Cardinals vs Seahawks Week 11 Prop Bets | Props for Alternate Spread, Winning Margin, & More

Frank AmmiranteSenior Sports Writer
Last Updated: Nov 19, 2021

The Arizona Cardinals (8-2) take on the Seattle Seahawks (3-6) in an NFC West divisional matchup in Week 11.

The Cardinals are coming off a blowout home loss against the Carolina Panthers. However, it looks like quarterback Kyler Murray is trending towards playing on Sunday, although star wideout DeAndre Hopkins will remain out for another week.

The Seahawks are in a desperate situation right now. At 3-6, they need a win to keep their fading wild card hopes alive. The offense looked out of sync against the Green Bay Packers last week, but we can project a better performance since their stars are now fully healthy, namely quarterback Russell Wilson.

Let’s dive in to find the best Cardinals vs Seahawks prop bets.

Please note that all NFL gameday odds are current as of 4:00 p.m. ET on Thursday, November 18.

Cardinals vs Seahawks Prop Bets: NFL Week 11 Prop Betting Picks

Alternate Spread: Seahawks +3.5 (-160) at Caesars

I don’t mind laying the juice and buying a full point on this game. Getting past that key number of three points is huge, especially for a game that I project to be close.

Russell Wilson looked rusty in his return last week, but this is a quarterback who had averaged at least nine yards per attempt in four of five starts prior to this game. He’s as efficient as ever and we should see a bounce-back this week.

Speaking of rust, that’s exactly what we could see from Kyler Murray if he’s able to return this week. Even if Arizona wins this game, I don’t expect it to be by more than a field goal.

I like the Seahawks to win outright, so getting 3.5 points is huge.

Cardinals vs Seahawks Player Prop Bets to Make This Week

Check out the best NFL player prop bets this week with our props comparison tool, including projections to help you make the best decisions.

Click “Place Bet" to unlock the associated sportsbook’s welcome offer and place your bet. Select the game you want to highlight, including Cardinals vs Seahawks.

Learn more about NFL prop bets and the best sportsbooks for prop betting.

Winning Margin: Seahawks by 7-12 Points (+575) at Caesars

Since I’m predicting the Seahawks to win this game, why not sprinkle a small wager on the winning margin?

When betting on the winning margin, it’s better to target the best value because it’s obviously harder to predict. While the Seahawks by 1-6 points (+310) seems more likely, I like the value on 7-12 points (+575).

The Seahawks are the desperate team here. We saw what happened in the last division game in the NFC West. The Rams visited a 49ers team that badly needed a win and San Francisco proceeded to dominate all three phases, winning the game 31-10.

Give me the home underdog in a tough divisional game. Seattle should get it done this week, making this our NFL pick of the day.

Team Total: Seahawks Over 23.5 Points (-115) at Caesars

The Seahawks have averaged 25.75 points per game in Russell Wilson’s full games this season. While Arizona has a good defense, the Cardinals have allowed 24 or more points in two of their last three games.

I really think that this is a get-right spot for Wilson and the Seahawks’ passing game. Look for DK Metcalf and Tyler Lockett to have a better showing than last week, where they combined for five receptions and 89 receiving yards.

Roll with the over on the Seahawks’ team total here.

Thanks for reading our NFL Week 11 Cardinals vs Seahawks Prop Bets! For more NFL Week 11 betting tips and tipster picks, check out our NFL Week 11 Best Bets and NFL Week 11 Props.


Frank Ammirante

Frank Ammirante is a Senior Sports Writer at The Game Day. Previously, he wrote for 4for4 Football and RotoBaller. Frank is a member of the Fantasy Sports Writer's Association while maintaining an active presence within the community. He has competed in industry contests like the Scott Fish Bowl, The Great Fantasy Baseball Invitational, and more. Frank will be making his debut in Tout Wars this year. He's got a diverse sporting background, but specializes in football and baseball.

Related articles


Get $1,500 in Bonus Bets

5 stars

Bet $5, Get $150 in Bonus Bets or First Bet Safety Net

5 stars

Get A $1,500 No Sweat Bet + NBA SGP Token

5 stars

Get A Bonus Bet Up to $1,000

5 stars

Bet $5, Get $150 in Bonus Bets

5 stars

Get Up To $250 Second Chance Bonus Bet

5 stars

If you or someone you know has a gambling problem and wants help, please call 1-800-GAMBLER.

21+ and present in OH. Gambling Problem? Call or text 1-800-GAMBLER (CO, DC, IL, IN, LA, MD, MS, NJ, OH, PA, TN, VA, WV, WY).

Call 877-8-HOPENY or text HOPENY (467369) (NY).

Please Gamble Responsibly. Call 1-800-NEXT-STEP (AZ), 1-800-522-4700 (KS, NV), 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-270-7117 for confidential help (MI).

All betting content on is exclusively intended for audience members 21 years and older who are permitted to gamble in legal states. The Game Day may earn revenue from site visitor referrals to betting services.

Responsible Gaming: Many sportsbooks offer ways to encourage responsible gaming, including the establishment of limits to deposits, spending, and time dedicated to betting.

The Game Day is a TGD Marketing Ltd. endeavor.