NFL Week 14 Odds & Opening Lines

Posted: Dec 6, 2022Last updated: Dec 25, 2022

Just five weeks remain in the 2022 NFL regular season, but there is still so much at stake.

All 14 playoff spots are up for grabs (although that could change this week) and the race for the No. 1 seed in both conferences is likely to come down to the wire.

This week’s 13-game slate should help further clarify the NFL playoff picture and also represents the last time teams will have a bye as we head into the final month of the year.

Here are the current Week 14 NFL odds and lines for the 2022 season.

Week 14 NFL Odds & Lines

Week 14 NFL odds are courtesy of Caesars Sportsbook unless otherwise noted and are current as of Monday, Dec. 5, at 12 p.m. ET. Be sure to keep tabs on all of our current NFL odds leading into NFL Week 14.

Week 14 NFL Games

Las Vegas Raiders @ Los Angeles Rams (Thursday Night Football)

Raiders -5.5 (-110) @ Rams +5.5 (-110)

These two teams are heading in opposite directions.

The Raiders have won three straight games, while the Rams have lost six in a row and will likely start backup quarterback John Wolford for the second straight week.

Wolford and Los Angeles fought to the end of Sunday’s loss to the Seahawks, but it’s hard to back this depleted roster.

New York Jets @ Buffalo Bills (Dec. 11, 1 p.m. ET)

Jets +9.5 (-110) @ Bills -9.5 (-110)

The Bills will look to avenge their mid-season loss to Jets when they welcome Mike White and co. to Highmark Stadium on Sunday afternoon.

Buffalo’s offense managed just 17 points against this stingy Jets defense in that first meeting, and New York’s offense has improved since then, so winning by 10 or more may be a task too tall for Josh Allen.

Cleveland Browns @ Cincinnati Bengals

Browns +6 (-110) @ Bengals -6 (-110)

This feels like a great situational spot to back the Browns, especially with Cincinnati coming off an emotional victory over the Chiefs.

Cleveland is also coming off a win in Deshaun Watson‘s debut, but he had his defense and special teams to thank after an uninspiring performance. I’d expect to see a better version of him here.

Houston Texans @ Dallas Cowboys

Texans +17 (-110) @ Cowboys -17 (-110)

If you went to sleep early Sunday night, you probably missed the Cowboys scoring 33 points in the fourth quarter of their 54-19 win over the Colts. Now, they’ll get a Texans team that has already been eliminated from playoff contention and showed no signs of offensive life in their “Super Bowl" against Watson and the Browns last week.

Houston has an easy road to the No. 1 overall pick, and it should put up little resistance in this instate matchup, but this is a ton of points.

Minnesota Vikings @ Detroit Lions

Vikings +1 (-110) @ Lions -1 (-110)

Yes, you’re reading that right.

The 10-2 Vikings, who can clinch the NFC North on Sunday with a win, are slight underdogs at the 5-7 Lions. Detroit has played some really good football of late, especially at home, but this spread seems super fishy.

I would stay away.

Philadelphia Eagles @ New York Giants

Eagles -7 (-110) @ Giants +7 (-110)

The Giants are desperately trying to hold onto the final playoff spot in the NFC, while Jalen Hurts and the Eagles just keep on rolling. Philadelphia still has competition for the No. 1 seed, so it’s not like they’ll take this game lightly.

Teasing the Eagles down to -1 makes a lot of sense, but I’m not sure I can lay the full touchdown here.

Baltimore Ravens @ Pittsburgh Steelers

Ravens +2 (-110) @ Steelers -2 (-110)

The Steelers have won back-to-back games and three of four since their bye week. Meanwhile, Baltimore’s offense has struggled mightily of late and just lost Lamar Jackson to a knee injury in Sunday’s 10-9 win over the Broncos.

Tyler Huntley is a capable backup, but Pittsburgh is deservedly favored if Jackson can’t go.

Jacksonville Jaguars @ Tennessee Titans

Jaguars +3.5 (-110) @ Titans -3.5 (-110)

This feels like a game that in previous years Derrick Henry would run for 200-plus yards and multiple touchdowns. Whether that will be the case on Sunday remains to be seen, especially with both teams looking to bounce back from 20-plus point losses in Week 13.

I think Tennessee is the better team, but I’d wait to see if a three pops.

Kansas City Chiefs @ Denver Broncos (Dec. 11, 4:05 p.m. ET)

Chiefs -9 (-110) @ Broncos +9 (-110)

This game was originally scheduled for Sunday Night Football, which makes sense since it realistically could have been the one that decided the AFC West. Thankfully, since that hasn’t proven to be the case, the NFL spared us another primetime Broncos disaster.

This could certainly turn into a Kansas City bounce-back game, but just bet the Under and move on.

Carolina Panthers @ Seattle Seahawks

Panthers +3.5 (-110) @ Seahawks -3.5 (-110)

The Seahawks may look like the obvious pick in this spot, but the Panthers still technically have a shot at the NFC South, and quarterback Sam Darnold is playing for the starting job.

I think taking the points with Carolina coming off the bye is a good early-week investment.

Tampa Bay Buccaneers @ San Francisco 49ers

Buccaneers +3 (-110) @ 49ers -3 (-110)

This is one of the most important and interesting games of the week, although the season-ending foot injury to 49ers quarterback Jimmy Garoppolo certainly puts a damper on it.

Still, it will be fascinating to see how Tom Brady and the Buccaneers fare against this dominant San Francisco defense. Oddsmakers seem to believe the Tampa Bay offensive line will be overmatched, and I don’t disagree.

The Niners have enough playmakers to win and cover at home, especially with Tampa Bay coming off a short week. Take San Francisco as your NFL pick of the day.

Miami Dolphins @ Los Angeles Chargers (Sunday Night Football)

Dolphins -3 (-105) @ Chargers +3 (-115)

These AFC playoff hopefuls were served a sour dose of reality on Sunday. Miami had minimal answers for San Francisco’s defense in a 33-17 defeat, while Los Angeles couldn’t cover Davante Adams in a 27-20 loss to the Raiders.

Injuries have been an issue for the Chargers all season long, and if they don’t get key pieces in Corey Linsley and Mike Williams back in time for this SNF showdown, the Dolphins should be able to run this one up.

New England Patriots @ Arizona Cardinals (Monday Night Football)

Patriots -1 (-110) @ Cardinals +1 (-110)

The Patriots have had a hard time slowing down mobile quarterbacks this season, and Kyler Murray certainly falls into that category when healthy. However, that hadn’t particularly been the case before the bye, and Arizona seemingly can’t win home games for whatever reason.

I’d lean towards a desperate New England team, but I don’t feel that confident about it.


John Arlia

Before joining The Game Day, John served as the National Writer for the United Soccer League, where he primarily covered the USL Championship out of the league’s headquarters in Tampa, FL. A devout soccer fan, John attended the last two men’s World Cups in Brazil and Russia and can’t wait for the 2026 edition to come to North America. Having also written for Sporting News Canada since getting his master’s from the Walter Cronkite School of Journalism at ASU, John has acquired a diverse sporting background, but considers football, golf, and soccer his three strong suits.

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