NFL Week 3 Odds

Frank AmmiranteSenior Sports Writer
Last Updated: Sep 18, 2023

The NFL schedule has been released, so we can take a look at the betting lines for each week, including Week 3.

This is a week with a full slate of games since there aren’t any teams on the bye. We can take advantage of opening lines since we’re likely to see odds shifts as we get closer to game time.

Here are the current Week 3 NFL odds and lines for the 2023 season.

NFL Week 3 Odds & Lines

Week 3 lines are courtesy of DraftKings Sportsbook and are current as of Monday, Sept. 18, at 5 p.m. ET.

Keep tabs on all of our current NFL odds leading into NFL Week 3.

NFL Week 3 Games

New York Giants @ San Francisco 49ers

Sept. 21, 8:15 p.m. ET (TNF)

  • Giants +10.5 (-110) @ 49ers -10.5 (-110)

The Giants narrowly avoided an 0-2 start with a comeback win over the Cardinals in Week 2, while the 49ers look like the best team in football, winning their first two games of the year.

New York will be in a tough spot on the road with a short week, especially with top weapon Saquon Barkley likely out for this game.

While 10.5 is a lot of points, the 49ers look like the safer play here.

Houston Texans @ Jacksonville Jaguars

Sept. 24, 1 p.m. ET

  • Texans +8.5 (-108) @ Jaguars -8.5 (-112)

The Texans are off to an 0-2 start, held back by a depleted offensive line that has made their running game virtually non-existent. On the bright side, C.J. Stroud has shown some promise, throwing for 384 yards against the Colts last week.

The Jaguars are coming off a home loss to the Chiefs, looking to bounce back in a favorable spot against the Texans. Having said that, 8.5 points feels like a lot in an AFC South divisional game, so I prefer taking Houston to cover the spread.

Indianapolis Colts @ Baltimore Ravens

Sept. 24, 1 p.m. ET

  • Colts +7.5 (+100) @ Ravens -7.5 (-120)

Rookie quarterback Anthony Richardson looks like the real deal so far, but he’s dealing with a concussion. If he can’t play, Gardner Minshew can hold down the fort since he’s one of the best backups in the NFL.

The Ravens are off to a 2-0 start, fresh off of a huge divisional win against the Bengals. While they should get it done at home here, we can’t rule out the Colts, who look great on offense under new head coach Shane Steichen.

Look for the Colts to put a scare into Baltimore here, making them a nice play at +7.5.

Buffalo Bills @ Washington Commanders

Sept. 24, 1 p.m. ET

  • Bills -6.5 (-115) @ Commanders +6.5 (-105)

The Bills predictably blew out the Raiders as they avoided a 0-2 start last week, while the Commanders upset the Broncos en route to a surprising two-game winning streak to start off the year.

Washington will have its hands full against one of the best teams in the NFL. As long as Josh Allen avoids ill-advised turnovers, Buffalo should get it done.

Bills -6.5 looks like a great play considering the talent disparity of these two teams, so roll with Buffalo in our NFL bet of the day.

Los Angeles Chargers @ Minnesota Vikings

Sept. 24, 1 p.m. ET

  • Chargers -1 (-105) @ Vikings +1 (-115)

Here we have a matchup of two playoff contenders in must-win situations, each starting off the year at 0-2.

The Chargers are the better team, coming off two close losses that they could have easily won. Meanwhile, the Vikings have been turnover-prone on offense, posting an average of 3.5 per game.

This game could come down to the wire, but the Chargers look like the better play at -1.

New England Patriots @ New York Jets

Sept. 24, 1 p.m. ET

  • Patriots -3 (-108) @ Jets +3 (-112)

The Jets are 3-point home underdogs due to how much Zach Wilson brings down this offense. We’ve seen the third-year quarterback struggle since taking over for the injured Aaron Rodgers, throwing four interceptions to two touchdowns.

The Patriots have an improved offense, but they don’t have any game-breakers on that side of the ball. It’s hard to feel confident laying points on the road with this team.

New York’s defense is among the best in the NFL and can win a game on their own. Jets +3 looks like the safer play here.

Atlanta Falcons @ Detroit Lions

Sept. 24, 1 p.m. ET

  • Falcons +3.5 (-112) @ Lions -3.5 (-108)

The Falcons should be able to find success against the Lions with their efficient running game, but can Desmond Ridder do enough through the air to keep pace with Jared Goff and company?

Lions running back David Montgomery is expected to miss this game, which could result in more passing volume and an uptick in touches for promising rookie Jahmyr Gibbs.

Ridder doesn’t have the goods to keep pace in a shootout. Give me the Lions -3.5.

Tennessee Titans @ Cleveland Browns

Sept. 24, 1 p.m. ET

  • Titans +4 (-110) @ Browns -4 (-110)

The Titans came from behind to knock off the Chargers, but they’re in a tough spot on the road against the Browns.

I’m not buying into Tennessee following their upset over Los Angeles, either. They’re still one of the worst teams in the NFL.

On the other hand, Cleveland looks like a playoff contender, so taking the Browns -4 is the preferred play.

New Orleans Saints @ Green Bay Packers

Sept. 24, 1 p.m. ET

  • Saints +2 (-110) @ Packers -2 (-110)

The Packers come back home after a tough loss in Atlanta, but they have to be content with their 1-1 start on a two-game road trip. Quarterback Jordan Love has been impressive so far, throwing six touchdowns with zero interceptions.

New Orleans is in a tough spot on a short week to come to Lambeau, so we’ll take the Packers -2.

Denver Broncos @ Miami Dolphins

Sept. 24, 1 p.m. ET

  • Broncos +6.5 (-110) @ Dolphins -6.5 (-110)

The Dolphins look like an AFC juggernaut. Tua Tagovailoa is playing efficiently, and the running game looks strong behind Raheem Mostert.

Denver just dropped two games in a row at home, but the offense looked much better in Week 2 in a tough loss vs the Commanders.

Having said that, the Broncos are no match for Miami here. Take the better team at a reasonable spread of only 6.5 points. This is personal for Dolphins defensive coordinator Vic Fangio, who used to coach in Denver.

Carolina Panthers @ Seattle Seahawks

Sept. 24, 4:25 p.m. ET

  • Panthers +4.5 (-110) @ Seahawks -4.5 (-110)

The Panthers are on the right track, pairing franchise quarterback Bryce Young with a young and talented defense.

However, this is a tough game on the road against Geno Smith and a Seahawks team that is coming off an impressive road win over Detroit — despite playing without their two starting offensive tackles.

Roll with the Seahawks -4.5.

Dallas Cowboys @ Arizona Cardinals

Sept. 24, 4:25 p.m. ET

  • Cowboys -12.5 (-110) @ Cardinals +12.5 (-110)

It’s hard to see how Joshua Dobbs and the Cardinals are going to move the ball against one of the elite defenses in the NFL.

The Cowboys have shut down the Giants and Jets in their first two games. They now face an offense that is even worse.

Arizona blew a 20-point lead to the mediocre Giants, so don’t expect much from them here. Dallas -12.5 looks like the play here.

Chicago Bears @ Kansas City Chiefs

Sept. 24, 4:25 p.m. ET

  • Bears +13.5 (-112) @ Chiefs -13.5 (-108)

The Bears have looked like an absolute dumpster fire in their first two games, losing to the Packers and Buccaneers — two teams many believed would miss the playoffs.

It’s hard to envision a scenario where a struggling Justin Fields can keep pace with Patrick Mahomes and the Chiefs.

Kansas City’s defense just limited Trevor Lawrence and the Jaguars to only nine points. Roll with KC -13.5.

Pittsburgh Steelers @ Las Vegas Raiders

Sept. 24, 8:20 p.m. ET (SNF)

  • Steelers -1 (-110) @ Raiders +1 (-110)

The Steelers will have to travel to the West Coast on a short week following Monday Night Football. It’s going to be tough for them without Diontae Johnson, one of their top wideouts.

However, they’re still better than the Raiders, who just got blown out by the Bills on the road.

I’ll go with the team with the superior defense in Pittsburgh. Expect the Steelers to get a much-needed road win.

Philadelphia Eagles @ Tampa Bay Buccaneers

Sept. 25, 7:15 p.m. ET (MNF)

  • Eagles -5.5 (-108) @ Buccaneers +5.5 (-112)

I’m not buying into Tampa Bay’s 2-0 start. These wins came against an abysmal Bears team and a turnover-prone Vikings side.

The Eagles haven’t been themselves on offense, but they have too much talent for me to pick against them in this game, especially with extra rest coming off Thursday Night Football.

Look for Philly’s pass rush to cause problems for Baker Mayfield, so give me the Eagles -5.5.

Los Angeles Rams @ Cincinnati Bengals

Sept. 25, 8:15 p.m. ET (MNF)

  • Rams +2 (-108) @ Bengals -2 (-112)

The Rams have been one of the biggest surprises so far. Matthew Stafford looks back to his Super Bowl form, and rookie sensation Puka Nacua has filled the Cooper Kupp void admirably.

Meanwhile, the Bengals are 0-2, and Joe Burrow has appeared to re-aggravate his calf injury. He hasn’t looked anywhere close to himself so far this season.

Los Angeles should probably be short favorites in this game — especially since Burrow may miss this one — so give me the Rams +2.


Frank Ammirante

Frank Ammirante is a Senior Sports Writer at The Game Day. Previously, he wrote for 4for4 Football and RotoBaller. Frank is a member of the Fantasy Sports Writer's Association while maintaining an active presence within the community. He has competed in industry contests like the Scott Fish Bowl, The Great Fantasy Baseball Invitational, and more. Frank will be making his debut in Tout Wars this year. He's got a diverse sporting background, but specializes in football and baseball.

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