NFL Week 10 Odds

Frank AmmiranteSenior Sports Writer
Last Updated: Nov 6, 2023

We’re now firmly in the second half of the season as we head into Week 10.

It’s highlighted by the second game in Germany in 2023 and the third overall, with the Indianapolis Colts and New England Patriots battling it out at Deutsche Bank Park in Frankfurt.

There are also other intriguing matchups, such as the Browns-Ravens and Lions-Chargers, so let’s take a closer look at the Week 10 odds and lines for the 2023 NFL season.

NFL Week 10 Odds & Lines

Week 10 lines are courtesy of Caesars Sportsbook and current as of Monday, Nov. 6, at noon ET.

Keep tabs on all of our current NFL odds.

NFL Week 10 Games

Carolina Panthers @ Chicago Bears

Nov. 9, 8:20 p.m. ET (TNF)

  • Panthers +3.5 (-110) @ Bears -3.5 (-110)

The Panthers continue to look like the worst team in the NFL, as rookie quarterback Bryce Young has had a disappointing season, coming off an abysmal performance vs a vulnerable Colts’ defense.

The Bears nearly pulled off the upset over the New Orleans Saints behind a strong effort from backup Tyson Bagent, who will likely start for another week in place of Justin Fields.

The Bears would benefit from beating up on the Panthers here since they hold Carolina’s first-round pick, which may be first overall. Roll with Chicago in this spot.

Indianapolis Colts @ New England Patriots

Nov. 12, 9:30 a.m. ET (Frankfurt, Germany)

  • Colts -2 (-110) @ Patriots +2 (-110)

The Colts took care of business with a blowout road win against the Panthers, while the Patriots failed to capitalize on a weak Washington Commanders defense following the Chase Young and Montez Sweat trades.

This has the look of a low-scoring game in Germany, just like we saw last week with the Chiefs and Dolphins.

Look for promising first-year coach Shane Steichen to devise the right offensive game plan en route to a win over the lowly Patriots.

Houston Texans @ Cincinnati Bengals

Nov. 12, 1 p.m. ET

  • Texans +7 (-110) @ Bengals -7 (-110)

Former Ohio State star quarterback C.J. Stroud returns to the Buckeye State to go toe-to-toe with Joe Burrow in Cincinnati.

Stroud was phenomenal in Houston’s comeback win over the Tampa Bay Buccaneers, but Burrow is completely locked in following two wins over the 49ers and Bills.

Look for the Bengals to get it done at home in our NFL bet of the day.

Tennessee Titans @ Tampa Bay Buccaneers

Nov. 12, 1 p.m. ET

  • Titans +1 (-110) @ Buccaneers -1 (-110)

Rookie quarterback Will Levis has at least made the Titans’ offense more exciting in his two starts so far.

But this has the look of an ugly, low-scoring game against the Bucs.

Look for Baker Mayfield to take advantage of a vulnerable Titans secondary in this spot.

Cleveland Browns @ Baltimore Ravens

Nov. 12, 1 p.m. ET

  • Browns +6 (-110) @ Ravens -6 (-110)

This is a clash between two AFC North contenders, so we can expect it to come down to the wire.

The Ravens have blown out playoff teams like the Seattle Seahawks and Detroit Lions at home, but this is a different story against the division-rival Browns.

Expect Cleveland to keep it close in a low-scoring game that could be decided by a late field goal.

San Francisco 49ers @ Jacksonville Jaguars

Nov. 12, 1 p.m. ET

  • 49ers -3 (-110) @ Jaguars +3 (-110)

The 49ers look to snap their three-game losing streak as they come out of their bye rejuvenated following the Chase Young trade.

San Francisco now has a scary duo of pass rushers with Young and Nick Bosa.

While the Jaguars have been stout on defense in their own right, this looks like a 49ers bounce-back win.

New Orleans Saints @ Minnesota Vikings

Nov. 12, 1 p.m. ET

  • Saints -2.5 (-110) @ Vikings -2.5 (-110)

The Saints escaped with a home win over the Bears, while the Vikings had a dramatic come-from-behind win with new quarterback Joshua Dobbs.

From what we’ve seen from New Orleans this year, I don’t think we can trust them on the road.

Take the points with the Vikings behind another solid performance from Dobbs.

Green Bay Packers @ Pittsburgh Steelers

Nov. 12, 1 p.m. ET

  • Packers +3.5 (-110) @ Steelers -3.5 (-110)

The Steelers continue to win ugly, narrowly defeating the Titans despite being out-gained in yardage, while the Packers took advantage of facing Brett Rypien instead of Matthew Stafford in Week 9.

I don’t think we can trust the Steelers laying 3.5 points with how Kenny Pickett has played so far.

For that reason, take the Packers +3.5 in what should be a low-scoring matchup.

Atlanta Falcons @ Arizona Cardinals

Nov. 12, 4:05 p.m. ET

  • Falcons -2 (-110) @ Cardinals +2 (-110)

Falcons’ head coach Arthur Smith continues to demonstrate his failure in putting his best players in a position to succeed, limiting stud running back Bijan Robinson‘s touches again in Week 9.

We could see Kyler Murray back for this game, which would give the Cardinals the edge in this spot.

Roll with the Cardinals +2 against the Falcons.

Detroit Lions @ Los Angeles Chargers

Nov. 12, 4:05 p.m. ET

  • Lions -1.5 (-110) @ Chargers +1.5 (-110)

You could argue that this is the most exciting matchup on the slate in what should be a high-scoring affair.

The Lions are coming off their bye, while the Chargers return home after taking on the Jets.

We all know that the Chargers don’t have much home-field advantage, so it’s no surprise to see the Lions as road favorites. Look for Detroit to get it done with a win off their bye.

New York Giants @ Dallas Cowboys

Nov. 12, 4:25 p.m. ET

  • Giants +16 (-110) @ Cowboys -16 (-110)

The Cowboys are massive favorites in this spot because of the Giants’ issues at quarterback, with Daniel Jones and Tyrod Taylor both out.

We could see New York forced to start Tommy DeVito, who has struggled in limited action. There’s also a reasonable chance they’ll bring in a quarterback, perhaps like Carson Wentz.

It’s hard to see New York keeping it close against the Cowboys here, so let’s roll with Dallas.

Washington Commanders @ Seattle Seahawks

Nov. 12, 4:25 p.m. ET

  • Commanders +6.5 (-110) @ Seahawks -6.5 (-110)

The Commanders were able to come through with a road win behind another strong game from Sam Howell in Week 9, while the Seahawks got blown out by the Ravens.

Look for Seattle to bounce back in a big way against one of the worst defenses in the NFL, which got even weaker following the Chase Young and Montez Sweat trades.

Take the Seahawks to get it done in this spot.

New York Jets @ Las Vegas Raiders

Nov. 12, 8:20 p.m. ET (SNF)

  • Jets -2.5 (-110) @ Raiders +2.5 (-110)

The Jets head to Vegas to take on a Raiders team that looks rejuvenated following the firing of Josh McDaniels.

The Raiders blew out the Giants and should be able to keep it close against the Jets.

Take Vegas plus the points against the Jets here.

Denver Broncos @ Buffalo Bills

Nov. 13, 8:20 p.m. ET (MNF)

  • Broncos +7.5 (-110) @ Bills -7.5 (-110)

This looks like a get-right spot for the Bills at home against the Broncos.

Denver is coming off the bye, but they don’t have enough firepower on offense to keep up with Josh Allen, Stefon Diggs, and emerging rookie Dalton Kincaid.

We could see a blowout from Buffalo here.


Frank Ammirante

Frank Ammirante is a Senior Sports Writer at The Game Day. Previously, he wrote for 4for4 Football and RotoBaller. Frank is a member of the Fantasy Sports Writer's Association while maintaining an active presence within the community. He has competed in industry contests like the Scott Fish Bowl, The Great Fantasy Baseball Invitational, and more. Frank will be making his debut in Tout Wars this year. He's got a diverse sporting background, but specializes in football and baseball.

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