2021 NFL Early Lines Week 2 — Opening Betting Odds & Implied Totals for NFL Games This Week

Checking NFL early lines each week gives prospective football bettors a solid idea of trends that the sportsbooks and the public will enact for that week’s action.

To offer our NFL readers perspective, we’ve gathered some Week 2 NFL Opening Lines and Odds, including moneyline, against the spread, Over/Under and implied total information to start your betting off right.

2021 NFL Early Lines Week 2: Opening Odds & Betting Info for NFL Games This Week

All Week 2 NFL gameday odds and lines are provided courtesy of Caesars Sportsbook, current as of 11:45 p.m. ET on Sunday, September 12.

New York Giants at Washington Football Team (Thursday Night Football, 8:20 p.m. ET)

  • Moneyline: Giants (+190), WFT (-230)
  • Spread: Giants +4 (-110), WFT -4 (-110)
  • Over/Under Points Total: Over 42.5 (-110), Under 42.5 (-110)
  • Implied Score: WFT 23.25, Giants 19.25

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Las Vegas Raiders at Pittsburgh Steelers (1 p.m. ET)

  • Moneyline: Raiders (+220), Steelers (-270)
  • Spread: Raiders +6 (-110), Steelers -6 (-110)
  • Over/Under Points Total: Over 48.5 (-110), Under 48.5 (-110)
  • Implied Score: Steelers 27.25, Raiders 21.25

San Francisco 49ers at Philadelphia Eagles (1 p.m. ET)

  • Moneyline: 49ers (-170), Eagles (+145)
  • Spread: 49ers -3 (-115), Eagles +3 (-105)
  • Over/Under Points Total: Over 48 (-110)/Under 48 (-110)
  • Implied Point Totals: 49ers 25.5,  Eagles 22.5

One of the marquee games is this matchup of 1-0 teams. San Francisco held on after blowing a huge lead against Detroit, but Jalen Hurts‘ Eagles commanded a road win over the Falcons.

Will San Francisco turn to Trey Lance under center yet and create a matchup of the two most mobile quarterbacks in the game? Probably not, since Jimmy Garoppolo was efficient in Sunday’s victory.

Still, the Over looks to be in play, given that the Niners just let Jared Goff’s Lions put up 33 points.

over-under

-110

49ers @ Eagles: Over 48 Total Points (NFL Week 1)

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Houston Texans at Cleveland Browns (1 p.m. ET)

  • Moneyline: Texans (+425), Browns -600
  • Spread: Texans +11.5 (-110), Browns -11.5 (-110)
  • Over/Under Points Total: Over 48 (-110), Under 48 (-110)
  • Implied Point Totals: Browns 29.75, Texans 18.25

Denver Broncos at Jacksonville Jaguars (1 p.m. ET)

  • Moneyline: Broncos (-280), Jaguars (+230)
  • Spread: Broncos -6 (-110), Jaguars +6 (-110)
  • Over/Under Points Total: Over 44 (-110), Under 44 (-110)
  • Implied Point Totals: Broncos 25, Jaguars 19

New Orleans Saints at Carolina Panthers (1 p.m. ET)

  • Moneyline: Saints (-170), Panthers (+145)
  • Spread: Saints -3 (-110), Panthers +3 (-110)
  • Over/Under Points Total: Over 46 (-110), Under 46 (-110)
  • Implied Point Totals: Saints 24.5, Panthers 21.5

Los Angeles Rams at Indianapolis Colts (1 p.m. ET)

  • Moneyline: Rams (-110), Colts (-110)
  • Spread: Rams -3.5 (-115), Colts +3.5 (-104)
  • Over/Under Points Total: Over 47.5 (-110), Under 47.5 (-110)
  • Implied Point Totals: Rams 25.5, Colts 22

Buffalo Bills at Miami Dolphins (1 p.m. ET)

  • Moneyline: Bills (-180), Dolphins (+155)
  • Spread: Bills -3.5 (-110), Dolphins +3.5 (-110)
  • Over/Under Points Total: Over 47.5 (-110), Under 47.5 (-110)
  • Implied Point Totals: Bills 25.5, Dolphins 22

New England Patriots at New York Jets (1 p.m. ET)

  • Moneyline: Patriots (-220), Jets (+170)
  • Spread: Patriots -3.5 (-120), Jets +3.5 (+100)
  • Over/Under Points Total: Over 43 (-110), Under 43 (-110)
  • Implied Point Totals: Patriots 23.25, Jets 19.75

Cincinnati Bengals at Chicago Bears (1 p.m. ET)

  • Moneyline: Bengals (-115), Bears (-104)
  • Spread: Bengals +3.5 (-115), Bears -3.5 (-104)
  • Over/Under Points Total: Over 45.5 (-110), Under 45.5 (-110)
  • Implied Point Totals: Bears 24.5, Bengals 21

Joe Burrow‘s Bengals outlasted the Vikings in overtime to win their season opener but travel to face a tough Bears defense at home. Don’t let the Rams’ rout of Chicago on Sunday night take anything away from a Khalil Mack matchup with a questionable Bengals offensive line.

Atlanta Falcons at Tampa Bay Buccaneers (4:05 p.m. ET)

  • Moneyline: Falcons (+550), Buccaneers (-800)
  • Spread: Falcons +12.5 (-110), Buccaneers -12.5 (-110)
  • Over/Under Points Total: Over 52.5 (-110), Under 52.5 (-110)
  • Implied Point Totals: Buccaneers 32.5, Falcons 20

Minnesota Vikings at Arizona Cardinals (4:05 p.m. ET)

  • Moneyline: Vikings (+180), Cardinals (-220)
  • Spread: Vikings +4.5 (-115), Cardinals -4.5 (-105)
  • Over/Under Points Total: Over 51 (-110), Under 51 (-110)
  • Implied Point Totals: Cardinals 27.75, Vikings 23.25

Tennessee Titans at Seattle Seahawks (4:25 p.m. ET)

  • Moneyline: Titans (+205), Seahawks (-250)
  • Spread: Titans +6 (-115), Seahawks -6 (-105)
  • Over/Under Points Total: Over 52.5 (-110), Under 52.5 (-110)
  • Implied Point Totals: Seahawks 29.25, Titans 23.25

Dallas Cowboys at Los Angeles Chargers (4:25 p.m. ET)

  • Moneyline: Cowboys (+125), Chargers (-145)
  • Spread: Cowboys +3 (-120), Chargers -3 (+100)
  • Over/Under Points Total: Over 52.5 (-110), Under 52.5 (-110)
  • Implied Point Totals: Chargers 27.75, Cowboys 24.75

Kansas City Chiefs at Baltimore Ravens (Sunday Night Football, 8:20 p.m. ET)

  • Moneyline: Chiefs (-140), Ravens (+120)
  • Spread: Chiefs -2.5 (-110), Ravens +2.5 (-110)
  • Over/Under Points Total: Over 55.5 (-110), Under 55.5 (-110)
  • Implied Point Totals: Chiefs 29, Ravens 26.5

Detroit Lions at Green Bay Packers (Monday Night Football, 8:15 p.m. ET)

  • Moneyline: TBA
  • Spread: TBA
  • Over/Under Points Total: TBA
  • Implied Point Totals: TBA

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