The Jaguars are back on home soil after spending the last two weeks going 2-0 in London. They are back above .500 and face AFC South foe Indianapolis with first place in the division on the line.
Unfortunately for the Colts, they will be without star rookie QB Anthony Richardson, who landed on the IR with a shoulder injury.
Let’s dive into the odds and best bets for this divisional showdown.
Colts vs Jaguars Odds
NFL odds used for this Indianapolis vs Jacksonville preview were found at Caesars Sportsbook and are current as of October 11th at 2 p.m. ET.
- Moneyline: Jaguars (-210) • Colts (+175)
- Spread: Jaguars -4 (-110) • Colts +4 (-110)
- Total Points: Over 45.5 (-110) • Under 45.5 (-110)
- Implied Score: Jaguars 24.75, Colts 20.75
Colts vs Jaguars Predictions
Score Pick: Jaguars 31, Colts 17
The last time the Colts won in Jacksonville was in 2014, when Andrew Luck was under center in Indianapolis. The Jaguars won the first meeting between the two sides 31-21 in Week 1 on the road, and they should roll again in this matchup.
Gardner Minshew is slated to start for the Colts, and although he’s not the worst backup QB in the league, he doesn’t have the firepower that Richardson brings to the Colts offense. Minshew threw for 227 in their Week 3 win against the Ravens, but the Colts relied on their run game to win that contest.
The Jaguars passing game is on the rise and will go up against a poor secondary in the Colts.
Colts vs Jaguars Best Bets & Props
Jaguars -4 (-110)
Caesars Sportsbook • WAGER: 1 Unit
Trevor Lawrence is coming off a 315-yard passing game against the Bills and had 241 yards in their first meeting against the Colts. The Colts’ secondary has allowed a 100-yard receiver in four of their five games this season, including 101 yards to Calvin Ridley in Week 1.
The Colts do have Jonathan Taylor back in this contest, and their only way of staying in this game will be by running the ball and keeping the ball out of Lawrence’s hand. The Jaguars have too much offensive firepower in their passing game for the Colts defense to contain.
The Jaguars will convincingly win this matchup at home, and this is my NFL bet of the week.
Over 45.5 (-110)
Caesars Sportsbook • WAGER: 1 Unit
This game has the potential to be high-scoring, with two of the worst passing defenses in the league. The Colts have given up the third-most yards to QBs on the season, with the Jaguars giving up the fourth most.
The Jaguars also only have nine sacks on the season, so Minshew will have time to keep up with the Jaguars scoring.
Jaguars Over 25.5 (-110)
Caesars Sportsbook • WAGER: 1 Unit
The Jaguars scored 31 on the road against this Colts team in Week 1 and should have a better day at home in this contest. Jacksonville has also hit this number in three of their last four games against the Colts.
Colts vs Jaguars Same Game Parlay
Colts vs Jaguars SGP (+198)
DraftKings Sportsbook • WAGER: 0.5 Units
- Jaguars (-198)
- Jaguars Over 24.5 (-108)
- Both Teams Score 15+ (-205)
As I mentioned, the Jaguars have not lost to the Colts at home since 2014, so adding Jaguars moneyline to the parlay is the safe leg. I expect the Jaguars passing offense to have a field day on Sunday and score at least 25 points.
Gardner Minshew is a serviceable backup QB, and the game script will force him to throw the ball. The Jaguars have conceded at least 15 points in four of their five games this year, so I like both teams to score at least 15 points in this contest.
