Eagles vs Colts Predictions & Odds

Last Updated: Nov 17, 2022

The Indianapolis Colts earned a surprising victory this past week, defeating the Las Vegas Raiders in their first game under Jeff Saturday.

However, it may be time for Colts fans to turn down the optimism a bit, as Indianapolis will take on the Philadelphia Eagles in Week 11, who will be out to make up for their surprising loss to the Washington Commanders this past week.

See how I expect this matchup to go with my Philadelphia vs Indianapolis best bets and predictions for Week 11.

Eagles vs Colts Odds

As of Tuesday, Nov. 15 at Caesars Sportsbook, the Colts are listed as 7.5-point home underdogs, with the total set at 44.5 points. Despite the fact that Philly will be coming into this one on short rest, oddsmakers aren’t giving Indianapolis much of a chance.

Take a look at the best Eagles odds and Colts odds for the 2022 NFL season.

Eagles vs Colts Implied Totals

Eagles 26, Colts 18.5

The oddsmakers have the Eagles winning an average-scoring game by a bit more than a touchdown. Surprisingly, the Colts are expected to score 18.5 points, despite the fact that they rank 30th in points per game.

Eagles vs Colts Pick of the Day

Read more on this Eagles vs Colts bet below.

Eagles vs Colts Prediction

Eagles 27, Colts 17

There really isn’t much that needs to be said about this one. The Eagles, even on short rest, are far superior to the Colts in terms of overall talent and coaching.

Indianapolis will have a difficult time scoring against an Eagles defense that ranks seventh in points allowed per game, and we could see Philadelphia go even more run-heavy than we’re used to in an attempt to preserve energy and play conservatively.

Even still, I could see the Colts giving up a handful of scores. This defense is nothing to write home about, and the Eagles have the most potent offense the Colts have seen since Week 3.

Eagles vs Colts Bet Tips

Here are a few Eagles vs Colts betting trends to consider before making your bets:

  • The Eagles are 5-4 against the spread; the Colts are 4-6.
  • Philadelphia is 1-0 ATS with a rest disadvantage.
  • Overs are a combined 8-11 for the Colts and Eagles this season.

Eagles vs Colts Best Bets

Eagles -7.5 (-110) at Caesars Sportsbook

WAGER: 1 Unit

I think this one could be close — and by close, I mean within 10 points — but I still expect the Eagles to cover. While the Colts’ win over the Raiders was unexpected, it still wasn’t particularly impressive, and Philadelphia remains a fantastic team on both sides of the ball.

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Under 44.5 Points (-110) at Caesars

WAGER: 1 Unit

The Colts are very much an Under football team. So far, eight of their 1o games have failed to reach the Over. And seeing as how the Eagles are dominant on defense, I don’t really foresee Indianapolis providing much in terms of scoring here.

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Eagles vs Colts Props

Check out the best Eagles vs Colts player prop bets this week with our props comparison tool. Click on “Show More Games" below to find the Philadelphia vs Indianapolis game and see all of its prop bets.


Garrett Chorpenning

Garrett Chorpenning is the Lead NBA Editor for The Game Day. His previous work includes covering the LA Clippers for Sports Illustrated and FanSided. He graduated from Ball State University in 2021.

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