs’ Tom Brady hosts the devastating weapon that is Ravens QB Lamar Jackson.

Though Jackson will test the Buccaneers’ excellent defense, expect the home team to hold them off.

Wait for that -3.5 spread to dip, though, or find an alternate line and lean toward Brady’s Bucs, who are 14-5 at Raymond James Stadium (including postseason) under his guidance.

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Denver Broncos @ Jacksonville Jaguars (Sunday, Oct. 30, 9:30 a.m. ET in LONDON)

Broncos -6.5 (-110) @ Jaguars +6.5 (-110)

Betting on the jetlag-fueled London games typically throws betting off-kilter.

The Jaguars also will be playing their league-high sixth London game. The books priced them this way, though: The spread dipped from Jags +7 to Jags +6.5 this past week, so that’s the wrong direction for the hook. No major qualms if you want a minimum-unit bet there, though.

However, play any Over with a total up to 43.5.

Russell Wilson‘s arrival elevates Denver’s offense to finally extract elite potential from wide receivers Courtland Sutton and Jerry Jeudy; standout running back Javonte Williams; and breakout candidate TE Albert Okwuegbunam.

The Jags’ offense should take its own step forward in Trevor Lawrence‘s second season under a competent head coach (especially for offenses) in Doug Pederson and running backs Travis Etienne (Clemson teammate) and James Robinson.

Carolina Panthers @ Atlanta Falcons (Oct. 30, 1 p.m. ET)

Panthers -1.5 (-110) @ Falcons +1.5 (-110)

A game only bettors and fantasy football players could love: The Baker Mayfield-Sam Darnold QB battle has held court in Carolina, while Marcus Mariota replaces Matt Ryan under center in Atlanta.

This NFC South matchup still has plenty of star power, including Panthers RB Christian McCaffrey and Falcons TE Kyle Pitts, and these defenses should suffer on the turf.

Given these two flawed teams rank closely in level of talent, the best betting course involves teasing the Over/Under total to something below 40 and hope garbage time lends a hand in topping it.

Chicago Bears @ Dallas Cowboys

Bears +7 (-110) @ Cowboys -7 (-110)

Justin Fields will have to deal with the Cowboys’ aggressive, takeover-centric defense led by possible Defensive Player of the Year candidate Micah Parsons.

I’m not fully confident clicking Bears (+240) to win, but their rushing offense, led by David Montgomery and Khalil Herbert, should keep things close against a less-than-stellar Cowboys run defense and take the ball out of Dak Prescott‘s hands.

Hopefully teasing that spread up to Chicago +7.5 doesn’t cost too much, though we might be able to snag Closing Line Value at +8 or better in the first few weeks of the season or early in Week 8.

Miami Dolphins @ Detroit Lions

Dolphins -3 (+100) @ Lions +3 (-120)

Will Tua Tagovailoa remain the quarterback by this point? He’s set up to succeed in a crucial year thanks to a stacked offense led by new arrival Tyreek Hill.

This is a possible trap game on the road for them, given that the Lions have the run game to dictate the pace, especially with potential breakout RB D’Andre Swift.

Of course, Miami has a speedy team built to thrive on FieldTurf. Seek out favorable team points totals and consider betting any Over above 45.

Arizona Cardinals @ Minnesota Vikings

Cardinals +1 (-110) @ Vikings -1 (-110)

Barring further health complications, DeAndre Hopkins (knee) will be on his second game back from his six-game suspension to open the season. However, will Kyler Murray have Marquise Brown, who recently ran into legal trouble?

He’ll likely need the talented deep threat to compete with the home team’s quartet of QB Kirk Cousins; WRs Justin Jefferson and Adam Thielen; and RB Dalvin Cook.

The spread might shift to a PICK, which is fine. More value could come from an Over 48.5 or better, given the strength of these offenses in an indoor, track-meet setting.

Las Vegas Raiders @ New Orleans Saints

Raiders PICK (-110) @ Saints PICK (-110)

The Caesars Superdome should brace for ample offense. QB Derek Carr welcomes former college teammate Davante Adams this season to join an already impressive group with TE Darren Waller and WR Hunter Renfrow.

Jameis Winston‘s outlook by this point depends on whether Alvin Kamara‘s upcoming trial keeps getting postponed and Michael Thomas has surmounted his injury issues.

Either way, an Over 48.5 feels like my first inkling to bet, and I would probably stop at 51.5 as long as the juice is (-110) or better.

New England Patriots @ New York Jets

Patriots -2.5 (-110) @ Jets +2.5 (-110)

Two sophomore AFC East quarterbacks meet again: The Pats’ Mac Jones and the Jets’ Zach Wilson tangle manning talented but transitional teams.

It’s best to wait this one out, given how much is in flux for the Patriots’ passing game.

Perhaps the Under will work. However, if I’m forced to place a preseason bet, I would target NFL props like Damien Harris‘ Over rushing yards total.

Pittsburgh Steelers @ Philadelphia Eagles

Steelers +3.5 (+100) @ Eagles -3.5 (-120)

Pennsylvania betting will be amped up for this interconference but intrastate meeting.

Given the Steelers’ bleak QB picture between Mitchell Trubisky and Kenny Pickett, fade Pittsburgh’s ability to fend off an aggressive Eagles defensive line.

Ride Jalen Hurts to an easy ATS spread of Eagles -3.5 (-120).

Tennessee Titans @ Houston Texans (Oct. 30, 4:05 p.m. ET)

Titans -5.5 (-110) @ Texans +5.5 (-110)

The Titans’ offense may find it tough to replace A.J. Brown through the air, but Derrick Henry always boasts the threat to carry a game if on the field.

However, don’t count out a Texas team led by sneaky-talented QB Davis Mills and the perennially underrated Brandin Cooks.

If they can get any semblance of a run game going ahead of this contest, HOU +5.5 could become a major value if it holds or improves on the points-given side.

Washington Commanders @ Indianapolis Colts

Commanders +5 (-110) @ Colts -5 (-110) 

The Carson Wentz Bowl. Lol. He might not even be under center against his 2021 Colts team by this point.

Maybe Washington can play keepaway with the run game to limit the possession of Matt RyanJonathan Taylor, and Michael Pittman. I’m not banking on it.

Indy should plow through Washington at home. HAMMER that IND -5 (-110).

San Francisco 49ers @ Los Angeles Rams

49ers +4.5 (-110) @ Rams -4.5 (-110)

Mixed among an erratic Week 8 schedule is the final regular-season edition of the NFC West rivalry and another rematch of the 2022 NFC Championship Game — which could have significant implications in one of the NFL’s best divisions. (OK, maybe not the Seahawks.)

Matthew Stafford could find more success through the air with the addition of Allen Robinson as a complement to last year’s star Cooper Kupp.

The major sticking point here: How effective has presumptive starting QB Trey Lance been? Has he proven he can handle the major hurdle of evading future Hall of Famer Aaron Donald on the pass rush?

Are we back to Jimmy Garoppolo quarterbacking for the Niners?

San Francisco can hang — they were a few breaks from making the Super Bowl instead of the LAR — but +4.5 isn’t enough for me to back. I’m waiting this out but trending toward the Rams covering.

New York Giants @ Seattle Seahawks

Giants +2.5 (-110) @ Seahawks -2.5 (-110)

Here we thought the Panthers-Falcons was going to be a slog.

By this point, will Daniel Jones have shown signs of life in Brian Daboll‘s offense? Will Drew Lock or Geno Smith (or someone else?) show a capacity to run Seattle’s offense?

Not sure the 12th Man matters too much here. The Under will play as long as the total sits above 36.

Green Bay Packers @ Buffalo Bills (Sunday Night Football)

Packers +4 (-110) @ Bills -4 (-110)

Aaron Rodgers visits Josh Allen on the big stage and will have to deal with the league’s top pass defense from 2021.

This might come down to a matchup of the run games, where the Packers hold a distinct advantage if Aaron Jones and A.J. Dillon are active.

Backing the Jones-Dillon pair, the Under and the Packers’ ATS are in play. Even if Buffalo sports cold weather in this NBC primetime clash, Green Bay is well used to such obstacles.

Cincinnati Bengals @ Cleveland Browns (Monday Night Football)

Bengals N/A @ Browns N/A

As of our August publish date, many Browns odds are off the books due to the league’s ongoing Deshaun Watson suspension appeal.

We will update our outlook here once we know who will be under center. Watson was originally scheduled to take snaps in Week 8 after his initially designated six-game suspension, though the NFL is reportedly seeking a longer ban.

Either way, seek how many points the Bengals eventually get. If it’s anything above 3.5, it makes laying the wood more difficult.


Tim Heaney

Before joining The Game Day, Tim spent more than a decade in the fantasy sports and betting industry. Having written for ESPN, RotoWire, and USA TODAY, Tim earned an FSWA award nomination for Best MLB Print Article and multiple Top-5 finishes in fantasy baseball rankings contests. Tim has competed in Tout Wars (1 championship), LABR, Scott Fish Bowl, NFBC/NFFC, TGFBI, and RazzBowl (recent 4th-overall finish out of 200+). Drop him a line about TV, music, craft beer & pro wrestling.

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