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NFL Week 7 Predictions & Best Bets

Last Updated: Oct 17, 2025

NFL Week 7 has arrived.

We have a 15-game slate to work with this week, as just the Buffalo Bills and Baltimore Ravens are on a bye.

Without any further ado, let’s dive into my NFL Week 7 best bets.

NFL odds used for these Week 7 picks are current as of Friday, Oct. 17, and courtesy of DraftKings Sportsbook.

NFL Week 7 Best Bet

Jaguars +3 (-105) vs Rams

DraftKings Sportsbook • WAGER: 1 Unit

The Jaguars have plenty of experience playing in London, and they’ve enjoyed substantial success across the pond in recent seasons, winning three of their last four trips abroad.

Liam Coen’s squad will be eager to bounce back from Sunday’s 20-12 setback against the Seattle Seahawks, which halted a three-game winning streak.

Jacksonville has spent the week in London, which I think will give them a time-clock advantage over the Rams, who stayed on the east coast following Sunday’s 17-3 win in Baltimore and flew over on Friday.

The Jags should at least be able to stay within the number against a Los Angeles side that will be without star wide receiver Puka Nacua in this matchup. Back Trevor Lawrence and Co. with your NFL bet of the day.


Sportsbook Play of the Day


NFL Week 7 ATS Pick

Browns -2.5 (-115) vs Dolphins

DraftKings Sportsbook • WAGER: 1 Unit

This game isn’t the most appetizing one on the Week 7 slate, but I like the Browns to beat the Dolphins by at least a field goal at home.

Cleveland boasts one of the league’s best defenses, while Miami’s unit struggles in almost every major category.

While the Dolphins have the better quarterback in this matchup of southpaws, the passing attack shouldn’t be a major part of the plan for either offense in wet and windy weather conditions.

Look for the Browns to ride rookie running back Quinshon Judkins against a Miami defense that allows the most rushing yards in the NFL (168.5 per game) and for Cleveland to cover this small spread.

NFL Week 7 Over/Under Pick

Panthers vs Jets: Under 42.5 Points (-115)

DraftKings Sportsbook • WAGER: 1 Unit

The Jets defense finally showed up last week in London, holding the Broncos to 13 points with an effort that should’ve been good enough to win any game.

However, New York’s offense managed just 11 points and somehow netted -10 passing yards, as quarterback Justin Fields took nine sacks and couldn’t move the ball through the air whatsoever.

I don’t expect Fields and the offense to figure things out this week, especially with top wideout Garrett Wilson doubtful to play with a knee injury.

The Jets will likely try to grind out this game on the ground against a Carolina rush defense that has been decent this season, ranking ninth in rushing yards per game allowed (94.5).

The Panthers have also leaned on Rico Dowdle and the rushing attack in recent weeks, so this game clock should be constantly on the move.

Author

John Arlia

Before joining The Game Day, John served as the National Writer for the United Soccer League, where he primarily covered the USL Championship out of the league’s headquarters in Tampa, FL. A devout soccer fan, John attended the men’s World Cups in Brazil and Russia and can’t wait for the 2026 edition to come to North America. Having also written for Sporting News Canada since getting his master’s from the Walter Cronkite School of Journalism at ASU, John has acquired a diverse sporting background, but considers football, golf, and soccer his three strong suits.

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