Jaguars vs Colts Predictions | Best Bets & Odds

Last Updated: Oct 11, 2022

Ever since the Colts were shut out in Jacksonville in Week 2, these teams have gone in opposite directions. Jacksonville has lost two of its last three, while Indianapolis has earned two impressive wins over the Chiefs and Broncos.

The Jags haven’t won in Indy since Oct. 2017. Will they be able to pull off the upset this time around?

Continue reading our Jacksonville vs Indianapolis betting odds and predictions for more.

Jaguars vs Colts Odds

As of Monday, the Colts are listed as slight 1.5-point favorites. This is also expected to be a low-scoring game, with the total set at 42 points.

Take a look at the best Jaguars odds and Colts odds for the 2022 NFL season.

Jaguars vs Colts Implied Totals

Colts 21.75, Jaguars 20.25

Oddsmakers have the Colts winning by roughly a point in a low-scoring affair with only a handful of touchdowns.

Jaguars vs Colts Pick of the Day

Read more on this Jaguars vs Colts bet below.

Jaguars vs Colts Prediction

Jaguars 23, Colts 17

The wins have been unbearably ugly, but the Colts are at least beginning to resemble the team we thought they could be at the beginning of the year. The defense has been most responsible for those victories, as Indianapolis allowed a combined 26 points in their wins over the Chiefs and Broncos.

Matt Ryan‘s struggles have been part of the problem for this offense. The veteran quarterback has thrown seven interceptions to five touchdowns, and his 79.8 quarterback rating is the lowest mark he’s posted in his NFL career. He won’t be catching any breaks against this Jaguars’ defense, either.

Unfortunately for Colts fans, this one may come down to Ryan’s arm. Jonathan Taylor and Nyheim Hines aren’t guaranteed to be ready to go against the Jags, which could give Jacksonville a significant upper hand. Trevor Lawrence‘s squad is also coming off of an embarrassing loss in Houston.

In the end, I’m expecting a bounce-back performance from the Jaguars. Indianapolis will keep things close, but Jacksonville’s offense will produce just enough points to give them the victory on the road.

Jaguars vs Colts Bet Tips

Here are some Jaguars vs Colts betting trends to consider before placing your bets:

  • The Jaguars won their Week 2 meeting with the Colts, 24-0.
  • Both the Colts and Jaguars are 2-3 against the spread.
  • The Jaguars are 7-4 against the Colts dating back to Oct. 2017.

Jaguars vs Colts Best Bets

Jaguars Moneyline (+112) at BetRivers Sportsbook

I like the value available here on the Jags to win outright. They’ve already dominated this Colts team once this season, and after a disappointing performance in Houston this past week, they’ll feel comfortable taking on Indianapolis.

Before placing this bet, get the best Jaguars promo codes.

UNDER 42 Points (-113) at BetRivers

Both of these teams have above-average defenses and streaky offenses. I only see the Over hitting in this game if both offenses are at their best, and that seems relatively unlikely. It’ll be a sweat, but I like the Under.

Before placing this bet, get the best Colts promo codes.


Garrett Chorpenning

Garrett Chorpenning is the Lead NBA Editor for The Game Day. His previous work includes covering the LA Clippers for Sports Illustrated and FanSided. He graduated from Ball State University in 2021.

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