AFC South Odds 2026

The AFC South provided one of the NFL’s most competitive divisional races last season, with the Jacksonville Jaguars winning their final nine games to outlast the Houston Texans.

That result was quite unexpected at the campaign’s midpoint, as the Indianapolis Colts posted a 7-1 record across their first eight games before collapsing down the stretch.

Heading into 2026, there are plenty of intriguing storylines in this division, which always seems difficult to predict accurately.

Below, I’ll examine the latest AFC South winner odds and make my division champion prediction for the upcoming season.

AFC South Winner Odds 2026

These AFC South betting odds are current as of Thursday, July 30, and courtesy of DraftKings Sportsbook. Be careful, as many NFL odds may shift as we get closer to the 2026 NFL season.

• Houston Texans (+110)
• Jacksonville Jaguars (+245)
• Indianapolis Colts (+380)
• Tennessee Titans (+800)

Keep track of pro football futures this offseason with our NFL futures odds comparison tool:

AFC South Standings 2025

Before we dig into my AFC South predictions, here’s how the division played out last season:

1. Jacksonville Jaguars 13-4
2. Houston Texans 12-5
3. Indianapolis Colts 8-9
4. Tennessee Titans 3-14

AFC South Winner Best Bet

Houston Texans (+110)

I was thoroughly impressed with the job that Liam Coen did in his first season as Jacksonville’s head coach, but I’m a bit concerned that the Jaguars didn’t do enough to replace outgoing free agents Travis Etienne Jr. (New Orleans) and Devin Lloyd (Carolina).

On the other hand, Houston was proactive in its attempts to shore up its offensive line and rushing attack this offseason, bringing in left guard Wyatt Teller, right tackle Braden Smith, and trading for running back David Montgomery.

Those additions should help quarterback C.J. Stroud, who was dismal in a season-ending Divisional Round defeat to the Patriots in January, but also didn’t have a lot of help. Star wideout Nico Collins missed that game with a concussion, and the Texans played all of last season without promising young receiver Tank Dell, who is expected to return from a devastating leg injury this fall.

Any improvement on offense will go a long way in supporting one of the NFL’s most dominant defenses, which ranked first in yards allowed (277.2 per game) and second in points allowed (17.4).

DeMeco Ryans’ squad has won the division twice and reached the playoffs in all three of his seasons in charge, so I’m backing the Texans to win the AFC South at +110 odds as my NFL pick of the day.

AFC South Winner Sleeper Pick

Tennessee Titans (+800)

The Titans have finished last in the AFC South each of the past three seasons, but it’s not uncommon to see teams go from worst to first in this division. The Jaguars and Texans have both accomplished that feat this decade, with new coaching hires triggering impressive turnarounds.

Well, Tennessee has a new head coach in Robert Saleh, and perhaps more importantly, an experienced quarterback guru in offensive coordinator Brian Daboll, who will try to get the best out of second-year signal-caller Cam Ward. Last year’s No. 1 overall pick has new weapons to work with in former Ohio State wide receiver Carnell Tate and free-agent addition Wan’Dale Robinson, who played under Daboll with the New York Giants.

Saleh has historically been a strong defensive play-caller, and he’s reuniting with several of his former players, including John Franklin-Myers and Jermaine Johnson II, who have had success in his system before. The Titans also have an elite game-wrecker in Jeffery Simmons, who had more than twice as many sacks (11) as his next closest teammate.

While there are a lot of moving parts in Tennessee, it wouldn’t shock me if the Titans surprised some folks this season, especially if Ward can make significant strides under Daboll’s tutelage.

AFC South Winner By Year